drugset / Trial / NCT02473354

Predictors of Opioid-Induced Respiratory Depression (OIRD)

NCT02473354

Phase 1 Completed 30 enrolled Duke University
NaSingle-groupOpen-labelHealth-services research

Summary

Purpose of the Study: (1) To classify an individual subject's ventilatory response in terms of respiratory depression to a bolus of remifentanil under normoxic and hyperoxic conditions. (2) Measurement of specific respiratory parameters to predict the opioid-induced respiratory depression (OIRD) response.

Timeline

Start
2015-04
Primary completion
2018-04-29
Completion
2018-04-29

Drugs

EvaluationDrugModalityDoseRoute
Subject Remifentanil Small molecule
Background Oxygen Other / unclassified Inhaled