drugset / Trial / NCT04435834

Individual Cerebral Hemodynamic Oxygenation Relationships

NCT04435834

Phase 4 Recruiting 30 enrolled Matthew Borzage
RandomizedParallel-groupDouble-blindBasic science

Summary

This is a randomized controlled trial in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by two types of anesthesia: propofol or sevoflurane. Subjects who require clinical anesthesia for a clinical MRI and for whom the use of propofol and sevoflurane are in clinical equipoise will be offered to have the anesthesia they will receive during their MRI randomized. All eligible subjects will be asked to provide informed consent before participating in the study.

Timeline

Start
2020-06-09
Primary completion
2026-09-10
Completion
2026-09-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Propofol Small molecule 100 ug/kg
Subject Propofol Small molecule 300 ug/kg
Subject Sevoflurane Other / unclassified 2.8 % Inhaled
Subject Sevoflurane Other / unclassified 3 % Inhaled
Subject Sevoflurane Other / unclassified 3.3 % Inhaled

Indications

No indication recorded.