drugset / Trial / NCT00541918
COGNITIVE - Cognitive Function After Sevoflurane or Propofol Anesthesia for Open-heart Operations
RandomizedCrossoverDouble-blindPrevention
Summary
The aim of the study is to prove whether general anesthesia with inhaled sevoflurane reduces the frequency of neurological and cognitive impairment after open-heart operations with use of cardiopulmonary by-pass (CPB) in comparison with intravenous anesthesia with propofol.
Timeline
- Start
- 2007-06
- Primary completion
- 2015-04
- Completion
- 2015-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | — | Intravenous |
| Subject | Sevoflurane | Other / unclassified | — | Inhaled |