drugset / Trial / NCT05663242
The Effects of Using Different Anesthetics on the Prognosis of Primary Lung Tumors and Its Mechanism of Action
RandomizedParallel-groupDouble-blindTreatment
Summary
This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary early lung cancer. The study will enroll approximately 300 volunteers to compare the progression-free or overall survival in patients undergoing video-assisted thoracoscopic surgery (VATS) for primary lung tumors between propofol and sevoflurane for the maintenance of anesthesia.
Timeline
- Start
- 2022-12-27
- Primary completion
- 2026-11-30
- Completion
- 2026-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Propofol | Small molecule | 2 ug/ml | Intravenous |
| Subject | Propofol | Small molecule | 4 ug/ml | Intravenous |
| Subject | Sevoflurane | Other / unclassified | 1 % | Inhaled |
| Subject | Sevoflurane | Other / unclassified | 3 % | Inhaled |