drugset / Trial / NCT01972230
Sevoflurane Protective Effect on Ischemia Reperfusion Injury in Microvascular Surgery
RandomizedParallel-groupOpen-labelTreatment
Summary
This study aimed to evaluate the possible protective effect of anesthetic technique balanced (BAL) compared to total intravenous anesthetic technique (TIVA-TCI) in ischemia reperfusion injury in microvascular flap in plastic surgery. The investigators will evaluate the viability of the flap using tissue oximetry monitoring and the level of biochemical markers in a circle at the end of the intervention.
Timeline
- Start
- 2013-01
- Primary completion
- 2015-04
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | 3 mg/ml | — |
| Comparator | Propofol | Small molecule | 4 mg/ml | — |
| Subject | Sevoflurane | Other / unclassified | — | — |
| Comparator | Remifentanil | Small molecule | 1 ng/ml | — |
| Comparator | Remifentanil | Small molecule | 3 ng/ml | — |
Indications
No indication recorded.