drugset / Trial / NCT07601256

Inhalational Versus Intravenous Anesthesia on Postoperative Lung Injury in Septic Patients Undergoing Surgery

NCT07601256

Not yet recruiting 480 enrolled Sixth Affiliated Hospital, Sun Yat-sen University
RandomizedParallel-groupQuadruple-blindPrevention

Summary

This randomized controlled trial will compare the effects of intraoperative inhalational anesthesia versus intravenous anesthesia on postoperative lung injury in septic patients undergoing surgery. The primary goal is to determine if the choice of anesthetic technique influences the incidence or severity of this complication. Participants will be randomly assigned to one of the two anesthetic regimens during surgery. They will receive daily in-hospital assessments for lung injury and other outcomes and will be followed for clinical outcomes until 90 days after the procedure.

Timeline

Start
2026-08-15
Primary completion
2030-12-30
Completion
2030-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Cipepofol Small molecule Intravenous
Subject Sevoflurane Other / unclassified Inhaled
Background Remifentanil Small molecule Intravenous