Effect of Anesthetics on Microcirculation in Patients Undergoing Off-pump Coronary Artery Bypass Surgery

NCT03209193 ↗

Phase 4 Completed 72 enrolled Seoul National University Hospital

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Volatile anesthetics, such as sevoflurane and desflurane, are commonly used in patients undergoing cardiac surgeries including off-pump coronary artery bypass. However, the effect of volatile anesthetics on microcirculation in patients undergoing off-pump coronary artery bypass has not been well conducted.

Timeline

Start: 2017-07-04
Primary completion: 2019-11-07
Completion: 2019-11-07

Publications

Cho YJ, Yoo SJ, Nam K, Bae JY, Lee SH, Jeon Y. Effects of anesthetics on microvascular reactivity measured by vascular occlusion tests during off-pump coronary artery bypass surgery: a randomized controlled trial. J Clin Monit Comput. 2021 Oct;35(5):1219-1228. doi: 10.1007/s10877-020-00587-8. Epub 2020 Sep 11.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Desflurane	Other / unclassified	6 %	—
Subject	Sevoflurane	Other / unclassified	2 %	—

Indications

No indication recorded.