Influence of Anesthetics on Clinical Outcome During Cardiac Surgery in Adults
Summary
Abstract Cardiac surgery in adults is associated with the occurrence of post-operative complications. Even minor complications can increase the cost of their treatment. Given the potentially preventable nature of a number of these postoperative complications, preventive methods should be used to improve outcomes after cardiac surgery. One of them, is the choice of anaesthetic technique. Objectives: To evaluate the effects of sevoflurane, isoflurane and propofol on blood oxygen transport function and body energy expenditure during cardiac surgery in adults. Materials and methods. A total of 90 patients were included in the study. All patients were divided into 3 groups: 1- (n=30) included patients who were anesthetized with propofol. The second group (n=30) consisted of patients who underwent sevoflurane inhalation anaesthesia. Group 3 (n=30) was treated with isoflurane. All patients underwent coronary artery bypass grafting under cardiopulmonary bypass.
Timeline
- Start
- 2022-01-22
- Primary completion
- 2022-11-19
- Completion
- 2022-11-26
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Isoflurane | Other / unclassified | 1.1 unknown | — |
| Subject | Isoflurane | Other / unclassified | 1.2 unknown | — |
| Subject | Propofol | Small molecule | 5 mg/kg | Intravenous |
| Subject | Propofol | Small molecule | 6 mg/kg | Intravenous |
| Subject | Sevoflurane | Other / unclassified | 1.7 unknown | Inhaled |
| Subject | Sevoflurane | Other / unclassified | 1.9 unknown | Inhaled |