drugset / Trial / NCT07429292

SPARK Study - Sympathetic Periarterial Radial Block in Healthy Volunteers

NCT07429292

Phase 4 Not yet recruiting 20 enrolled Duke University
RandomizedParallel-groupSingle-blindBasic science

Summary

The SPARK Study evaluates changes in peripheral sympathetic vasomotor activity following a targeted, ultrasound-guided periarterial sympathetic block of the distal radial artery in healthy volunteers. Autonomic reactivity will be assessed before and after the block using digit-specific pulse-amplitude index and infrared thermography during standardized cold pressor testing.

Timeline

Start
2026-09
Primary completion
2026-12
Completion
2027-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Lidocaine Other / unclassified 2 % Other
Subject Lidocaine Other / unclassified 5 ml Other

Indications

No indication recorded.