drugset / Trial / NCT07250867
Safety and Efficacy of Lidocaine Versus Ketamine Infusion for Resistant Orofacial Pain
RandomizedParallel-groupQuadruple-blindTreatment
Summary
A prospective, randomized, double-blind clinical trial comparing the safety and efficacy of intravenous lidocaine, ketamine, and their combination as treatment options for patients suffering from treatment-resistant orofacial pain. The study measures pain reduction primarily using the Visual Analog Scale and evaluates safety and tolerability over a follow-up period of 6 months.
Timeline
- Start
- 2026-01
- Primary completion
- 2027-01
- Completion
- 2027-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketamine | Small molecule | 0.15 mg/kg | Intravenous |
| Subject | Ketamine | Small molecule | 0.3 mg/kg | Intravenous |
| Subject | Lidocaine | Other / unclassified | 2.5 mg/kg | Intravenous |
| Subject | Lidocaine | Other / unclassified | 5 mg/kg | Intravenous |
Indications
No indication recorded.