drugset / Trial / NCT01054547
Topical Formulations of Liposomal Local Anesthetics
Phase 1
Completed
80 enrolled
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo · collab
RandomizedCrossoverTriple-blindHealth-services research
Summary
This blinded cross-over study aim to evaluate the efficacy of topical liposome-encapsulated ropivacaine formulations.
Timeline
- Start
- 2006-09
- Primary completion
- 2006-12
- Completion
- 2007-04
Publications
- Franz-Montan M, de Paula E, Groppo FC, Silva AL, Ranali J, Volpato MC. Liposome-encapsulated ropivacaine for intraoral topical anesthesia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Dec;110(6):800-4. doi: 10.1016/j.tripleo.2010.07.005.
- Franz-Montan M, de Paula E, Groppo FC, Silva AL, Ranali J, Volpato MC. Liposomal delivery system for topical anaesthesia of the palatal mucosa. Br J Oral Maxillofac Surg. 2012 Jan;50(1):60-4. doi: 10.1016/j.bjoms.2010.10.018. Epub 2010 Nov 23.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Benzocaine | Small molecule | 100 mg | Topical |
| Subject | Lidocaine | Other / unclassified | 100 mg | Topical |
| Comparator | Ropivacaine | Other / unclassified | 100 mg | Topical |
| Subject | prilocaine | Small molecule | 100 mg | Topical |
Indications
No indication recorded.