drugset / Trial / NCT00540982
Vinorelbine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Treatment and Liver Dysfunction
Phase 1/2
Completed
47 enrolled
City of Hope Medical Center
National Cancer Institute (NCI) · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy, such as vinorelbine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This pilot trial is studying the side effects and best dose of vinorelbine in treating patients with advanced solid tumors that have not responded to treatment and liver dysfunction.
Timeline
- Start
- 1997-02-20
- Primary completion
- 2010-05-20
- Completion
- 2010-05-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Indocyanine Green | Diagnostic / imaging agent | 0.5 mg/kg | Intravenous |
| Subject | Lidocaine | Other / unclassified | 1 mg/kg | Intravenous |
| Subject | Vinorelbine | Small molecule | 7.5 mg/m2 | Intravenous |
| Subject | Vinorelbine | Small molecule | 30 mg/m2 | Intravenous |