Drugs / Indocyanine Green
Indocyanine Green
also known as
ICG · IC-Green · PULSION · ICG Dye · indocyanine green (IC-Green). · Indocyanine green (ICG) · Indocyanine Green Dye · INFRACYANINE · +4 more
Regulatory milestones approvals, filings & regulatory actions · 3 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | IC-GREEN | — | 2024-12-05 | fda.gov ↗ |
| Label expansion | US (FDA) | SPY AGENT GREEN KIT | — | 2023-06-05 | fda.gov ↗ |
| Approved | US (FDA) | IC-GREEN | — | 1959-02-09 | fda.gov ↗ |
Trials 180 · started per year
today
US approved 1959
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 016 trials | ||||||
| Phase 0 | NCT07658768 | Sep 2026 → May 2027 expected | sarcoma | Abramson Cancer Center at Penn Medicine | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT07250854 | Jan 2026 → Mar 2027 expected | biliary atresia | University of Alabama at Birmingham | Recruiting | No outcome recorded |
| Phase 0 | NCT07295262 | Jan 2026 → Jul 2028 expected | adult hepatocellular carcinoma | West China Hospital | Recruiting | No outcome recorded |
| Phase 0 | NCT06446648 | Jul 2024 → Jul 2028 expected | prostate adenocarcinoma | University of California, Irvine | Recruiting | No outcome recorded |
| Phase 0 | NCT05645523 | Oct 2023 → Dec 2026 expected | cancer | St. Jude Children's Research Hospital | Recruiting | No outcome recorded |
| Phase 0 | NCT05859971 | Apr → Jun 2023 | breast cancer | University of Wisconsin, Madison | Completed | No outcome recorded |
| Phase 0 | NCT05087264 | Mar 2022 → Oct 2025 | cervical carcinoma | Fifth Affiliated Hospital, Sun Yat-Sen University | Unknown | No outcome recorded |
| Phase 0 | NCT05075889 | Nov 2021 → Apr 2022 | bone benign neoplasm | Dartmouth-Hitchcock Medical Center | Completed | No outcome recorded |
| Phase 0 | NCT06579430 | Nov 2020 → May 2024 | hypoparathyroidism | University Medical Center Groningen | Completed | No outcome recorded |
| Phase 0 | NCT04051502 | Aug 2019 → Dec 2025 | ovarian cancer | Memorial Sloan Kettering Cancer Center | Completed | No outcome recorded |
| Phase 0 | NCT03430934 | Jul 2018 → Aug 2019 | skin cancer | University of Missouri-Columbia | Completed | No outcome recorded |
| Phase 0 | NCT03850158 | Jan 2017 → Nov 2019 | endometriosis | Insel Gruppe AG, University Hospital Bern | Completed | No outcome recorded |
| Phase 0 | NCT02405559 | May → Dec 2015 | — | Centre Hospitalier Universitaire Saint Pierre | Unknown | No outcome recorded |
| Phase 0 | NCT01962649 | Oct 2013 → Apr 2014 | hepatocellular carcinoma | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 0 | NCT01796041 | Jul 2011 → Nov 2016 | invasive ductal breast carcinoma, invasive lobular breast carcinoma | Abramson Cancer Center at Penn Medicine | Completed | No outcome recorded |
| Phase 0 | NCT01204554 | Sep 2008 → Dec 2010 | — | Oslo University Hospital | Unknown | No outcome recorded |
| Phase 133 trials | ||||||
| Phase 1 | NCT05038098 | Mar 2026 → Feb 2027 expected | gastric adenocarcinoma | M.D. Anderson Cancer Center | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT07254845 | Dec 2025 → May 2026 overdue | brain neoplasm | VPIX Medical | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06867978 | Jun 2025 → Jun 2026 overdue | brain neoplasm | VPIX Medical | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06994949 | Jan 2025 → Jan 2029 expected | hydrocephalus | Eva Sevick | Recruiting | No outcome recorded |
| Phase 1 | NCT05946837 | Aug → Sep 2023 | spondylosis, cervical | The University of Texas Health Science Center, Houston | Completed | No outcome recorded |
| Phase 1 | NCT05746104 | Mar 2023 → Feb 2027 expected | nervous system neoplasm | Abramson Cancer Center at Penn Medicine | Enrolling by invitation | No outcome recorded |
| Phase 1 | NCT05197530 | Dec 2021 → Jun 2026 overdue | rheumatoid arthritis | University of Rochester | Recruiting | No outcome recorded |
| Phase 1 | NCT04340752 | Jan 2021 → Sep 2025 | rotator cuff syndrome | NYU Langone Health | Completed | No outcome recorded |
| Phase 1 | NCT04833569 | Sep 2020 → Feb 2021 | periodontitis | King Saud University | Completed | No outcome recorded |
| Phase 1 | NCT04393168 | May → Jun 2020 | lymphedema | Nicole Lindenblatt | Completed | No outcome recorded |
| Phase 1 | NCT04084067 | Feb 2020 → Jul 2026 | neoplasm | St. Jude Children's Research Hospital | Completed | No outcome recorded |
| Phase 1 | NCT04046146 | Dec 2019 → Mar 2020 | rheumatoid arthritis | University of Rochester | Completed | No outcome recorded |
| Phase 1 | NCT04173676 | Dec 2019 → Nov 2021 | — | Fifth Affiliated Hospital, Sun Yat-Sen University | Unknown | No outcome recorded |
| Phase 1 | NCT02570958 | Oct 2017 | non-small cell lung carcinoma | St. Joseph's Healthcare Hamilton | Withdrawn | No outcome recorded Stop: Business |
| Phase 1 | NCT02949726 | Apr 2017 → Oct 2022 | lymphedema | The University of Texas Health Science Center, Houston | Completed | No outcome recorded |
| Phase 1 | NCT03793322 | Jan 2017 → Jan 2020 | hepatocellular carcinoma | Zhujiang Hospital | Unknown | No outcome recorded |
| Phase 1 | NCT02570815 | Oct 2016 → Oct 2026 expected | non-small cell lung carcinoma | St. Joseph's Healthcare Hamilton | Recruiting | No outcome recorded |
| Phase 1 | NCT02840617 | Mar 2016 → Dec 2018 | prostate cancer | Third Affiliated Hospital, Sun Yat-Sen University | Unknown | No outcome recorded |
| Phase 1 | NCT02680067 | Dec 2015 → Jul 2022 | rheumatoid arthritis | University of Rochester | Completed | No outcome recorded |
| Phase 1 | NCT02611245 | Aug 2015 → Oct 2016 | esophageal cancer, lung cancer | Chinese Academy of Sciences | Completed | No outcome recorded |
| Phase 1 | NCT03262636 | Jun 2015 → Mar 2020 | brain cancer, primary brain neoplasm | University of Pennsylvania | Completed | No outcome recorded |
| Phase 1 | NCT02621268 | Nov 2014 → Nov 2016 | neoplasm | University of Pennsylvania | Completed | No outcome recorded |
| Phase 1 | NCT02119858 | Jul 2014 → Feb 2018 | prostate carcinoma | City of Hope Medical Center | Completed | No outcome recorded |
| Phase 1 | NCT02111824 | Jan 2014 → Nov 2019 | lung neoplasm | The Methodist Hospital Research Institute | Terminated | No outcome recorded Stop: Enrollment |
| Phase 1 | NCT02280954 | Nov 2013 → Feb 2017 | neoplasm | University of Pennsylvania | Completed | No outcome recorded |
| Phase 1 | NCT01873716 | May 2013 → Jan 2016 | atherosclerosis, carotid stenosis | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 1 | NCT01884584 | Jun 2012 → Jan 2015 | cancer | Emory University | Completed | No outcome recorded |
| Phase 1 | NCT01281488 | Oct 2011 → Oct 2017 | renal cell carcinoma | City of Hope Medical Center | Completed | No outcome recorded |
| Phase 1 | NCT01295931 | Feb 2011 → Oct 2014 | melanoma | M.D. Anderson Cancer Center | Completed | No outcome recorded |
| Phase 1 | NCT01121718 | Sep 2010 → Apr 2012 | melanoma | Dana-Farber Cancer Institute | Completed | No outcome recorded |
| Phase 1 | NCT01095913 | Mar 2010 → Jan 2014 | female breast carcinoma | M.D. Anderson Cancer Center | Completed | No outcome recorded |
| Phase 1 | NCT00264602 | Feb 2009 → Sep 2017 overdue | lung cancer | Dana-Farber Cancer Institute | Active not recruiting | No outcome recorded |
| Phase 1 | NCT00453050 | Mar 2006 → Mar 2009 | cutaneous melanoma, metastatic malignant neoplasm | University of Oklahoma | Completed | No outcome recorded |
| Phase 1/218 trials | ||||||
| Phase 1/2 | NCT07108855 | Sep 2025 → Jun 2027 expected | carcinoma of esophagus, gastric carcinoma | University Medical Center Groningen | Recruiting | No outcome recorded |
| Phase 1/2 | NCT06647901 | Aug 2024 → Aug 2026 overdue | bone giant cell tumor | Tang Xiaodong | Recruiting | No outcome recorded |
| Phase 1/2 | NCT04723810 | Aug 2024 → Jan 2027 expected | — | University of Pennsylvania | Recruiting | No outcome recorded |
| Phase 1/2 | NCT07513038 | Aug 2024 → Aug 2026 overdue | biliary atresia | Boston Children's Hospital | Recruiting | No outcome recorded |
| Phase 1/2 | NCT05808140 | Apr 2023 → Dec 2025 | lumbar disk disease | Zhongnan Hospital | Completed | No outcome recorded |
| Phase 1/2 | NCT03953144 | Dec 2022 → Sep 2026 overdue | non-small cell lung carcinoma | St. Joseph's Healthcare Hamilton | Recruiting | No outcome recorded |
| Phase 1/2 | NCT05092750 | Sep 2021 → Aug 2023 | colorectal cancer | M.D. Anderson Cancer Center | Withdrawn | No outcome recorded Stop: Enrollment |
| Phase 1/2 | NCT05346380 | Oct 2020 → Jun 2025 | esophageal disorder, lung neoplasm | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 1/2 | NCT03745690 | Dec 2018 → Jun 2021 | head and neck carcinoma | Jonsson Comprehensive Cancer Center | Withdrawn | No outcome recorded Stop: Enrollment |
| Phase 1/2 | NCT03292757 | Dec 2017 → Aug 2018 | esophageal cancer | Oxford University Hospitals NHS Trust | Completed | No outcome recorded |
| Phase 1/2 | NCT03204994 | Aug 2017 → Jul 2018 | lymph node disorder, rectal cancer | Oxford University Hospitals NHS Trust | Terminated | No outcome recorded Stop: Enrollment |
| Phase 1/2 | NCT03204201 | Jul 2017 → Jul 2018 | rectal cancer, urethral disorder | Oxford University Hospitals NHS Trust | Terminated | No outcome recorded |
| Phase 1/2 | NCT03097627 | Feb → Oct 2016 | pulmonary coin lesion | Brigham and Women's Hospital | Completed | No outcome recorded |
| Phase 1/2 | NCT02710240 | Jun 2015 → Feb 2020 | central nervous system neoplasm | Abramson Cancer Center at Penn Medicine | Completed | No outcome recorded |
| Phase 1/2 | NCT03097575 | Jan 2015 → Jan 2027 expected | lymph node adenoid cystic carcinoma | Massachusetts General Hospital | Recruiting | No outcome recorded |
| Phase 1/2 | NCT01834469 | Mar 2013 → Oct 2014 | ovarian cancer, peritoneal carcinomatosis | Jules Bordet Institute | Completed | No outcome recorded |
| Phase 1/2 | NCT01993576 | Jan 2013 → Sep 2014 | breast cancer | Jules Bordet Institute | Completed | No outcome recorded |
| Phase 1/2 | NCT00540982 | Feb 1997 → May 2010 | lung cancer | City of Hope Medical Center | Completed | No outcome recorded |
| Phase 229 trials · 1 missed | ||||||
| Phase 2 | NCT07650656 | May 2027 → May 2028 expected | sarcoma | City of Hope Medical Center | Recruiting | No outcome recorded |
| Phase 2 | NCT07149207 | May 2026 → Apr 2028 expected | head and neck squamous cell carcinoma | Medical University of South Carolina | Recruiting | No outcome recorded |
| Phase 2 | NCT07518485 | Apr 2026 → Mar 2027 expected | head and neck cancer, oral cavity cancer | Centre Hospitalier Universitaire Vaudois | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07316023 | Jan → Jun 2026 overdue | chronic periodontitis | Nada Mahmoud Soliman | Recruiting | No outcome recorded |
| Phase 2 | NCT07060443 | Jul 2025 → Dec 2028 expected | — | Pusan National University Yangsan Hospital | Recruiting | No outcome recorded |
| Phase 2 | NCT05687617 | Dec 2022 → Mar 2024 | gastric adenocarcinoma, peritoneal carcinomatosis | Laval University | Terminated | No outcome recorded Stop: Enrollment |
| Phase 2 | NCT04752137 | May 2022 → Apr 2028 expected | benign neoplasm, cancer | Massachusetts General Hospital | Recruiting | No outcome recorded |
| Phase 2 | NCT04891185 | Oct 2021 → Oct 2023 | ovarian cancer | Universitaire Ziekenhuizen KU Leuven | Terminated | No outcome recorded |
| Phase 2 | NCT04942665 | Sep 2021 → Sep 2022 | cholecystitis, hepatocellular carcinoma | University of Florida | Completed | No outcome recorded |
| Phase 2 | NCT04973475 | Jul 2021 → Jul 2023 overdue | gastric carcinoma | Fujian Medical University | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT04719156 | Mar 2021 → Dec 2026 expected | sarcoma | Kurt Weiss | Recruiting | No outcome recorded |
| Phase 2 | NCT04511026 | Jan → Jun 2021 | endometrial cancer | Stanford University | Terminated | Missed primary |
| Phase 2 | NCT04842162 | Dec 2020 → Nov 2026 expected | head and neck cancer | Gustave Roussy, Cancer Campus, Grand Paris | Recruiting | No outcome recorded |
| Phase 2 | NCT03050879 | Oct 2017 → Jul 2019 | gastric neoplasm | Fujian Medical University | Completed | No outcome recorded |
| Phase 2 | NCT02775838 | Apr 2016 → Dec 2018 | — | University Hospital Erlangen | Completed | No outcome recorded |
| Phase 2 | NCT02817334 | Mar → Sep 2016 | breast cancer | National Cancer Center, Korea | Unknown | No outcome recorded |
| Phase 2 | NCT03332004 | Jan 2016 → Feb 2017 | endometriosis of pelvic peritoneum | Catholic University of the Sacred Heart | Completed | No outcome recorded |
| Phase 2 | NCT03935165 | Jan 2016 → May 2019 | endometriosis | Catholic University of the Sacred Heart | Completed | No outcome recorded |
| Phase 2 | NCT03811704 | Jan 2016 → Dec 2021 | — | Zhujiang Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT02473159 | Mar → Dec 2015 | breast cancer | National Cancer Center, Korea | Unknown | No outcome recorded |
| Phase 2 | NCT03012750 | Feb 2015 → Aug 2016 | peripheral arterial disease | University Hospital Erlangen | Completed | No outcome recorded |
| Phase 2 | NCT02027818 | Jan → Oct 2014 | breast cancer | Jules Bordet Institute | Completed | No outcome recorded |
| Phase 2 | NCT02027831 | Dec 2013 → Oct 2014 | head and neck cancer | Jules Bordet Institute | Unknown | No outcome recorded |
| Phase 2 | NCT02032563 | Dec 2013 → Oct 2014 | breast cancer | Jules Bordet Institute | Unknown | No outcome recorded |
| Phase 2 | NCT02032498 | Jul 2013 → Oct 2014 | breast cancer | Jules Bordet Institute | Unknown | No outcome recorded |
| Phase 2 | NCT01662752 | May 2013 → Sep 2015 | colorectal cancer | Imperial College London | Completed | No outcome recorded |
| Phase 2 | NCT02032485 | Mar 2013 → Sep 2014 | colorectal cancer, peritoneal carcinomatosis | Jules Bordet Institute | Completed | No outcome recorded |
| Phase 2 | NCT02043340 | Oct 2012 → Jul 2013 | chronic periodontitis | SVS Institute of Dental Sciences | Completed | No outcome recorded |
| Phase 2 | NCT01771666 | Jul 2012 → Mar 2015 | breast cancer | Stanford University | Completed | No outcome recorded |
| Phase 2/34 trials | ||||||
| Phase 2/3 | NCT05926856 | Aug → Dec 2023 | bile duct disorder | Zhujiang Hospital | Completed | No outcome recorded |
| Phase 2/3 | NCT04857346 | Jun → Dec 2020 | chronic periodontitis, prediabetes syndrome, type 2 diabetes mellitus | King Saud University | Completed | No outcome recorded |
| Phase 2/3 | NCT02910726 | Sep 2016 → Sep 2022 | childhood malignant neoplasm | Memorial Sloan Kettering Cancer Center | Completed | No outcome recorded |
| Phase 2/3 | NCT01693484 | Apr 2013 → Mar 2015 | — | Louisiana State University Health Sciences Center Shreveport | Terminated | No outcome recorded |
| Phase 313 trials · 2 missed | ||||||
| Phase 3 | NCT07406815 | Jun → Jul 2026 overdue | esophageal cancer | Fujian Medical University Union Hospital | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07303231 | Jan 2026 → Aug 2027 expected | esophageal cancer | Fujian Medical University Union Hospital | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06755554 | Jan 2025 → Jan 2026 overdue | gastric carcinoma | Ukrainian Society of Clinical Oncology | Recruiting | No outcome recorded |
| Phase 3 | NCT05117853 | Nov 2021 → Oct 2024 | hypoparathyroidism, thyroid gland disorder | Onze Lieve Vrouw Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT04785443 | Jun 2021 → Jun 2026 overdue | thyroid gland disorder | University Hospital, Brest | Recruiting | No outcome recorded |
| Phase 3 | NCT04904081 | Jun 2021 → Jun 2024 | Hirschsprung disease, anorectal malformation | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Unknown | No outcome recorded |
| Phase 3 | NCT04611997 | Nov 2020 → Oct 2026 expected | gastric cancer, metastatic malignant neoplasm in the lymph nodes | Fujian Medical University | Active not recruiting | No outcome recorded |
| Phase 3 | NCT04712032 | Jul 2020 → Jul 2022 | Crohn disease, colorectal carcinoma | Leiden University Medical Center | Unknown | Missed primary |
| Phase 3 | NCT04219332 | Dec 2019 → Nov 2020 | gastric cancer | Fujian Medical University | Unknown | Missed primary |
| Phase 3 | NCT02997553 | Nov 2017 → Sep 2022 | anus cancer, breast carcinoma, cervical carcinoma, cutaneous melanoma +5 | Institut de Cancérologie de Lorraine | Completed | No outcome recorded |
| Phase 3 | NCT03294330 | Oct 2017 → Sep 2021 | breast cancer, cutaneous melanoma | Milton S. Hershey Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT02279108 | Nov 2014 → May 2016 | breast neoplasm | University Hospital of Saint-Etienne | Completed | No outcome recorded |
| Phase 3 | NCT02260349 | Apr 2014 → Feb 2016 | prostate neoplasm | University Hospital of Saint-Etienne | Withdrawn | No outcome recorded |
| Phase 424 trials | ||||||
| Phase 4 | NCT07635420 | Sep 2026 → Jan 2029 expected | head and neck cancer | Region Skane | Recruiting | No outcome recorded |
| Phase 4 | NCT07195331 | Feb → Nov 2026 expected | — | Instituto de Investigación Biomédica de Salamanca | Recruiting | No outcome recorded |
| Phase 4 | NCT07315828 | Jan → Dec 2026 expected | bone giant cell tumor | Shanghai Jiao Tong University Affiliated Sixth People's Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT07315841 | Jan → Dec 2026 expected | tenosynovial giant cell tumor | Shanghai Jiao Tong University Affiliated Sixth People's Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT07144904 | Oct 2025 → Feb 2026 overdue | endometriosis of pelvic peritoneum, ovarian endometriosis | Baylor College of Medicine | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06871787 | Sep 2025 → Sep 2027 expected | cervical cancer, endometrial cancer, intestinal perforation, ovarian cancer +1 | Istanbul University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06164392 | Dec 2024 | neuroma | Northwestern University | Withdrawn | No outcome recorded Stop: Enrollment |
| Phase 4 | NCT06169735 | Apr 2024 → May 2026 | parathyroid gland adenoma | University of Alabama at Birmingham | Terminated | No outcome recorded Stop: Business |
| Phase 4 | NCT06258486 | Feb 2024 → Feb 2026 | lymphocele, prostate cancer | Kaiser Permanente | Unknown | No outcome recorded |
| Phase 4 | NCT06398028 | Aug 2023 → Mar 2026 overdue | liver and intrahepatic bile duct neoplasm | Hospital Universitari Vall d'Hebron Research Institute | Recruiting | No outcome recorded |
| Phase 4 | NCT05960149 | Jul 2023 → Dec 2025 | prostate adenocarcinoma | Ankara University | Unknown | No outcome recorded |
| Phase 4 | NCT06002906 | Jan 2023 → Jul 2027 expected | gastric ulcer, morbid obesity | University Health Network, Toronto | Active not recruiting | No outcome recorded |
| Phase 4 | NCT05419947 | Jun 2022 → May 2023 | gallbladder disorder | Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León | Completed | No outcome recorded |
| Phase 4 | NCT05354856 | Mar 2022 → Dec 2023 | gastric cancer | Rigshospitalet, Denmark | Terminated | No outcome recorded Stop: Enrollment |
| Phase 4 | NCT04591028 | Jan 2022 | gastric cancer | Mayo Clinic | Withdrawn | No outcome recorded Stop: Business |
| Phase 4 | NCT04854018 | Apr 2021 → Sep 2022 | Ewing sarcoma, childhood kidney neoplasm, osteosarcoma, rhabdomyosarcoma | Birmingham Women's and Children's NHS Foundation Trust | Completed | No outcome recorded |
| Phase 4 | NCT04624841 | Jan → Dec 2021 | acute cholecystitis | Hamad Medical Corporation | Unknown | No outcome recorded |
| Phase 4 | NCT04882618 | Nov 2019 → Nov 2021 | metastatic malignant neoplasm in the lymph nodes, prostate cancer | TC Erciyes University | Unknown | No outcome recorded |
| Phase 4 | NCT03969108 | Aug → Nov 2019 | Graves disease, thyroid cancer | University Health Network, Toronto | Completed | No outcome recorded |
| Phase 4 | NCT03584633 | Apr → Sep 2019 | lymphedema | University of Iowa | Completed | No outcome recorded |
| Phase 4 | NCT03080558 | Aug 2017 → Feb 2019 | endometriosis | University Hospital, Clermont-Ferrand | Unknown | No outcome recorded |
| Phase 4 | NCT03155464 | Jun 2017 → Jan 2018 | systemic sclerosis | Duke University | Withdrawn | No outcome recorded |
| Phase 4 | NCT04012476 | Nov 2016 → Mar 2020 | hypoparathyroidism | Hospital Son Espases | Unknown | No outcome recorded |
| Phase 4 | NCT02781259 | May 2016 → Feb 2017 | breast neoplasm | Samsung Medical Center | Unknown | No outcome recorded |
| Phase not applicable43 trials · 1 met primary · 1 missed | ||||||
| — | NCT07808957 | Oct → Dec 2026 expected | — | Research Inc | Not yet recruiting | No outcome recorded |
| — | NCT07593339 | Jun 2026 → Dec 2027 expected | malignant epithelial tumor of ovary | Başakşehir Çam & Sakura City Hospital | Not yet recruiting | No outcome recorded |
| — | NCT07638956 | Jun 2026 → Sep 2027 expected | colon carcinoma | Tanta University | Not yet recruiting | No outcome recorded |
| — | NCT07146295 | Apr 2025 → Jul 2026 overdue | breast cancer, metastatic malignant neoplasm in the lymph nodes | Isabelle Henskens | Recruiting | No outcome recorded |
| — | NCT07551388 | Jan → Apr 2025 | acute cholecystitis | Peking Union Medical College Hospital | Completed | No outcome recorded |
| — | NCT06840418 | Jan 2025 → Dec 2027 expected | cervical cancer | Obstetrics & Gynecology Hospital of Fudan University | Recruiting | No outcome recorded |
| — | NCT06347354 | Sep 2024 → Aug 2025 | breast cancer | Centro di Riferimento Oncologico - Aviano | Unknown | No outcome recorded |
| — | NCT06421103 | Jun 2024 → Aug 2028 expected | digestive system disorder | Great Ormond Street Hospital for Children NHS Foundation Trust | Recruiting | No outcome recorded |
| — | NCT06227338 | Feb 2024 → Jan 2026 overdue | breast cancer | Jules Bordet Institute | Recruiting | No outcome recorded |
| — | NCT06222645 | Nov 2023 → Apr 2026 overdue | colorectal cancer, gastric cancer | Saint Petersburg State University, Russia | Recruiting | No outcome recorded |
| — | NCT05206279 | Jun 2023 → Sep 2024 | endometriosis | Insel Gruppe AG, University Hospital Bern | Completed | No outcome recorded |
| — | NCT05830890 | May 2023 → Dec 2025 | rectal cancer | National Cancer Center, China | Unknown | No outcome recorded |
| — | NCT05735964 | Mar 2023 → Mar 2026 overdue | esophageal atresia/tracheoesophageal fistula | Birmingham Women's and Children's NHS Foundation Trust | Recruiting | No outcome recorded |
| — | NCT05094102 | May 2022 → Apr 2023 | breast cancer, lymphedema | University of Wisconsin, Madison | Completed | No outcome recorded |
| — | NCT05228587 | Feb 2022 → Sep 2024 | hepatobiliary disorder | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Unknown | No outcome recorded |
| — | NCT05160740 | Sep 2021 → Dec 2022 | liver cancer | Zhujiang Hospital | Unknown | No outcome recorded |
| — | NCT04615806 | Sep 2020 → Sep 2022 | esophageal cancer | Fujian Medical University Union Hospital | Unknown | No outcome recorded |
| — | NCT04020939 | Mar 2020 → Mar 2021 | Hirschsprung disease, gastroschisis, intestinal atresia, intestinal perforation +4 | St. Justine's Hospital | Completed | No outcome recorded |
| — | NCT03854890 | Jul 2019 → Apr 2020 | rectal cancer | Fudan University | Unknown | No outcome recorded |
| — | NCT03941756 | Aug 2018 → Jan 2027 expected | female breast carcinoma, inflammatory breast carcinoma, melanoma | M.D. Anderson Cancer Center | Recruiting | No outcome recorded |
| — | NCT06379438 | Mar 2018 → Mar 2019 | aphthous stomatitis, ulcerative stomatitis | Yuzuncu Yil University | Completed | No outcome recorded |
| — | NCT03579979 | Aug 2017 → Aug 2019 | breast cancer | Chinese Academy of Sciences | Completed | No outcome recorded |
| — | NCT02994225 | Mar 2017 → Jun 2019 | breast cancer | Gustave Roussy, Cancer Campus, Grand Paris | Completed | No outcome recorded |
| — | NCT02920216 | Dec 2016 → Aug 2017 | head and neck cancer | Institut de Cancérologie de Lorraine | Completed | No outcome recorded |
| — | NCT02669485 | Jan 2016 → Jun 2017 | intestinal perforation | The University of Hong Kong | Unknown | No outcome recorded |
| — | NCT02344654 | May 2015 → Aug 2018 | cholecystitis, gallstones | Hvidovre University Hospital | Completed | Met primary |
| — | NCT02478138 | May 2015 → Jan 2024 | head and neck neoplasm | University Health Network, Toronto | Completed | No outcome recorded |
| — | NCT02423148 | May 2015 → Nov 2016 | lung cancer | Dana-Farber Cancer Institute | Withdrawn | No outcome recorded Stop: Enrollment |
| — | NCT02117310 | Mar → Nov 2015 | skull base neoplasm | Ohio State University | Completed | No outcome recorded |
| — | NCT02415725 | Sep 2014 → Dec 2017 | breast cancer, lymph node disorder | Centre Hospitalier Universitaire Saint Pierre | Unknown | No outcome recorded |
| — | NCT02057393 | Jun 2014 → Jan 2016 | melanoma | Milton S. Hershey Medical Center | Completed | No outcome recorded |
| — | NCT02142244 | May 2014 → Dec 2018 | melanoma, metastatic malignant neoplasm in the lymph nodes | Barretos Cancer Hospital | Unknown | No outcome recorded |
| — | NCT02084784 | Jan 2014 → Sep 2015 | breast cancer, lymph node adenoid cystic carcinoma | Chinese Academy of Sciences | Completed | No outcome recorded |
| — | NCT01898403 | Jun 2013 → Jun 2014 | melanoma | Stanford University | Completed | No outcome recorded |
| — | NCT01737619 | Apr 2013 → Apr 2025 overdue | endometrial clear cell adenocarcinoma, endometrial endometrioid adenocarcinoma, endometrial mixed adenocarcinoma, endometrial serous adenocarcinoma +1 | M.D. Anderson Cancer Center | Active not recruiting | No outcome recorded |
| — | NCT02070640 | Jan 2013 → Aug 2014 | cholecystitis | Ohio State University | Completed | No outcome recorded |
| — | NCT02516319 | Sep 2012 → Jan 2016 | liver failure | Cardiox Corporation | Terminated | No outcome recorded Stop: Business |
| — | NCT01673022 | May 2012 → Jan 2017 | cervical cancer, endometrial cancer | Indiana University | Completed | No outcome recorded |
| — | NCT01410734 | Jul 2011 → Dec 2012 | gallbladder disorder, gallstones | Intuitive Surgical | Completed | No outcome recorded |
| — | NCT01424215 | Jan 2011 → Aug 2014 | cholecystitis, cholelithiasis, pancreatitis | Maimonides Medical Center | Completed | No outcome recorded |
| — | NCT01112514 | Feb → Dec 2010 | intestinal polyposis syndrome, polyp of colon | Massachusetts General Hospital | Completed | No outcome recorded |
| — | NCT01034670 | Jun 2009 → Sep 2017 | gastric cancer, gastrointestinal stromal tumor | Stanford University | Terminated | No outcome recorded Stop: Business |
| — | NCT00376857 | — | cataract | University of Regensburg | Completed | Missed primary |
| Comparator or background therapy24 trials | ||||||
| Phase 0 | NCT07613931 Background | Jul → Sep 2026 overdue | lymphedema | Tactile Medical | Recruiting | No outcome recorded |
| Phase 0 | NCT02851368 Background | Nov 2016 → Nov 2017 | pulmonary coin lesion | University of Pittsburgh | Completed | No outcome recorded |
| Phase 0 | NCT02359578 Background | Aug → Nov 2014 | — | Centre Hospitalier Universitaire Saint Pierre | Completed | No outcome recorded |
| Phase 1 | NCT05937269 Background | Oct 2023 → Feb 2026 overdue | head and neck cancer, lymphedema | The University of Texas Health Science Center, Houston | Enrolling by invitation | No outcome recorded |
| Phase 1 | NCT06939946 Background | Sep 2023 → Aug 2025 | parathyroid gland disorder, thyroid gland disorder | OPTOSURGICAL, LLC | Terminated | No outcome recorded Stop: Business |
| Phase 1 | NCT02070627 Background | Jul 2013 → Aug 2014 | acute cholecystitis | Ohio State University | Completed | No outcome recorded |
| Phase 1/2 | NCT02946021 Background | Oct 2016 → Feb 2018 | head and neck cancer, lymphedema | Tactile Medical | Completed | No outcome recorded |
| Phase 2 | NCT06327490 Background | Oct 2024 → Jun 2028 expected | breast cancer | University of Florida | Recruiting | No outcome recorded |
| Phase 2 | NCT04987281 Background | Jan 2022 → Dec 2023 | non-small cell lung carcinoma | M.D. Anderson Cancer Center | Withdrawn | No outcome recorded Stop: Enrollment |
| Phase 2 | NCT05229874 Comparator | Jan 2022 → Mar 2023 | gastric cancer | Hebei Medical University | Unknown | No outcome recorded |
| Phase 2/3 | NCT04759820 Comparator | Jan 2021 → Jun 2022 | — | LI XIN-XIANG | Unknown | No outcome recorded |
| Phase 3 | NCT06845306 Comparator | Jun 2025 → Jul 2026 overdue | malignant colon neoplasm | Vadim Kuznetsov | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT05646316 Background | Dec 2022 → Oct 2026 expected | uterine cancer | NRG Oncology | Recruiting | No outcome recorded |
| Phase 3 | NCT05168839 Background | Sep 2022 → Oct 2025 overdue | colorectal cancer | Centre Hospitalier Universitaire de Besancon | Recruiting | No outcome recorded |
| Phase 3 | NCT03557827 Comparator | Mar 2018 → Dec 2019 | periodontal disorder | National Taiwan University Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT05709548 Comparator | Mar 2023 → Dec 2025 | acute cholecystitis | Corporacion Parc Tauli | Unknown | No outcome recorded |
| Phase 4 | NCT05332405 Background | May 2022 → Oct 2023 | cubital tunnel syndrome | NYU Langone Health | Withdrawn | No outcome recorded |
| Phase 4 | NCT06629415 Comparator | May 2022 → May 2023 | cholecystitis | Theodor Bilharz Research Institute | Completed | No outcome recorded |
| — | NCT06672224 Background | Aug 2025 → Aug 2026 | breast carcinoma, lymphatic system disorder | City of Hope Medical Center | Withdrawn | No outcome recorded Stop: Enrollment |
| — | NCT03572998 Background | Sep 2018 → Feb 2019 | lymphedema | University of Aarhus | Unknown | No outcome recorded |
| — | NCT04056923 Comparator | Jan → Jun 2018 | lung cancer, pulmonary coin lesion | Wen-zhao ZHONG | Completed | No outcome recorded |
| — | NCT02508298 Comparator | Apr 2014 → Jul 2018 | cirrhosis of liver, portal hypertension | VA Connecticut Healthcare System | Completed | No outcome recorded |
| — | NCT01969448 Background | Mar 2013 → Apr 2016 | ductal breast carcinoma in situ | Washington University School of Medicine | Completed | No outcome recorded |
| — | NCT00137254 Comparator | Dec 2005 → Feb 2007 | — | United States Army Institute of Surgical Research | Completed | No outcome recorded |
News releases announcing trial results or a regulatory action · 1
| Date | Issuer | Release |
|---|---|---|
| 2026-08-04 | Zydus Lifesciences Limited | Regulatory Zydus announces Final Approval from the USFDA for Indocyanine Green for Injection with 180-Days CGT exclusivity zyduslife.com ↗
Zydus Lifesciences Limited (Zydus) announces the receipt of final approval from the United States Food and Drug Administration (USFDA) for its Abbreviated New Drug Application (ANDA) for Indocyanine Green for Injection, USP, 25 mg/vial, a sterile lyophilised powder for reconstitution. |
All press releases naming this drug 1 release
| Date | Issuer | Release |
|---|---|---|
| 2026-08-04 | Zydus Lifesciences Limited | Zydus announces Final Approval from the USFDA for Indocyanine Green for Injection with 180-Days CGT exclusivity zyduslife.com ↗ |
Evidence & citations 15 cited values
Every value below carries the sentence it was read from. 213 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | indocyanine green | “The indocyanine green in 5% human albumin solution (tracer) (50 μL) will be injected intradermally in both forearms or both lower legs using MicronJet600 microneedles paying...” NCT04393168 ↗202“The purpose of this research study is to assess the feasibility of using a different dye and imaging device, indocyanine green (ICG)-fluorescent imaging through the Asimov...” NCT05859971 ↗ “Near-infrared Fluorescence Lymphatic Imaging following the off-label use of Indocyanine Green as a lymph contrast agent and the use of a custom designed fluorescence imager to...” NCT02946021 ↗ “Patients enrolled in the study will undergo peritumoral injection of near-infrared dye indocyanine green around the lung lesion or within the adjacent segmental bronchus at the...” NCT03097575 ↗ “Clinical, bacterial, and inflammatory outcomes of indocyanine green-mediated photodynamic therapy for treating periimplantitis among diabetic patients: A randomized controlled...” NCT04833569 ↗ “The intraoperative use of indocyanine green angiography has recently been described as a reliable means of detecting parathyroid and predicting the risk of postoperative...” NCT04785443 ↗ “We therefore aimed to evaluate the efficacy of real-time assessment with near-infrared (NIR) fluorescence imaging with indocyanine green (ICG) in the prevention of anastomotic leakage.” PMID 39151436 ↗ Aug 2024 “This intervention involves the intravenous injection of the fluorescent contrast agent Indocyanine Green (ICG), followed by imaging with a near-infrared fluorescence camera system.” NCT06222645 ↗ “Feasibility Study of the (Intravenously Injected) Indocyanine Green (ICG) Imaging of Tumoral Implants in Patients With Peritoneal Carcinomatosis From Ovarian Carcinoma” NCT01834469 ↗ “Intraoperative fluorescence imaging using indocyanine green has proven to be a feasible and reproducible technique for real-time perfusion assessment.” NCT06845306 ↗ “they will receive a dermal injection of indocyanine green (ICG) 0.3-1.0 ml at the melanoma tumor site or subareola if breast cancer” NCT03294330 ↗ |
| Known as | IC-Green | “Indocyanine Green (IC-Green)” NCT07108855 ↗ |
| Known as | ICG | “Several cohort studies have shown that indocyanine green (ICG) combined with fluorescent near-infrared imaging is a feasible and reproducible technique for real-time...” PMID 35365509 ↗ Apr 202278“Dosage Form: Intravenous injection Dosage: 0.1 - 0.5 mg/kg of Indocyanine Green (ICG) Frequency: Single administration during surgery Duration: Real-time imaging performed...” NCT07254845 ↗ “Because endometriosis is associated with hypervascularisation the visualization of tissue perfusion by additional use of near infrared (NIR) fluorescence imaging with...” NCT03850158 ↗ “PURPOSE: To carry out a prospective investigation of the functional and morphological outcome of idiopathic epiretinal membrane (IEM) surgery with or without the assistance of...” PMID 17186261 ↗ Dec 2006 “This study aims to look at babies having a primary or delayed primary oesophageal repair for OA with dTOF to evaluate if using Indocyanine green (ICG) and near infrared...” NCT05735964 ↗ “The purpose of this research study is to assess the feasibility of using a different dye and imaging device, indocyanine green (ICG)-fluorescent imaging through the Asimov...” NCT05859971 ↗ “Indocyanine Green (ICG) is a non-radioactive, fluorescent compound with several clinical applications including angiography for ophthalmologic testing, visualization during...” NCT07513038 ↗ “a special type of fluorescent dye called indocyanine green (ICG) during surgery can help surgeons find the lymph nodes that the cancer is most likely to have spread to in...” NCT05092750 ↗ “Indocyanine green (ICG), administered intravenously at a dose of 2.5 mg/ml, will be used during surgery to evaluate bowel anastomosis perfusion through near-infrared...” NCT06871787 ↗ “This intervention involves the intravenous injection of the fluorescent contrast agent Indocyanine Green (ICG), followed by imaging with a near-infrared fluorescence camera system.” NCT06222645 ↗ “Background Near-infrared fluorescence guided surgery with indocyanine green (ICG) was introduced for parathyroid perfusion assessment during total thyroidectomy in 2016.” NCT06579430 ↗ |
| Known as | ICG Dye | “Drug: ICG Dye” NCT02516319 ↗ |
| Known as | indocyanine green (IC-Green). | “indocyanine green (IC-Green).” NCT02111824 ↗ |
| Known as | Indocyanine green (ICG) | “Indocyanine green (ICG)” NCT05419947 ↗ |
| Known as | Indocyanine Green Dye | “2.0 mg/kg ICG (Indocyanine Green Dye) as per standard protocol” NCT04719156 ↗ |
| Known as | INFRACYANINE | “indocyanine green (INFRACYANINE© 25mg/10mL).” NCT04842162 ↗ |
| Known as | Perio green | “Indocyanine green (Perio green, Elexxion AG, Radolfzell, Germany) prepared and applied according to manufacturer's instructions steps (mixing, application, soaking phase,...” NCT06379438 ↗ |
| Known as | PULSION | “0.25 mg /(kg BW) Indocyanine Green PULSION® - PULSION Medical Systems were administered intravenously” NCT03332004 ↗1“0.25 mg /(kg BW) Indocyanine Green PULSION®/ VERDYE Diagnostic Green®” NCT03935165 ↗ |
| Known as | SWIG | “More recently, we described Second Window Indocyanine Green (SWIG) which targets neoplastic tissue through enhanced vascular permeability.” PMID 32514886 ↗ Oct 2020 |
| Known as | TumorGlow | “Subjects will undergo infusion of 5 mg/kg indocyanine green, ICG ("TumorGlow") intravenously up to 5-days prior to surgery.” NCT07658768 ↗ |
| Known as | VERDYE Diagnostic Green | “0.25 mg /(kg BW) Indocyanine Green PULSION®/ VERDYE Diagnostic Green®” NCT03935165 ↗ |
| Modality | Diagnostic / imaging agent | “near-infrared-guided detection of tumor-specific sentinel lymph nodes” NCT00264602 ↗ |
| Route | Intravenous | “IV administration of ICG” NCT00137254 ↗ |