drugset / Trial / NCT02508298
Surrogate Markers of Portal Pressure
Non-randomizedSingle-groupOpen-labelDiagnostic
Summary
This is a prospective longitudinal study that will evaluate if changes (pre and post therapy) in indocyanine green (ICG) retention test and liver stiff ness (LS) and spleen stiffness (SS) as measured by acoustic radiofrequency impulse (ARFI) correlate with changes in portal pressure as determined by the hepatic vein pressure gradient (HVPG) in patients with compensated hepatitis C virus (HCV) cirrhosis undergoing antiviral therapy.
Timeline
- Start
- 2014-04
- Primary completion
- 2018-07
- Completion
- 2019-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Indocyanine Green | Diagnostic / imaging agent | 0.5 mg/kg | Intravenous |