drugset / Trial / NCT02508298

Surrogate Markers of Portal Pressure

NCT02508298

Completed 41 enrolled VA Connecticut Healthcare System
Non-randomizedSingle-groupOpen-labelDiagnostic

Summary

This is a prospective longitudinal study that will evaluate if changes (pre and post therapy) in indocyanine green (ICG) retention test and liver stiff ness (LS) and spleen stiffness (SS) as measured by acoustic radiofrequency impulse (ARFI) correlate with changes in portal pressure as determined by the hepatic vein pressure gradient (HVPG) in patients with compensated hepatitis C virus (HCV) cirrhosis undergoing antiviral therapy.

Timeline

Start
2014-04
Primary completion
2018-07
Completion
2019-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Indocyanine Green Diagnostic / imaging agent 0.5 mg/kg Intravenous