NIR Fluorescence Imaging of Lymphatic Transport Using ICG

Phase 1 Completed 23 enrolled University of Rochester National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · collab National Institutes of Health (NIH) · collab

Non-randomizedSingle-groupOpen-labelBasic science

Summary

In this phase 1 study, the lymphatic transport will be examined using Near InfraRed Indocyanine Green fluorescence imaging (NIR-ICG) of the upper extremities in healthy individuals using a MultiSpectral Imaging System (MSImager).

Timeline

Start: 2015-12-08
Primary completion: 2022-07
Completion: 2022-07

Publications

Rahimi H, Bell R, Bouta EM, Wood RW, Xing L, Ritchlin CT, Schwarz EM. Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential. Arthritis Res Ther. 2016 Sep 1;18:194. doi: 10.1186/s13075-016-1092-0.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Indocyanine Green	Diagnostic / imaging agent	0.1 ml	Intrathecal
Subject	Indocyanine Green	Diagnostic / imaging agent	0.1 mg/ml	Intrathecal

NIR Fluorescence Imaging of Lymphatic Transport Using ICG

Summary

Timeline

Publications

Drugs

Indications