drugset
drugset / Trial / NCT07299630

Blocking Sphenopalatine Ganglion by Intranasal Lidocaine Spray in Partial Turbinectomy Surgeries

NCT07299630 ↗

Phase 3 Completed 50 enrolled Ain Shams University
RandomizedParallel-groupTriple-blindPrevention

Summary

Nasal turbinectomy surgeries are usually done as day case surgeries as most patients are young with unremarkable comorbidities. However, considerations are still present towards patients of old age or those suffering from obesity or obstructive sleep apnea (OSA). Different techniques are still evolving to improve handling those patients to decrease complications, enhance recovery after surgery and increase patient satisfaction. Targeting sphenopalatine ganglion block by topical local anesthesia is a proposed technique that could help by decreasing peri-operative opioid consumption.

Timeline

Start
2025-12-20
Primary completion
2026-05-25
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Lidocaine Other / unclassified 3 mg/kg Intranasal
Subject Lidocaine Other / unclassified 10 % Intranasal
Background Acetaminophen Small molecule 1 g Intravenous
Background Acetaminophen Small molecule 1 g —
Background Fentanyl Other / unclassified 2 ug/kg Intravenous
Background Fentanyl Other / unclassified 50 ug Intravenous
Background Ketorolac Other / unclassified 30 mg Intravenous
Background Ketorolac Other / unclassified 30 mg —
Background Meperidine Unknown 50 mg Intravenous
Background Meperidine Unknown 50 mg —
Background Morphine Other / unclassified 0.05 mg/kg Intravenous
Background Morphine Other / unclassified 0.05 mg/kg —
Background Propofol Small molecule 1.5 mg/kg —
Background Rocuronium Other / unclassified 0.6 mg/kg —
Background Sevoflurane Other / unclassified — —
Background Xylometazoline Small molecule — Intranasal
Background Xylometazoline Small molecule — —

Indications

No indication recorded.