Pharmacokinetics and Adhesion of Lidocaine Topical System 1.8% With Water Exposure

Phase 1 Completed 24 enrolled Scilex Pharmaceuticals, Inc.

RandomizedCrossoverOpen-labelTreatment

Summary

The objectives of this study are to evaluate the adhesion performance and pharmacokinetics of ZTlido (lidocaine topical system) 1.8% during swimming, showering, and under normal conditions.

Timeline

Start: 2019-08-21
Primary completion: 2019-08-31
Completion: 2019-08-31

Publications

Vought K, Greuber E, Patel K, Argoff C, Lissin D. A Randomized, Crossover, Adhesion Performance and Pharmacokinetic Study of a Lidocaine Topical System Under Conditions of Water Exposure in Healthy Subjects. J Pain Res. 2021 Aug 16;14:2459-2467. doi: 10.2147/JPR.S323789. eCollection 2021.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Lidocaine	Other / unclassified	1.8 %	Topical

Indications

No indication recorded.