drugset

drugset / Trial / NCT07361549

Localized Injection of Lidocaine Via the Middle Meningeal Artery for Headache Treatment

NCT07361549 ↗

Phase 2 Recruiting 80 enrolled Daniel A Tonetti, MD SNIS Foundation · collab Stryker Neurovascular · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

The goal of this clinical trial is to test whether injecting lidocaine into two blood vessels of the brain can help treat chronic headaches (migraines)

Timeline

Start: 2026-09-09
Primary completion: 2030-12
Completion: 2031-07

Publications

Background Koneru M, Shaikh HA, Khalife J, Syrow L, Santucci J, Ballout AA, Patel PD, Thomas AJ, Jovin TG, Tonetti DA. Localized Injection of Lidocaine and Glucocorticoid for Refractory Headache Treatment (LIGHT): A Phase 1 Clinical Trial for Safety. Stroke Vasc Interv Neurol. 2025 Oct 29;5(6):e001966. doi: 10.1161/SVIN.125.001966. eCollection 2025 Nov. No abstract available.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Lidocaine	Other / unclassified	—	Other

Indications