drugset / Trial / NCT07274254

Lidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell Disease

NCT07274254

Phase 3 Recruiting 104 enrolled Nantes University Hospital
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of the study is to determine whether adding lidocaine to standard of care in pain management during severe vaso-occlusive crisis has an effect on the cumulative opioid consumption expressed as morphine milligram equivalent.

Timeline

Start
2026-07-03
Primary completion
2028-08-03
Completion
2028-08-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Lidocaine Other / unclassified 1 mg/kg Intravenous

Indications