drugset / Trial / NCT06539637
Ketorolac Levels in Vitreous and Aqueous Samples From Patients Undergoing Combined Cataract and Pars Plana Vitrectomy Surgeries With and Without Intracameral Phenylephrine 1.0% / Ketorolac 0.3%
RandomizedParallel-groupSingle-blindTreatment
Summary
This is a clinical trial evaluating Ketorolac levels in vitreous and aqueous humor samples from patients undergoing combined cataract and pars plana vitrectomy surgeries with and without intracameral phenylephrine 1.0% / ketorolac 0.3% (OMIDRIA). Patients not receiving intracameral OMIDRIA will receive topical ketorolac prior to cataract surgery/pars plana vitrectomy.
Timeline
- Start
- 2023-09-01
- Primary completion
- 2025-11
- Completion
- 2026-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketorolac | Other / unclassified | 0.3 % | Other |
| Subject | Ketorolac | Other / unclassified | 0.5 % | Other |
| Subject | Ketorolac | Other / unclassified | 2.88 mg/ml | Other |
| Subject | Phenylephrine | Small molecule | 1 % | Other |
| Subject | Phenylephrine | Small molecule | 10.16 mg/ml | Other |