Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery

Phase 4 Completed 84 enrolled Duke University

RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to determine if the infusion of the local anesthetic ropivacaine (a numbing medicine) and the non-steroidal anti-inflammatory drug ketorolac (a pain killer similar to ibuprofen) through a catheter placed along the cesarean delivery incision, will reduce the pain experienced after cesarean section and need for narcotic pain medicine.

Timeline

Start: 2016-11
Primary completion: 2019-03
Completion: 2019-09

Publications

Barney EZ, Pedro CD, Gamez BH, Fuller ME, Dominguez JE, Habib AS. Ropivacaine and Ketorolac Wound Infusion for Post-Cesarean Delivery Analgesia: A Randomized Controlled Trial. Obstet Gynecol. 2020 Feb;135(2):427-435. doi: 10.1097/AOG.0000000000003601.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ketorolac	Other / unclassified	30 mg	Other
Subject	Ropivacaine	Other / unclassified	440 mg	Other

Indications

No indication recorded.