drugset / Trial / NCT03738904
Prospective Randomized Controlled Trial of an Enhanced Recovery Protocol for Anorectal Surgery
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of the study is to evaluate whether being randomized to an aggressive postoperative non-narcotic pain regimen that treats pain from multiple different pathways may decrease postoperative pain levels, decrease constipation, and decrease the dependency on opioid medications after anorectal surgery versus the standard of care for managing pain. This use of a more aggressive pain regimen is considered an enhanced recovery after surgery (ERAS) protocol because it is theorized to improve or "enhance" postoperative recovery by both decreasing the use of narcotics and their detrimental effects as well as increasing the benefit of using additional non-narcotic pain medication.
Timeline
- Start
- 2018-10-26
- Primary completion
- 2022-08-18
- Completion
- 2022-08-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetaminophen | Small molecule | 1000 mg | Oral |
| Subject | Gabapentin | Small molecule | 300 mg | Oral |
| Background | Ketorolac | Other / unclassified | 10 mg | Oral |
| Subject | polyethylene glycol | Other / unclassified | — | — |
| Background | Benzocaine | Small molecule | — | — |
| Background | Dexamethasone | Small molecule | — | Oral |
| Background | Ketorolac | Other / unclassified | — | Intravenous |
| Background | Oxycodone | Other / unclassified | 5 mg | Oral |