drugset / Trial / NCT01522872

Open-label Study of TH-302 and Dexamethasone With or Without Bortezomib or Pomalidomide in Subjects With Relapsed/Refractory Multiple Myeloma

NCT01522872

Phase 1/2 Unknown 98 enrolled Threshold Pharmaceuticals
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This phase 2 study is designed to evaluate the safety and tolerability activity of TH-302 and dexamethasone with or without bortezomib or pomalidomide in subjects with relapsed/refractory multiple myeloma.

Timeline

Start
2012-02
Primary completion
2016-09
Completion
2017-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Bortezomib Small molecule
Subject Dexamethasone Small molecule
Subject Evofosfamide Other / unclassified
Subject Pomalidomide Other / unclassified

Indications