drugset / Trial / NCT07588698

Epcoritamab in Combination With R-CHOP for Patients With Aggressive Non-Hodgkin Lymphoma

NCT07588698

Phase 2 Not yet recruiting 20 enrolled Mwanasha Merrill, MD
Non-randomizedSequentialOpen-labelTreatment

Summary

A Phase II, open-label, two-arm, multicenter study evaluating the combination of epcoritamab with R-CHOP chemotherapy in patients with newly diagnosed, aggressive B-cell non-Hodgkin lymphoma.

Timeline

Start
2026-07-15
Primary completion
2028-07-31
Completion
2029-07-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclophosphamide Other / unclassified
Subject Dexamethasone Small molecule Oral
Subject Doxorubicin Other / unclassified
Subject Epcoritamab Monoclonal antibody Subcutaneous
Subject Prednisolone Other / unclassified
Subject Rituximab Monoclonal antibody
Subject Vincristine Small molecule