Drugs / Cyclophosphamide
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Cyclophosphamide

also known as CTX · cytoxan · PT-Cy · CYC · NSC-26271 · Endoxan · CPM · Cyclophosphamide - Cytoxan · +30 more

Other / unclassified

Developed for
breast cancer · lymphoma · plasma cell myeloma · leukemia · myelodysplastic syndrome · neuroblastoma · diffuse large B-cell lymphoma · acute lymphoblastic leukemia
+440 more · acute myeloid leukemia · Hodgkins lymphoma · female breast carcinoma · triple-negative breast carcinoma · chronic lymphocytic leukemia/small lymphocytic lymphoma · non-Hodgkin lymphoma · graft versus host disease · chronic myeloid leukemia · mantle cell lymphoma · B-cell chronic lymphocytic leukemia · aplastic anemia · peripheral T-cell lymphoma, not otherwise specified · sarcoma · follicular lymphoma · ovarian cancer · HER2 positive breast carcinoma · lymphoblastic lymphoma · Burkitt lymphoma · plasma cell neoplasm · disease related to hematopoietic stem cell transplant · childhood malignant neoplasm · myelofibrosis · adult acute lymphoblastic leukemia · cancer · central nervous system neoplasm · myelodysplastic/myeloproliferative disease · colorectal cancer · hematopoietic and lymphoid cell neoplasm · malignant pancreatic neoplasm · sickle cell disease · acute leukemia · B-cell acute lymphoblastic leukemia · chronic myelomonocytic leukemia · HIV infectious disease · Waldenstrom macroglobulinemia · breast neoplasm · cutaneous melanoma · Her2-receptor negative breast cancer · ovarian carcinoma · systemic sclerosis · anaplastic large cell lymphoma · B-cell non-Hodgkin lymphoma · brain cancer · childhood acute lymphoblastic leukemia · Ewing sarcoma · kidney cancer · medulloblastoma · myeloproliferative neoplasm · non-small cell lung carcinoma · angioimmunoblastic T-cell lymphoma · childhood acute myeloid leukemia · Fanconi anemia · rhabdomyosarcoma · soft tissue sarcoma · breast carcinoma · cancer of unknown primary site · marginal zone lymphoma · post-transplant lymphoproliferative disease · extragonadal germ cell tumor · immunodeficiency disease · invasive breast carcinoma · juvenile myelomonocytic leukemia · large B-cell lymphoma · MALT lymphoma · melanoma · metastatic malignant neoplasm · primary peritoneal carcinoma · retinoblastoma · acute myeloid leukemia with 11q23 abnormalities · acute myeloid leukemia with t(8;21)(q22;q22) translocation · adult T-cell leukemia/lymphoma · chronic granulomatous disease · classic Hodgkin lymphoma · fallopian tube cancer · hepatocellular carcinoma · hepatosplenic T-cell lymphoma · hormone receptor-positive breast cancer · lupus nephritis · nodal marginal zone B-cell lymphoma · paroxysmal nocturnal hemoglobinuria · splenic marginal zone lymphoma · systemic lupus erythematosus · testicular germ cell tumor · thalassemia · acute biphenotypic leukemia · amyloidosis · high grade B-cell lymphoma · inflammatory breast carcinoma · large-cell immunoblastic lymphoma · leukemia, myeloid, accelerated-phase · neoplasm · osteosarcoma · primary mediastinal large B-cell lymphoma · primary myelofibrosis · prolymphocytic leukemia · refractory plasma cell neoplasm · renal cell carcinoma · small cell lung carcinoma · AL amyloidosis · alveolar rhabdomyosarcoma · atypical teratoid rhabdoid tumor · B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) · blast phase chronic myelogenous leukemia, BCR-ABL1 positive · bone marrow failure syndrome · brain neoplasm · childhood germ cell tumor · childhood medulloblastoma · head and neck cancer · high grade B-cell lymphoma with MYC and/ or BCL2 and/or BCL6 rearrangement · lung cancer · lymphoid leukemia · metastatic melanoma · microscopic polyangiitis · multiple sclerosis · myelodysplastic/myeloproliferative neoplasm · primary systemic amyloidosis · refractory malignant neoplasm · T-cell acute lymphoblastic leukemia · testicular lymphoma · Wiskott-Aldrich syndrome · X-linked lymphoproliferative syndrome · acquired polycythemia vera · acute erythroid leukemia · acute graft versus host disease · acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) · aggressive B-cell non-Hodgkin lymphoma · ALK-negative anaplastic large cell lymphoma · CD4+/CD56+ hematodermic neoplasm · Chediak-Higashi syndrome · childhood botryoid rhabdomyosarcoma · childhood myelodysplastic syndrome · Diamond-Blackfan anemia · enteropathy-associated T-cell lymphoma · eosinophilic granulomatosis with polyangiitis · ependymoma · estrogen-receptor positive breast cancer · extranodal nasal NK/T cell lymphoma · fallopian tube carcinoma · glioblastoma · grade III lymphomatoid granulomatosis · granulomatosis with polyangiitis · hematopoietic and lymphoid system neoplasm · idiopathic membranous glomerulonephritis · IgA glomerulonephritis · intraocular lymphoma · kidney Wilms tumor · Langerhans cell histiocytosis · liver cancer · lymphoproliferative syndrome · male breast carcinoma · malignant pleural mesothelioma · metastatic prostate carcinoma · mixed phenotype acute leukemia · monoclonal gammopathy · nodular lymphocyte predominant Hodgkin lymphoma · pancreatic adenocarcinoma · peritoneum cancer · primary central nervous system lymphoma · primary cutaneous B-cell lymphoma · prostate adenocarcinoma · prostate cancer · pulmonary fibrosis · severe congenital neutropenia · Shwachman-Diamond syndrome · spindle cell rhabdomyosarcoma · T-cell non-Hodgkin lymphoma · T-cell prolymphocytic leukemia · therapy related acute myeloid leukemia and myelodysplastic syndrome · thrombocytopenia · acute myeloid leukemia with multilineage dysplasia · acute myeloid leukemia, FLT3 internal tandem duplication · acute myeloid leukemia, t(16;16)(p13.1;q22) · acute promyelocytic leukemia · acute undifferentiated leukemia · ALK-positive anaplastic large cell lymphoma · atypical chronic myeloid leukemia, BCR-ABL1 negative · B-cell childhood acute lymphoblastic leukemia · beta thalassemia · botryoid rhabdomyosarcoma · castration-resistant prostate carcinoma · central nervous system cancer · central nervous system non-hodgkin lymphoma · cervical cancer · childhood acute megakaryoblastic leukemia · childhood ependymoma · choroid plexus neoplasm · chronic graft versus host disease · Crohn disease · cutaneous neuroendocrine carcinoma · diffuse intrinsic pontine glioma · embryonal tumor with multilayered rosettes · engraftment syndrome · estrogen-receptor negative breast cancer · focal segmental glomerulosclerosis · ganglioneuroblastoma · gastric cancer · germ cell tumor · Glanzmann thrombasthenia · Griscelli syndrome · head and neck squamous cell carcinoma · hematologic disorder · high-grade B-cell lymphoma double-hit/triple-hit · Hodgkin's lymphoma, lymphocytic depletion · Hodgkin's lymphoma, mixed cellularity · immunoglobulin A vasculitis · impaired renal function disease · interstitial lung disease · kidney failure · lymphoid hemopathy · lymphoplasmacytic lymphoma · malignant mesothelioma · medulloblastoma non-WNT/non-SHH group 3 · medulloblastoma non-WNT/non-SHH group 4 · membranous glomerulonephritis · metastatic neoplasm · mycosis fungoides and variants · myelodysplastic syndrome associated with isolated del(5q) · myeloid leukemia · myxoid liposarcoma · neuroendocrine neoplasm · Nodal T-follicular helper cell lymphoma, follicular type · nodular sclerosis classical Hodgkin lymphoma · oral cavity squamous cell carcinoma · pediatric lymphoma · pineoblastoma · plasma cell leukemia · pleuropulmonary blastoma · polyarteritis nodosa · precursor B-cell acute lymphoblastic leukemia · precursor lymphoblastic lymphoma/leukemia · primary brain neoplasm · primary cutaneous T-cell non-Hodgkin lymphoma · primitive neuroectodermal tumor · progesterone-receptor negative breast cancer · progesterone-receptor positive breast cancer · relapsing-remitting multiple sclerosis · rheumatoid arthritis · scleroderma · severe combined immunodeficiency · small intestine cancer · small intestine lymphoma · squamous cell carcinoma · T-lymphoblastic lymphoma · acquired adult-onset immunodeficiency · acquired hemophagocytic lymphohistiocytosis associated with malignant disease · acquired lipodystrophy · acquired thrombocytopenia · acute myeloblastic leukemia with maturation · acute myeloblastic leukemia without maturation · acute myeloid leukemia, del(5q31-q32) · acute myeloid leukemia, inv(16)(p13.1;q22) · acute myeloid leukemia, inv(3)(q21.3;q26.2) · acute myeloid leukemia, t(6;9)(p23;q34.1) · acute myelomonocytic leukemia M4 · adenocarcinoma · adenocarcinoma in situ · adrenal cortex carcinoma · adult acute monocytic leukemia · Alzheimer disease · amyotrophic lateral sclerosis · anaplastic ependymoma · anemia · anti-neutrophil cytoplasmic antibody-associated vasculitis · antiphospholipid syndrome · antisynthetase syndrome · autoimmune hemolytic anemia · B-cell adult acute lymphocytic leukemia · B-cell lymphoma, unclassifiable, with features intermediate between diffuse large b-cell lymphoma and classical Hodgkin lymphoma · B-lymphoblastic leukemia/lymphoma with hypodiploidy · Behcet disease · benign neoplasm · bone osteosarcoma · breast adenocarcinoma · breast carcinoma in situ · carcinoid tumor · carcinoma of soft palate · cellular ependymoma · central nervous system germ cell tumor · central nervous system germinoma · central nervous system leukemia · chordoma · chronic progressive multiple sclerosis · chronic renal failure syndrome · clear cell ependymoma · clear cell sarcoma of kidney · colorectal adenocarcinoma · combined thymoma · congenital amegakaryocytic thrombocytopenia · conjunctival cancer · dedifferentiated chondrosarcoma · desmoplastic small round cell tumor · desmoplastic/nodular medulloblastoma · diarrheal disease · differentiated thyroid carcinoma · ductal breast carcinoma in situ and lobular carcinoma in situ · embryonal rhabdomyosarcoma · endometrial cancer · ependymoblastoma · esophageal cancer · essential thrombocythemia · Ewing sarcoma of bone · Ewing sarcoma/peripheral primitive neuroectodermal tumor · extramedullary plasmacytoma · extramedullary soft tissue plasmacytoma · extraocular retinoblastoma · extraskeletal Ewing sarcoma · fallopian tube clear cell adenocarcinoma · fallopian tube endometrioid adenocarcinoma · fallopian tube mucinous adenocarcinoma · fallopian tube serous adenocarcinoma · Felty syndrome · fibrolamellar hepatocellular carcinoma · follicular lymphoma, susceptibility to · gastric adenocarcinoma · gastric diffuse large B-cell lymphoma · gastric mucosa-associated lymphoid tissue lymphoma · gastroesophageal junction adenocarcinoma · GATA2 deficiency with susceptibility to MDS/AML · glioma · gliosarcoma · head and neck carcinoma · hemophagocytic syndrome · hepatoblastoma · histiocytic and dendritic cell neoplasm · histiocytosis · hormone-resistant prostate carcinoma · idiopathic aplastic anemia · idiopathic inflammatory myopathy · idiopathic multicentric Castleman disease · idiopathic pulmonary fibrosis · idiopathic scleritis · inborn error of immunity · inborn errors of metabolism · intraocular retinoblastoma · invasive ductal breast carcinoma · invasive lobular breast carcinoma · light chain deposition disease · luminal B breast carcinoma · lymphoblastic leukemia, acute, with lymphomatous features · lymphoid neoplasm · lymphomatoid granulomatosis · malignant epithelial tumor of ovary · malignant leptomeningeal tumor · mature T-cell and NK-cell non-Hodgkin lymphoma · mediastinal gray zone lymphoma · medulloblastoma SHH activated and TP53 wild-type · medulloblastoma with extensive nodularity · medulloepithelioma · melanoma tumor antigen Gp90 · meningeal tuberculosis · mesenchymal chondrosarcoma · metabolic disease · metastatic malignant neoplasm in the brain · mixed cell type kidney Wilms' tumor · multicentric Castleman disease · myalgic encephalomeyelitis/chronic fatigue syndrome · mycosis fungoides · myeloid hemopathy · myeloproliferative neoplasm, unclassifiable · myopathy · neoplasm of chest wall · neoplasm of mature B-cells · neoplasm of mediastinum · neoplasm of testis · nephrotic syndrome · neuroepithelioma · neuromyelitis optica · non-amyloid fibrillary glomerulopathy · ocular melanoma · olfactory neuroblastoma · opsoclonus-myoclonus syndrome · osteopetrosis · ovarian clear cell adenocarcinoma · ovarian endometrioid adenocarcinoma · ovarian mucinous adenocarcinoma · ovarian neoplasm · ovarian serous adenocarcinoma · pancreatic ductal adenocarcinoma · papillary ependymoma · paraneoplastic sensory ganglionopathy · pauci-immune glomerulonephritis with ANCA · pediatric meningioma · pemphigus · pemphigus vulgaris · peripheral primitive neuroectodermal tumor of bone · peripheral primitive neuroectodermal tumor of soft tissues · Philadelphia-positive myelogenous leukemia · POEMS syndrome · polyneuropathy, inflammatory demyelinating, chronic · primary acquired red cell aplasia · primary organ-specific lymphoma · primary peritoneal serous adenocarcinoma · prostate neoplasm · pseudomyxoma peritonei · pure red-cell aplasia · rapid-onset childhood obesity-hypothalamic dysfunction-hypoventilation-autonomic dysregulation syndrome · refractory precursor T-lymphoblastic lymphoma/leukemia · relapsed/refractory diffuse large B-cell lymphoma · rhabdoid tumor of the kidney · Richter transformation · serous adenocarcinoma · solitary osseous plasmacytoma · squamous cell lung carcinoma · subcutaneous panniculitis-like T-cell lymphoma · supratentorial primitive neuroectodermal tumor · T-cell adult acute lymphocytic leukemia · T-cell/histiocyte rich large B cell lymphoma · Takayasu arteritis · thrombocytopenic purpura · thymic carcinoma · thymic epithelial neoplasm · thymoma · thyroid gland carcinoma · transplant rejection · type 1 diabetes mellitus · undifferentiated carcinoma of nasopharynx · undifferentiated ovarian carcinoma · unilateral retinoblastoma · urinary bladder cancer · urothelial carcinoma · uveal melanoma · vasculitis · virus associated tumor · Wilms tumor · acquired hemophilia · acquired hemophilia A · anogenital human papillomavirus infection · autoimmune thrombocytopenic purpura · B-cell neoplasm · breast mucinous carcinoma · early T cell progenitor acute lymphoblastic leukemia · gestational trophoblastic neoplasm · hemopoietic proliferation · idiopathic nephrotic syndrome · invasive tubular breast carcinoma · mixed connective tissue disease · mucous membrane pemphigoid · oral cavity cancer · T-cell large granular lymphocyte leukemia · T-cell leukemia
Investigated by
National Cancer Institute (NCI) · M.D. Anderson Cancer Center · Children's Oncology Group · Memorial Sloan Kettering Cancer Center · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Fred Hutchinson Cancer Center
+857 more · SWOG Cancer Research Network · St. Jude Children's Research Hospital · Amgen · Hoffmann-La Roche · Masonic Cancer Center, University of Minnesota · National Heart, Lung, and Blood Institute (NHLBI) · City of Hope Medical Center · Dana-Farber Cancer Institute · Genentech, Inc. · Sanofi · Celgene Corporation · Mayo Clinic · ImmunityBio, Inc. · Alliance for Clinical Trials in Oncology · Eastern Cooperative Oncology Group · Merck Sharp & Dohme LLC · Fudan University · Institute of Hematology & Blood Diseases Hospital, China · European Organisation for Research and Treatment of Cancer - EORTC · Children's Cancer and Leukaemia Group · Northwestern University · Bristol-Myers Squibb · Case Comprehensive Cancer Center · UNICANCER · Millennium Pharmaceuticals, Inc. · Peking University People's Hospital · Sun Yat-sen University · The First Affiliated Hospital with Nanjing Medical University · University of Nebraska · H. Lee Moffitt Cancer Center and Research Institute · NSABP Foundation Inc · National Institute of Allergy and Infectious Diseases (NIAID) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · University of Washington · Asan Medical Center · Assistance Publique - Hôpitaux de Paris · Cancer and Leukemia Group B · German CLL Study Group · Medical Research Council · NYU Langone Health · Pfizer · University of Cologne · Baylor College of Medicine · Cancer Research UK · Johns Hopkins University · PETHEMA Foundation · Roche Pharma AG · Ruijin Hospital · University of Arkansas · Bayer · Emory University · Fondazione EMN Italy Onlus · Fondazione Italiana Linfomi - ETS · Genzyme, a Sanofi Company · GlaxoSmithKline · Guangdong Provincial People's Hospital · Lymphoma Study Association · Medical College of Wisconsin · Shanghai Jiao Tong University School of Medicine · Tianjin Medical University Cancer Institute and Hospital · Eli Lilly and Company · GBG Forschungs GmbH · Nanfang Hospital, Southern Medical University · National Marrow Donor Program · Samsung Medical Center · Scottish Cancer Therapy Network · University of Maryland, Baltimore · Blood and Marrow Transplant Clinical Trials Network · Brigham and Women's Hospital · Columbia University · Gustave Roussy, Cancer Campus, Grand Paris · Institut Curie · NCIC Clinical Trials Group · Novartis · all 863 on the full record

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansion US (FDA) CYTOXAN — 1987-04-29 fda.gov ↗
Approved US (FDA) CYTOXAN (LYOPHILIZED) — 1959-11-16 fda.gov ↗

Trials 1,719 · started per year

today
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 016 trials · 1 met primary
Phase 0 NCT06942039 Sep 2025 → Dec 2030 expected atypical teratoid rhabdoid tumor, childhood medulloblastoma, embryonal tumor with multilayered rosettes, ependymoblastoma +5 C17 Council Recruiting No outcome recorded
Phase 0 NCT06972069 May 2025 → Dec 2030 expected disease related to solid organ transplantation, kidney failure Tatsuo Kawai, MD, PhD Active not recruiting No outcome recorded
Phase 0 NCT06142396 Nov 2024 → Nov 2027 expected kidney failure, plasma cell myeloma Augusta University Recruiting No outcome recorded
Phase 0 NCT04947501 Jun 2021 → Jun 2026 overdue childhood malignant neoplasm, neuroblastoma Memorial Sloan Kettering Cancer Center Active not recruiting No outcome recorded
Phase 0 NCT03910452 Oct 2019 → Jun 2034 expected chronic granulomatous disease National Institute of Allergy and Infectious Diseases (NIAID) Active not recruiting No outcome recorded
Phase 0 NCT03719105 Mar 2019 → Dec 2027 expected aggressive NK-cell leukemia New York Medical College Recruiting No outcome recorded
Phase 0 NCT06361264 Nov 2018 → Dec 2024 female breast carcinoma KARANAHAN Unknown No outcome recorded
Phase 0 NCT03153410 Sep 2018 → Mar 2022 malignant pancreatic neoplasm Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Completed Met primary
Phase 0 NCT02212574 Apr 2017 → Nov 2018 medulloblastoma Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Terminated No outcome recorded
Phase 0 NCT02728271 Apr → Jul 2016 eosinophilic granulomatosis with polyangiitis Mounzer Agha Terminated No outcome recorded
Phase 1142 trials · 1 met primary · 1 missed
Phase 1 NCT04579523 Jun 2027 → Dec 2028 plasma cell myeloma Fred Hutchinson Cancer Center Withdrawn No outcome recorded Stop: Enrollment
Phase 1 NCT07672483 Oct 2026 → Jan 2028 expected cancer or benign tumor National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 1 NCT07341867 Aug 2026 → Mar 2028 expected plasma cell myeloma, triple-negative breast carcinoma Andrew Hantel, MD Not yet recruiting No outcome recorded
Phase 1 NCT06996119 Jun 2026 → May 2027 expected acute myeloid leukemia, graft versus host disease, myelodysplastic syndrome City of Hope Medical Center Recruiting No outcome recorded
Phase 1 NCT07194044 Feb 2026 → Oct 2030 expected Ewing sarcoma H. Lee Moffitt Cancer Center and Research Institute Recruiting No outcome recorded
Phase 1 NCT07278856 Dec 2025 → Mar 2027 expected Nodal T-follicular helper cell lymphoma, follicular type, angioimmunoblastic T-cell lymphoma, peripheral T-cell lymphoma, not otherwise specified City of Hope Medical Center Recruiting No outcome recorded
Phase 1 NCT07085104 Nov 2025 → Feb 2028 expected idiopathic inflammatory myopathy, systemic lupus erythematosus, systemic sclerosis Allogene Therapeutics Recruiting No outcome recorded
Phase 1 NCT07178171 Nov 2025 → Aug 2027 expected triple-negative breast carcinoma Xijing Hospital Recruiting No outcome recorded
Phase 1 NCT06959537 Aug 2025 → Jan 2027 breast cancer M.D. Anderson Cancer Center Suspended No outcome recorded
Phase 1 NCT05757310 Nov 2024 → Jun 2027 expected aplastic anemia City of Hope Medical Center Recruiting No outcome recorded
Show all 142 trials opens the full record — a long page
Phase 1/2143 trials · 1 met primary · 2 missed
Phase 1/2 NCT07675174 Jul 2026 → Jul 2030 expected graft versus host disease Northwell Health Not yet recruiting No outcome recorded
Phase 1/2 NCT07496229 Apr 2026 → Sep 2029 expected T-cell non-Hodgkin lymphoma Dizal Pharmaceuticals Recruiting No outcome recorded
Phase 1/2 NCT07061938 Jan 2026 → Sep 2029 expected immunoglobulin G4-related sclerosing disease Acepodia Biotech, Inc. Recruiting No outcome recorded
Phase 1/2 NCT06176027 Oct 2024 → Sep 2028 expected peripheral T-cell lymphoma, not otherwise specified Navy General Hospital, Beijing Recruiting No outcome recorded
Phase 1/2 NCT06681922 Sep 2024 → Oct 2027 expected graft versus host disease Northwell Health Recruiting No outcome recorded
Phase 1/2 NCT06145282 Dec 2023 → Oct 2025 overdue sickle cell disease National Heart, Lung, and Blood Institute (NHLBI) Active not recruiting No outcome recorded
Phase 1/2 NCT05895201 Nov 2023 → Dec 2025 acute myeloid leukemia, adult acute lymphoblastic leukemia, chronic myelomonocytic leukemia, disease related to hematopoietic stem cell transplant +1 Indiana University Withdrawn No outcome recorded
Phase 1/2 NCT06040320 Oct 2023 → May 2027 expected post-transplant lymphoproliferative disease Washington University School of Medicine Active not recruiting No outcome recorded
Phase 1/2 NCT05508009 Jan 2023 → Oct 2032 expected chronic kidney disease, cystinosis, focal segmental glomerulosclerosis, lupus nephritis Alice Bertaina Recruiting No outcome recorded
Phase 1/2 NCT05436418 Nov 2022 → Jun 2027 expected disease related to hematopoietic stem cell transplant National Cancer Institute (NCI) Recruiting No outcome recorded
Show all 143 trials opens the full record — a long page
Phase 2956 trials · 16 met primary · 23 missed
Phase 2 NCT07588698 Nov 2026 → Aug 2028 expected diffuse large B-cell lymphoma Carrie Ho, MD Not yet recruiting No outcome recorded
Phase 2 NCT07524530 Oct 2026 → Jun 2033 expected core binding factor acute myeloid leukemia, lymphoma National Cancer Institute (NCI) Not yet recruiting No outcome recorded
Phase 2 NCT07834450 Oct 2026 → Oct 2028 expected amyotrophic lateral sclerosis Huashan Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07856069 Oct 2026 → Oct 2030 expected medulloblastoma Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Not yet recruiting No outcome recorded
Phase 2 NCT07801898 Sep 2026 → Sep 2028 expected invasive breast carcinoma The Second Hospital of Anhui Medical University Not yet recruiting No outcome recorded
Phase 2 NCT07624799 Sep 2026 → Sep 2028 expected chronic lymphocytic leukemia/small lymphocytic lymphoma French Innovative Leukemia Organisation Not yet recruiting No outcome recorded
Phase 2 NCT07677306 Jul 2026 → Dec 2027 expected myelodysplastic syndrome Peking University People's Hospital Recruiting No outcome recorded
Phase 2 NCT07652879 Jun 2026 → Jan 2028 expected POEMS syndrome Shanghai Changzheng Hospital Recruiting No outcome recorded
Phase 2 NCT07643103 Jun 2026 → May 2028 expected precursor B-cell acute lymphoblastic leukemia Institute of Hematology & Blood Diseases Hospital, China Not yet recruiting No outcome recorded
Phase 2 NCT07608978 Jun 2026 → Dec 2028 expected diffuse large B-cell lymphoma The First Affiliated Hospital with Nanjing Medical University Recruiting No outcome recorded
Show all 956 trials opens the full record — a long page
Phase 2/341 trials · 3 met primary · 2 missed
Phase 2/3 NCT07463313 Mar 2026 → Mar 2029 expected combined thymoma Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Not yet recruiting No outcome recorded
Phase 2/3 NCT07297914 Jan 2026 → Nov 2032 expected acute graft versus host disease, acute lymphoblastic leukemia Bambino Gesù Hospital and Research Institute Not yet recruiting No outcome recorded
Phase 2/3 NCT07168980 Jul 2025 → Jun 2030 expected B-cell non-Hodgkin lymphoma Children's Cancer Group, China Recruiting No outcome recorded
Phase 2/3 NCT07059156 Jun 2025 → Jun 2027 expected adult acute lymphoblastic leukemia Shanxi Bethune Hospital Recruiting No outcome recorded
Phase 2/3 NCT06563245 Sep 2024 → Nov 2029 expected classic Hodgkin lymphoma Children's Cancer Group, China Recruiting No outcome recorded
Phase 2/3 NCT06475820 Dec 2023 → Jul 2024 overdue acute biphenotypic leukemia, myelodysplastic syndrome Federal Research Institute of Pediatric Hematology, Oncology and Immunology Active not recruiting No outcome recorded
Phase 2/3 NCT03759093 Sep 2023 → Sep 2025 plasma cell myeloma National University Hospital, Singapore Unknown No outcome recorded
Phase 2/3 NCT05462613 May 2023 → Nov 2029 expected colorectal cancer Centre Hospitalier Universitaire de Besancon Recruiting No outcome recorded
Phase 2/3 NCT06324266 Apr 2023 → Dec 2025 plasma cell myeloma Jinling Hospital, China Unknown No outcome recorded
Phase 2/3 NCT04753177 Jan 2021 → Jan 2023 — Saint Petersburg State Budgetary Healthcare Institution, City Clinical Oncology Dispensary Unknown No outcome recorded
Phase 3284 trials · 25 met primary · 51 missed
Phase 3 NCT07291102 Jul 2026 → Oct 2034 expected medulloblastoma SHH activated and TP53 wild-type Nationwide Children's Hospital Not yet recruiting No outcome recorded
Phase 3 NCT07466316 Jun 2026 → Mar 2031 expected rhabdomyosarcoma Children's Oncology Group Not yet recruiting No outcome recorded
Phase 3 NCT07193420 Jun 2026 → Jun 2030 expected graft versus host disease Assistance Publique - Hôpitaux de Paris Not yet recruiting No outcome recorded
Phase 3 NCT07239271 Nov 2025 → Dec 2027 expected HER2 positive breast carcinoma Cancer Institute and Hospital, Chinese Academy of Medical Sciences Not yet recruiting No outcome recorded
Phase 3 NCT07215585 Nov 2025 → Jun 2030 expected large B-cell lymphoma AstraZeneca Recruiting No outcome recorded
Phase 3 NCT06983821 Nov 2025 → Feb 2028 expected granulomatosis with polyangiitis, microscopic polyangiitis Ottawa Hospital Research Institute Recruiting No outcome recorded
Phase 3 NCT06401330 Apr 2025 → Feb 2031 expected mixed cell type kidney Wilms' tumor Children's Oncology Group Recruiting No outcome recorded
Phase 3 NCT06647953 Mar 2025 → Mar 2029 expected pleuropulmonary blastoma Children's Oncology Group Recruiting No outcome recorded
Phase 3 NCT06705062 Jan 2025 → Dec 2027 expected graft versus host disease Shanghai Jiao Tong University School of Medicine Recruiting No outcome recorded
Phase 3 NCT06781944 Oct 2024 → May 2028 expected idiopathic membranous glomerulonephritis Huashan Hospital Recruiting No outcome recorded
Show all 284 trials opens the full record — a long page
Phase 454 trials · 2 met primary · 2 missed
Phase 4 NCT05969522 Jan → Dec 2023 anti-neutrophil cytoplasmic antibody-associated vasculitis, pauci-immune glomerulonephritis with ANCA Wang Mo Unknown No outcome recorded
Phase 4 NCT06680349 Dec 2022 → Jan 2024 non-amyloid fibrillary glomerulopathy University of Turin, Italy Completed No outcome recorded
Phase 4 NCT05495893 Jul 2022 → May 2025 lupus nephritis Second Xiangya Hospital of Central South University Unknown No outcome recorded
Phase 4 NCT05420454 Jul 2022 → Jun 2027 expected breast cancer Second Affiliated Hospital, School of Medicine, Zhejiang University Recruiting No outcome recorded
Phase 4 NCT05420467 Jul 2022 → Jul 2027 expected breast cancer Second Affiliated Hospital, School of Medicine, Zhejiang University Recruiting No outcome recorded
Phase 4 NCT05207358 Mar 2022 → Dec 2028 expected lupus nephritis Institutul Clinic Fundeni Recruiting No outcome recorded
Phase 4 NCT04137640 Jul 2021 → Nov 2025 breast cancer Shengjing Hospital Unknown No outcome recorded
Phase 4 NCT04424602 Apr → Sep 2021 lupus nephritis Al-Azhar University Completed No outcome recorded
Phase 4 NCT04842318 Mar 2021 → Mar 2023 follicular lymphoma Ruijin Hospital Unknown No outcome recorded
Phase 4 NCT04762810 Jan 2020 → Feb 2023 — Peking Union Medical College Hospital Unknown No outcome recorded
Phase not applicable81 trials · 1 met primary · 2 missed
— NCT07495631 Apr 2026 → Mar 2028 expected adult acute lymphoblastic leukemia Institute of Hematology & Blood Diseases Hospital, China Recruiting No outcome recorded
— NCT07491822 Mar 2026 → Sep 2027 expected triple-negative breast carcinoma Tianjin Medical University Cancer Institute and Hospital Not yet recruiting No outcome recorded
— NCT06758726 Dec 2024 → Oct 2026 expected acute myeloid leukemia Institute of Hematology & Blood Diseases Hospital, China Not yet recruiting No outcome recorded
— NCT06490562 Jul 2024 → May 2028 expected acute graft versus host disease Institute of Hematology & Blood Diseases Hospital, China Not yet recruiting No outcome recorded
— NCT06451302 Apr 2024 → May 2027 expected Ewing sarcoma Yizhuo Zhang Active not recruiting No outcome recorded
— NCT06245707 Oct 2023 → Sep 2025 cognitive impairment with or without cerebellar ataxia, idiopathic membranous glomerulonephritis Beijing Friendship Hospital Unknown No outcome recorded
— NCT05876065 Jun 2023 → Jun 2026 overdue breast cancer Wenjin Yin Recruiting No outcome recorded
— NCT05936086 Apr 2023 → Apr 2026 overdue hemophagocytic syndrome shifeng Lou Recruiting No outcome recorded
— NCT05896813 Mar 2023 → Jan 2025 peripheral T-cell lymphoma, not otherwise specified The First Affiliated Hospital with Nanjing Medical University Unknown No outcome recorded
— NCT05777369 Mar → Aug 2023 diffuse large B-cell lymphoma The First Affiliated Hospital with Nanjing Medical University Unknown No outcome recorded
Phase not stated2 trials · 1 met primary
— NCT01005537 Jun 2009 → Oct 2010 cutaneous melanoma Fred Hutchinson Cancer Center No longer available No outcome recorded
— NCT00517894 — lymphoma Study Group of Medical Tumour Therapy (AGMT) No longer available Met primary
Comparator or background therapy2,731 trials
Phase 0 NCT07315503 Background Dec 2027 → Jan 2028 rheumatoid arthritis Institute of Hematology & Blood Diseases Hospital, China Withdrawn No outcome recorded Stop: Enrollment
Phase 0 NCT07535138 Background May 2026 → Jun 2028 expected IgA glomerulonephritis, lupus nephritis, membranous glomerulonephritis Air Force Military Medical University, China Not yet recruiting No outcome recorded
Phase 0 NCT07416682 Background Apr 2026 → Jan 2027 expected plasma cell neoplasm Affiliated Hospital to Academy of Military Medical Sciences Recruiting No outcome recorded
Phase 0 NCT07240857 Background Apr → Oct 2026 expected castration-resistant prostate carcinoma Zhejiang University Enrolling by invitation No outcome recorded
Phase 0 NCT06986434 Background Apr 2026 → May 2027 expected plasma cell neoplasm Affiliated Hospital to Academy of Military Medical Sciences Not yet recruiting No outcome recorded
Show all 2,731 trials opens the full record — a long page

Press releases naming this drug 8 releases

DateIssuerRelease
2025-08-01 Allogene Therapeutics Allogene Therapeutics Moves Forward with Standard Fludarabine and Cyclophosphamide (FC) Lymphodepletion Regimen in the ALPHA3 Trial for Cemacabtagene Ansegedleucel (Cema-Cel) in First-Line Consolidation for Large B-Cell Lymphoma allogene.com ↗
2024-02-28 Fresenius Kabi Fresenius Kabi Further Expands Oncology Portfolio with Launch of Cyclophosphamide for Injection, USP in the U.S. fresenius.com ↗
2024-02-28 Fresenius Kabi Fresenius Kabi Further Expands Oncology Portfolio with Launch of Cyclophosphamide for Injection, USP in the U.S. fresenius.com ↗
2023-12-14 Zydus Lifesciences Limited Zydus receives final approval from the USFDA for Cyclophosphamide Capsules USP, 25 mg and 50 mg zyduslife.com ↗
2020-03-31 Takeda Takeda Receives Positive CHMP Opinion for ADCETRIS ® (brentuximab vedotin) in Combination with CHP (Cyclophosphamide, Doxorubicin and Prednisone) for Treatment of Adult Patients with Previously Untreated Systemic Anaplastic Large Cell Lymphoma takeda.com ↗
2018-12-04 AbbVie IMBRUVICA® (ibrutinib) Combination Regimen Significantly Improved Survival Versus the Chemoimmunotherapy FCR (Fludarabine, Cyclophosphamide and Rituximab) in Previously Untreated and Younger Chronic Lymphocytic Leukemia (CLL) Patients; Late-Breaking Phase 3 Data at ASH 2018 abbvie.com ↗
2018-05-30 Impax Laboratories, LLC Amneal Announces FDA Approval of Cyclophosphamide for Injection USP, Generic to Cytoxan® amneal.com ↗
2017-09-07 Transgene Transgene and Institut Bergonié Present a Poster on the METROmaJX Trial (Oncolytic Virus Pexa-Vec + Metronomic Cyclophosphamide) at ESMO 2017 Congress transgene.com ↗

Evidence & citations 42 cited values

Every value below carries the sentence it was read from. 4,467 sources stand behind the page.

FieldValueCited text
Known as cyclophosphamide “Option 1: Docetaxel and carboplatin once every 3 weeks for 6 cycles; Option 2: Doxorubicin plus cyclophosphamide once every 3 weeks for 4 cycles, followed by a taxane...” NCT05415215 ↗
4404

“Standard Induction chemotherapy care included: vincristine, doxorubicin, and dexamethasone (VAD) (0.5 mg, 10 mg/m2, and 40 mg, respectively);dexamethasone,...” NCT00577096 ↗

“The study investigates the tolerance and the efficacy of a new combination of five drugs consisting of propranolol (antiangiogenetic, anti-neuroblastic), Celecoxib (modulating...” NCT02641314 ↗

“Patients initially received one 21-day cycle of standard rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP; rituximab 375 mg/m2, cyclophosphamide...” PMID 30948276 ↗ Apr 2019

“All enrolled patients will first complete a total of 6-8 cycles (21 days per cycle) of Standard R-CHOP chemotherapy (Rituximab + Cyclophosphamide + Doxorubicin + Prednisolone)...” NCT05874778 ↗

“One or more of the following may be assigned by the physician (physician's choice) per standard of care guidelines upon study enrollment following surgery: Cytarabine,...” NCT06861244 ↗

“RIC preconditioning regimen consisted of cytarabine (2 g/m2/day, days -10 to -9), busulfan (3.2 mg/kg/day on days -8 to -6), cyclophosphamide (1.0 g/m2/day, days -5 to -4),...” NCT03412266 ↗

“Consolidation 6-thioguanine 60 mg/m2/d, 1 to 43 po; prednisone 40 mg/m2/d, on days 1-28 orally; vincristine 1.5 mg/m2/d, days 1, 8, 15, 22; idarubicin 7 mg/m2/d, on days 1, 8,...” NCT06211452 ↗

“A Phase 3 Open Label Multicenter, Randomized Study to Compare the Efficacy and Safety of the Zevalin (Ibritumomab Tiuxetan) Therapeutic Regimen Following Cyclophosphamide,...” NCT00384111 ↗

“50% of the patients will receive Fludarabine + cyclophosphamide (F-araA 120 mg/m2 total dose for 3 days (d-3,-2,-1) over 1 h infusion and cyclophosphamide 25 mg/kg/d (d-5 to...” NCT03295058 ↗

“Recently, a less toxic regimen comprising reduced cyclophosphamide (Cy), fludarabine, and anti-thymocyte globulin (ATG) (Cy-Flu-ATG) was used to condition high-risk patients...” PMID 22526363 ↗ Apr 2012

Show 4,394 more sources

Known as B-518 “B-518” NCT03670966 ↗
Known as CFM “Cyclophosphamide (CFM): 1000 mg/m2, i.v., day 22.” NCT00526175 ↗
Known as Ciclofosfamide “Rituximab: 375 mg/mq day 1 Ciclofosfamide: 750 mg/mq day 1, Vincristina: 1,4 mg/mq day 1 Prednisone: 40 mg/mq day 1-5,” NCT00774826 ↗
2

NCT02365805 ↗

NCT00499018 ↗

Known as CPA “cyclophosphamide (CPA)” NCT01507103 ↗
1

“Cyclophosphamide (CPA)” NCT02049151 ↗

Known as CPH “Cyclophosphamide (CPH) therapeutic arm (CPH group) consisted of 8 boluses of intravenous cyclophosphamide (10mg/kg)” NCT00976300 ↗
Known as CPM “Nephritis is the most severe manifestation of lupus. Between 1950s and 1970s, corticosteroids were used for the treatment of lupus nephritis (LN) ,and using of...” NCT04424602 ↗
6

“Open-label studies suggested efficacy of monthly IV cyclophosphamide (CPM) without induction for delaying progression but no randomized trial was conducted so far.” PMID 28045953 ↗ Jan 2017

“104 weeks of continuous oral low dose chemotherapy with cyclophosphamide (CPM) and methotrexate (MTX)” NCT03063983 ↗

“additional cyclophosphamide (CPM) on day 10 only in T-ALL patients with prednisone poor-response” NCT01117441 ↗

“cyclophosphamide (CPM) on days 36 and 64” NCT00430118 ↗

“cyclophosphamide (CPM) on days 36 and 64” NCT00613457 ↗

“cyclophosphamide (CPM) IV over 1 hour” NCT00550992 ↗

Known as CTX “Iodine-131-labeled Monoclonal Antibody BC8 (anti-CD45), 131I-BC8; plus Busulfan, BU, NSC-750; Cyclophosphamide, CTX, NSC-26271; followed by Allogeneic Bone Marrow, ABM; with,...” NCT00002554 ↗
76

“The purpose of this study is to determine the safety of anti-HIV drugs combined with low-dose chemotherapy (consisting of cyclophosphamide [CTX]) in HIV-positive patients.” NCT00000899 ↗

“Participants with persistent proteinuria ≥ 1 g/day after 8 weeks of corticosteroid monotherapy will receive 0.8-1.0 g of intravenous cyclophosphamide (CTX) every 4 weeks” NCT03418779 ↗

“This study is a phase 1/2 study to assess safety and hematologic response rate of Ixazomib (MLN) in combination with Cyclophosphamide (CTX) and Dexamethasone (DEX).” NCT03236792 ↗

“Busulfan, BU, NSC-750; Cyclophosphamide, CTX, NSC-26271; followed by Allogeneic Bone Marrow, AlBM; with, as indicated, Intrathecal Cytarabine, IT ARA-C, NSC-63878.” NCT00002502 ↗

“prednisolone (PRED) (0.8mg/kg/d) plus Cyclophosphamide (CTX) (1.5-2mg/kg/d) followed by Azathioprine (AZA) (1-1.5mg/kg/d) as induction-maintenance therapy” NCT02954939 ↗

“cyclophosphamide(CTX) 600 mg/m2,i.v.,d1, sequential docetaxel 100 mg/m2,i.v.,d1, or paclitaxel(PTX) 80mg/m2,i.v.,d1,8,15, once every 21days, for 4 cycles.” NCT03949634 ↗

“an amendment to the trial added two cohorts, both received one dose of cyclophosphamide (CTX) administered 1 week before study treatment initiation” PMID 40187749 ↗ Apr 2025

“Oral administration of cyclophosphamide (CTX) and capecitabine may have a greater potential for treatment of metastatic breast cancer (MBC) due to” PMID 21874317 ↗ Aug 2011

“A single low dose of 200 mg/m2 of cyclophosphamide (CTX) will be administered intravenously up to 24 hours (Day 0) prior to each DNA vaccination.” NCT01493154 ↗

“Carboplatin, CBDCA, NSC-241240; or CAP: Cyclophosphamide, CTX, NSC-26271; Doxorubicin, DOX, NSC-123127; Cisplatin, CDDP, NSC-119875.” NCT00002477 ↗

Show 66 more sources

Known as CYC “In this comparative open-label cohort study, the investigators compared the efficacy and safety of tacrolimus (TAC)and cyclophosphamide (CYC) in the treatment of diffuse...” NCT01207297 ↗
12

“Scattered research in adults showed that both mycophenolate mofetil (MMF) and cyclophosphamide (CYC) can be used in the induction therapy of lupus nephritis.” NCT05495893 ↗

“Intravenous Cyclophosphamide (CYC), 600 mg/m² (adapted to age and renal function, maximal dose of 1.2 g) at Day 0, Day 15, M1, M2” NCT02460588 ↗

“PDN and oral cyclophosphamide (CYC) versus high dose intravenous (iv) CYC versus intermediate dose iv CYC” NCT00336414 ↗

“Mycophenolate might be an alternative therapy to avoid toxicities of cyclophosphamide (CYC).” PMID 26835147 ↗ Jan 2016

“including cyclophosphamide(CYC), methotrexate(MTX) and azathioprine(AZA) etc.” NCT03096275 ↗

“after lymphodepletion with fludarabine (flu) and cyclophosphamide (cyc).” PMID 31110096 ↗ May 2019

“oral azathioprine (AZA) versus intravenous pulse cyclophosphamide (CYC)” PMID 18240234 ↗ Feb 2008

“Lymphodepleting chemotherapy of cyclophosphamide (CYC) 300 mg/m2” NCT06152172 ↗

“limited cyclophosphamide (CYC) exposure” PMID 25693055 ↗ Apr 2015

“Chemotherapy: cyclophosphamide (CYC)” NCT06451159 ↗

Show 2 more sources

Known as cyclo “cyclophosphamide (cyclo; 50 mg per day, first 2 weeks in each 4 week cycle)” PMID 32620163 ↗ Jul 2020
Known as Cyclophosphamide (C) “Cyclophosphamide (C)” NCT01858922 ↗
Known as Cyclophosphamide (CPA) “Cyclophosphamide (CPA)” NCT00722098 ↗
1

“Cyclophosphamide - CPA” NCT00313235 ↗

Known as cyclophosphamide (CPM) “cyclophosphamide (CPM)” NCT01707004 ↗
Known as cyclophosphamide (CTX) “cyclophosphamide (CTX)” NCT01707004 ↗
Known as Cyclophosphamide - Cytoxan “Cyclophosphamide (Cytoxan ®)” NCT01860170 ↗
6

“Cyclophosphamide (Cytoxan®)” NCT02128230 ↗

“Cyclophosphamide - Cytoxan” NCT01001780 ↗

“Cyclophosphamide (Cytoxan)” NCT01527422 ↗

“cyclophosphamide (Cytoxan)” NCT00132691 ↗

“cyclophosphamide: cytoxan” NCT00640796 ↗

“cyclophosphamide,Cytoxan” NCT00085423 ↗

Known as Cyclophosphamide for Injection “Cyclophosphamide for Injection” NCT06939270 ↗
3

“Cyclophosphamide for Injection” NCT06481735 ↗

“Cyclophosphamide for Injection” NCT06838832 ↗

“Cyclophosphamide for Injection” NCT05554939 ↗

Known as Cyclophosphamide injection “Cyclophosphamide injection” NCT04714827 ↗
Known as cyclophosphamide sulfate “cyclophosphamide sulfate (CTX) IV over 1 hour on days 1-3 of weeks 6, 12, 18, and 24” NCT00002611 ↗
Known as Cyclophosphamide, Sendoxan, Baxter A/S “Cyclophosphamide, Sendoxan®, Baxter A/S” NCT00197912 ↗
2

“Cyclophosphamide, Sendoxan®, Baxter A/S” NCT00937625 ↗

“Cyclophosphamide, Sendoxan®, Baxter A/S” NCT00937300 ↗

Known as Cyclophosphamide: Endoxan “Cyclophosphamide: Endoxan” NCT01301040 ↗
Known as Cytophosphan ClinicalTrials.gov intervention name — accepted as the source's own label NCT01175772 ↗
Known as cytophosphane “Cyclophosphamide (CP), also known as cytophosphane among other names, is a chemotherapy agent” NCT04024761 ↗
Known as cytoxan “Patients will be randomized to receive 5 cycles of combination chemotherapy (5-FU, adriamycin, leucovorin, cytoxan, G-CSF) either as initial therapy (preoperative) or...” NCT00001250 ↗
58

“The patient will receive intravenous cyclophosphamide (200 mg/m2) or oral (cytoxan) before the vaccine, followed by DC vaccine and intravenous bevacizumab (15 mg/kg) the next day.” NCT03914768 ↗

“After the busulfan treatment, you will receive 4 doses each of two drugs, cyclophosphamide (also known as Cytoxan) and fludarabine, over 2 hours into your vein.” NCT00281879 ↗

“A Phase II Trial With VELCADE® (PS-341), Cytoxan (Cyclophosphamide), Dexamethasone and Thalomid® (VEL-CTD) in Previously Untreated Multiple Myeloma Patients” NCT00438841 ↗

“Combination chemotherapy consists of Flurouricil, Leucovorin, Adriamycin, and Cytoxan (FLAC) which will be given every 21 days for 10 cycles.” NCT00001239 ↗

“Cyclophosphamide (Cytoxan) 300 mg/m2 I.V., single dose, will be given to patients assigned to the SV-BR-1-GM.” NCT06072612 ↗

“Adriamycin (doxorubicin) and Cytoxan (cyclophosphamide) make up the chemotherapy regimen known as AC.” NCT00394251 ↗

“intravenous administration of doxorubicin (Adriamycin) followed by cyclophosphamide (Cytoxan)” NCT00256243 ↗

“FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF” NCT00001338 ↗

“a chemotherapy agent called cyclophosphamide (or Cytoxan) also at lower dose” NCT00595127 ↗

“Drug: Cyclophosphamide 750 mg/m2 i.v. for once (Day -5) Other Name: Cytoxan” NCT05211557 ↗

Show 48 more sources

Known as Cytoxan (Cyclophosphamide) “Cytoxan (Cyclophosphamide)” NCT00636441 ↗
Known as Cytoxan(R) (cyclophosphamide) “Cytoxan(R) (cyclophosphamide)” NCT00602667 ↗