drugset / Trial / NCT00199017
German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults
Non-randomizedSingle-groupOpen-labelTreatment
Summary
This study evaluates the efficacy and tolerability of treatment for T-lymphoblastic lymphoma (T-LBL) according to a protocol for acute lymphoblastic leukemia. Patients receive one year of intensive cyclical chemotherapy with additional prophylaxis for central nervous system (CNS) relapse by intrathecal therapy and cranial irradiation and mediastinal irradiation after induction chemotherapy.
Timeline
- Start
- 2004-04
- Primary completion
- 2009-03
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cladribine | Small molecule | — | — |
| Subject | Cyclophosphamide | Other / unclassified | — | — |
| Subject | Cytarabine | Small molecule | — | — |
| Subject | Daunorubicin | Small molecule | — | — |
| Subject | Dexamethasone | Small molecule | — | — |
| Subject | Doxorubicin | Other / unclassified | — | — |
| Subject | Etoposide | Small molecule | — | — |
| Subject | HDARAC | Unknown | — | — |
| Subject | MERCAPTOPURINE ANHYDROUS | Small molecule | — | — |
| Subject | Methotrexate | Small molecule | — | — |
| Subject | Prednisolone | Other / unclassified | — | — |
| Subject | Thioguanine | Small molecule | — | — |
| Subject | Vincristine | Small molecule | — | — |
| Subject | Vindesine | Small molecule | — | — |
| Subject | asparaginase | Protein / enzyme biologic | — | — |
| Background | G-CSF | Unknown | — | — |