Drugs / Etoposide
last change yesterday re-read 8 days ago

Etoposide

Small molecule targets HIF1A via activation

Developed for
lymphoma · small cell lung carcinoma · leukemia · neuroblastoma · Hodgkins lymphoma · plasma cell myeloma · ovarian cancer · diffuse large B-cell lymphoma
+322 more · lung cancer · non-Hodgkin lymphoma · central nervous system neoplasm · non-small cell lung carcinoma · sarcoma · myelodysplastic syndrome · acute lymphoblastic leukemia · acute myeloid leukemia · extragonadal germ cell tumor · extranodal nasal NK/T cell lymphoma · medulloblastoma · testicular germ cell tumor · breast cancer · Burkitt lymphoma · peripheral T-cell lymphoma, not otherwise specified · retinoblastoma · mantle cell lymphoma · classic Hodgkin lymphoma · hemophagocytic syndrome · lymphoblastic lymphoma · prostate cancer · acute myeloid leukemia with 11q23 abnormalities · anaplastic large cell lymphoma · childhood acute myeloid leukemia · childhood germ cell tumor · acute myeloid leukemia with t(8;21)(q22;q22) translocation · brain cancer · Ewing sarcoma · HIV infectious disease · B-cell non-Hodgkin lymphoma · cancer of unknown primary site · teratoma · acute myeloblastic leukemia with maturation · acute myeloblastic leukemia without maturation · acute myeloid leukemia with minimal differentiation · acute myeloid leukemia, t(16;16)(p13.1;q22) · acute myelomonocytic leukemia M4 · germ cell tumor · glioblastoma · hepatosplenic T-cell lymphoma · mature T-cell and NK-cell non-Hodgkin lymphoma · neuroendocrine carcinoma · primary mediastinal large B-cell lymphoma · soft tissue sarcoma · acute erythroid leukemia · acute megakaryoblastic leukemia in adult · adult acute monocytic leukemia · angioimmunoblastic T-cell lymphoma · atypical teratoid rhabdoid tumor · B-cell acute lymphoblastic leukemia · brain neoplasm · cancer · childhood malignant neoplasm · ependymoma · high grade B-cell lymphoma · kidney cancer · large B-cell lymphoma · large-cell immunoblastic lymphoma · osteosarcoma · plasma cell neoplasm · secondary hemophagocytic lymphohistiocytosis · acute myeloid leukemia, inv(16)(p13.1;q22) · adrenal cortex carcinoma · adult acute lymphoblastic leukemia · follicular lymphoma · high grade B-cell lymphoma with MYC and/ or BCL2 and/or BCL6 rearrangement · intraocular retinoblastoma · metastatic malignant neoplasm in the brain · myelodysplastic/myeloproliferative disease · ovarian carcinoma · supratentorial primitive neuroectodermal tumor · Waldenstrom macroglobulinemia · acquired hemophagocytic lymphohistiocytosis associated with malignant disease · acute leukemia · acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) · acute myeloid leukemia, del(5q31-q32) · acute promyelocytic leukemia · adult T-cell leukemia/lymphoma · aggressive B-cell non-Hodgkin lymphoma · ALK-negative anaplastic large cell lymphoma · B-cell lymphoma, unclassifiable, with features intermediate between diffuse large b-cell lymphoma and classical Hodgkin lymphoma · central nervous system cancer · central nervous system germ cell tumor · chronic lymphocytic leukemia/small lymphocytic lymphoma · cutaneous neuroendocrine carcinoma · enteropathy-associated T-cell lymphoma · fallopian tube cancer · head and neck cancer · hepatoblastoma · high-grade B-cell lymphoma double-hit/triple-hit · Kaposi's sarcoma · kidney Wilms tumor · myelodysplastic/myeloproliferative neoplasm · myeloproliferative neoplasm · neoplasm · primary brain neoplasm · primary peritoneal carcinoma · primitive neuroectodermal tumor · rhabdomyosarcoma · seminoma · T-cell acute lymphoblastic leukemia · T-cell non-Hodgkin lymphoma · triple-negative breast carcinoma · urinary bladder cancer · acute basophilic leukemia · ALK-positive anaplastic large cell lymphoma · anaplastic ependymoma · B-cell childhood acute lymphoblastic leukemia · B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) · central nervous system non-hodgkin lymphoma · childhood acute lymphoblastic leukemia · childhood medulloblastoma · childhood myelodysplastic syndrome · choriocarcinoma · digestive system neuroendocrine neoplasm · Ewing sarcoma of bone · female breast carcinoma · ganglioneuroblastoma · gastric cancer · gliosarcoma · grade III lymphomatoid granulomatosis · hematopoietic and lymphoid cell neoplasm · HER2 positive breast carcinoma · Hodgkin's lymphoma, lymphocytic depletion · Hodgkin's lymphoma, mixed cellularity · intraocular lymphoma · localized osteosarcoma · malignant epithelial tumor of ovary · malignant testicular germ cell tumor · MALT lymphoma · mixed germ cell tumor · nasal cavity and paranasal sinus neoplasm · neoplasm of testis · nodal marginal zone B-cell lymphoma · nodular lymphocyte predominant Hodgkin lymphoma · nodular sclerosis classical Hodgkin lymphoma · nongerminomatous germ cell tumor · pancreatic ductal adenocarcinoma · pineoblastoma · plasma cell leukemia · primary cutaneous T-cell non-Hodgkin lymphoma · primary systemic amyloidosis · pulmonary large cell neuroendocrine carcinoma · refractory malignant neoplasm · small cell carcinoma · small intestine cancer · splenic marginal zone lymphoma · subcutaneous panniculitis-like T-cell lymphoma · testicular cancer · testicular seminoma · therapy related acute myeloid leukemia and myelodysplastic syndrome · acute leukemia of ambiguous lineage · acute monocytic leukemia · acute myeloid leukemia and myelodysplastic syndromes related to alkylating agent · acute myeloid leukemia with multilineage dysplasia · acute myeloid leukemia with t(9;11)(p22;q23) · acute myeloid leukemia, t(8;21)(q22; q22.1) · aggressive NK-cell leukemia · alveolar rhabdomyosarcoma · anaplastic astrocytoma · anaplastic oligoastrocytoma · anaplastic oligodendroglioma · B-cell adult acute lymphocytic leukemia · benign neoplasm · blast phase chronic myelogenous leukemia, BCR-ABL1 positive · brain stem glioma · breast neoplasm · castration-resistant prostate carcinoma · cellular ependymoma · central nervous system germinoma · central nervous system nongerminomatous germ cell tumor · central nervous system vasculitis · cerebellar degeneration · cerebral primitive neuroectodermal tumor · cervical cancer · cervical carcinoma · childhood acute megakaryoblastic leukemia · childhood botryoid rhabdomyosarcoma · childhood central nervous system germinoma · childhood ependymoma · childhood kidney neoplasm · childhood testicular germ cell tumor · choroid plexus carcinoma · choroid plexus neoplasm · chronic inflammatory demyelinating polyradiculoneuropathy · clear cell ependymoma · clear cell sarcoma of kidney · combined thymoma · COVID-19 · desmoplastic/nodular medulloblastoma · diffuse intrinsic pontine glioma · diffuse midline glioma, H3 K27M-mutant · digestive system cancer · embryonal carcinoma · embryonal tumor with multilayered rosettes · ependymoblastoma · Epstein-Barr virus infection · erythroleukemia · esophageal small cell neuroendocrine carcinoma · Ewing sarcoma/peripheral primitive neuroectodermal tumor · extragonadal nonseminomatous germ cell tumor · extragonadal seminoma · extramedullary plasmacytoma · extraocular retinoblastoma · extraskeletal Ewing sarcoma · germinoma · hairy cell leukemia · hemopoietic proliferation · hepatocellular carcinoma · Her2-receptor negative breast cancer · high-grade neuroendocrine carcinoma of the cervix uteri · HIV-associated cancer · kidney neoplasm · Lambert-Eaton myasthenic syndrome · light chain deposition disease · liver cancer · lung adenocarcinoma · lung carcinoma · lung disorder · lung large cell carcinoma · lung neuroendocrine neoplasm · lymphoid hemopathy · lymphoid leukemia · lymphoid neoplasm · lymphomatoid granulomatosis · lymphoproliferative syndrome · malignant germ cell tumor · malignant pancreatic neoplasm · malignant tumor of meninges · mediastinal cancer · mediastinal gray zone lymphoma · medulloblastoma non-WNT/non-SHH group 3 · medulloblastoma non-WNT/non-SHH group 4 · medulloblastoma SHH activated and TP53 wild-type · medulloblastoma with extensive nodularity · medulloepithelioma · metastatic malignant neoplasm · mixed cell type kidney Wilms' tumor · mixed phenotype acute leukemia · multicentric Castleman disease · myasthenia gravis · mycosis fungoides and variants · myelodysplastic syndrome with excess blasts · myeloid leukemia · myeloid leukemia associated with down syndrome · myeloid sarcoma · nasopharyngeal carcinoma · neoplasm of mature B-cells · neoplasm of mediastinum · neoplasm of oropharynx · neuroendocrine neoplasm · neuroepithelioma · neuromyelitis optica · nut midline carcinoma · olfactory neuroblastoma · oligoastrocytoma · oligodendroglioma · opsoclonus-myoclonus syndrome · optic pathway glioma · ovarian embryonal carcinoma · ovarian germ cell tumor · ovarian granulosa cell tumor · ovarian gynandroblastoma · ovarian Sertoli-Leydig cell tumor · ovarian yolk sac tumor · papillary ependymoma · paranasal sinus cancer · pediatric ovarian germ cell tumor · pilocytic astrocytoma · pineal region germinoma · pineal region immature teratoma · pineal region yolk sac tumor · post-transplant lymphoproliferative disease · precursor lymphoblastic lymphoma/leukemia · primary central nervous system lymphoma · primary cutaneous B-cell lymphoma · primary cutaneous diffuse large B-cell lymphoma, Leg type · prostate adenocarcinoma · Rasmussen subacute encephalitis · refractory anemia with excess blasts in transformation · refractory hematologic cancer · refractory precursor T-lymphoblastic lymphoma/leukemia · relapsed/refractory diffuse large B-cell lymphoma · relapsing-remitting multiple sclerosis · rhabdoid tumor of the kidney · serous adenocarcinoma · small intestine lymphoma · soft tissue neoplasm · solitary osseous plasmacytoma · squamous cell carcinoma · squamous cell lung carcinoma · stiff-person syndrome · T-cell adult acute lymphocytic leukemia · T-cell childhood acute lymphocytic leukemia · T-cell large granular lymphocyte leukemia · T-cell/histiocyte rich large B cell lymphoma · T-lymphoblastic lymphoma · testicular embryonal carcinoma · testicular lymphoma · testicular non-seminomatous germ cell tumor · thymoma · undifferentiated high grade pleomorphic sarcoma of bone · unilateral retinoblastoma · urinary bladder small cell neuroendocrine carcinoma · urothelial carcinoma · Wilms tumor · yolk sac tumor · acute myeloid leukemia, FLT3 internal tandem duplication · colon adenocarcinoma · desmoplastic small round cell tumor · gastric neuroendocrine neoplasm · gestational trophoblastic neoplasm · hormone-resistant prostate carcinoma · intermittent vascular claudication · intestinal neuroendocrine neoplasm · malignant germ cell tumor of ovary · metastatic neoplasm · nasal cavity neoplasm · ovarian sex cord-stromal tumor · pancreatic neuroendocrine neoplasm · pancreatic neuroendocrine tumor · rectum adenocarcinoma
Investigated by
National Cancer Institute (NCI) · Children's Oncology Group · Memorial Sloan Kettering Cancer Center · M.D. Anderson Cancer Center · Alliance for Clinical Trials in Oncology · St. Jude Children's Research Hospital
+643 more · Children's Cancer and Leukaemia Group · SWOG Cancer Research Network · European Organisation for Research and Treatment of Cancer - EORTC · City of Hope Medical Center · Fudan University · AstraZeneca · Dana-Farber Cancer Institute · Eastern Cooperative Oncology Group · Samsung Medical Center · Genentech, Inc. · Gustave Roussy, Cancer Campus, Grand Paris · Medical Research Council · Fred Hutchinson Cancer Center · UNICANCER · Amgen · Beijing Friendship Hospital · Case Comprehensive Cancer Center · German Society for Pediatric Oncology and Hematology GPOH gGmbH · Sun Yat-sen University · University of Arkansas · University of Cologne · Cancer Research UK · Centre Leon Berard · Masonic Cancer Center, University of Minnesota · Qilu Hospital of Shandong University · Stanford University · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Tianjin Medical University Cancer Institute and Hospital · University of Nebraska · University of Washington · Asan Medical Center · Bristol-Myers Squibb · Cancer and Leukemia Group B · H. Lee Moffitt Cancer Center and Research Institute · Hoffmann-La Roche · NCIC Clinical Trials Group · Roswell Park Cancer Institute · University of Maryland, Baltimore · West China Second University Hospital · AIDS Malignancy Consortium · Baylor College of Medicine · Children's Cancer Group, China · Children's Hospital of Soochow University · Emory University · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · Fondazione Italiana Linfomi - ETS · Fox Chase Cancer Center · Fujian Cancer Hospital · Institut Curie · International Society of Pediatric Oncology · Lymphoma Study Association · Merck Sharp & Dohme LLC · National Institute of Allergy and Infectious Diseases (NIAID) · Radiation Therapy Oncology Group · Seoul National University Hospital · Shanghai Children's Medical Center · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Temple University · The First Affiliated Hospital with Nanjing Medical University · Washington University School of Medicine · Xiangya Hospital of Central South University · Assistance Publique - Hôpitaux de Paris · Barbara Ann Karmanos Cancer Institute · Chinese Academy of Medical Sciences · Columbia University · Duke University · European Infant Neuroblastoma Study Group - 1999 · Herbert Irving Comprehensive Cancer Center · Jiangsu HengRui Medicine Co., Ltd. · Lymphoma Trials Office · Mingzhi Zhang · Nanfang Hospital, Southern Medical University · Nanjing Children's Hospital · Nordic Lymphoma Group · all 649 on the full record

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansion US (FDA) VEPESID — 1986-09-04 fda.gov ↗
Approved US (FDA) VEPESID — 1983-11-10 fda.gov ↗

Trials 918 · started per year

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 06 trials
Phase 0 NCT06942039 Sep 2025 → Dec 2030 expected atypical teratoid rhabdoid tumor, childhood medulloblastoma, embryonal tumor with multilayered rosettes, ependymoblastoma +5 C17 Council Recruiting No outcome recorded
Phase 0 NCT04947501 Jun 2021 → Jun 2026 overdue childhood malignant neoplasm, neuroblastoma Memorial Sloan Kettering Cancer Center Active not recruiting No outcome recorded
Phase 0 NCT03719105 Mar 2019 → Dec 2027 expected aggressive NK-cell leukemia New York Medical College Recruiting No outcome recorded
Phase 0 NCT02905110 Oct 2017 → Mar 2022 brain cancer The University of Texas Health Science Center, Houston Completed No outcome recorded
Phase 0 NCT01760226 Jan 2013 → Aug 2016 post-transplant lymphoproliferative disease, primary mediastinal large B-cell lymphoma Baylor College of Medicine Completed No outcome recorded
Phase 0 NCT00662233 Oct 1991 → Oct 2013 ovarian cancer, sarcoma Mayo Clinic Completed No outcome recorded
Phase 164 trials
Phase 1 NCT05403723 Jan 2027 → Feb 2028 small cell lung carcinoma University of Maryland, Baltimore Suspended No outcome recorded
Phase 1 NCT07194044 Feb 2026 → Oct 2030 expected Ewing sarcoma H. Lee Moffitt Cancer Center and Research Institute Recruiting No outcome recorded
Phase 1 NCT06164327 Dec 2023 → Oct 2025 relapsed/refractory diffuse large B-cell lymphoma BeBetter Med Inc Unknown No outcome recorded
Phase 1 NCT05762419 Jun 2023 → Dec 2026 expected diffuse midline glioma, H3 K27M-mutant Columbia University Recruiting No outcome recorded
Phase 1 NCT05361395 Aug 2022 → May 2030 expected small cell lung carcinoma Amgen Active not recruiting No outcome recorded
Phase 1 NCT05546060 Jul 2022 → Jul 2025 hemophagocytic syndrome Beijing Friendship Hospital Unknown No outcome recorded
Phase 1 NCT05338541 May 2022 → Jun 2024 neuroblastoma Yizhuo Zhang Unknown No outcome recorded
Phase 1 NCT05106296 Feb 2022 → Mar 2028 expected ependymoma, glioblastoma, medulloblastoma, primary brain neoplasm Theodore S. Johnson Recruiting No outcome recorded
Phase 1 NCT05001412 Jan 2021 → Jan 2023 small cell lung carcinoma Zhou Chengzhi Unknown No outcome recorded
Phase 1 NCT04521946 Jan 2021 → Dec 2022 anaplastic ependymoma, atypical teratoid rhabdoid tumor, central nervous system germ cell tumor, choroid plexus carcinoma +3 M.D. Anderson Cancer Center Withdrawn No outcome recorded Stop: Enrollment
Phase 1/251 trials · 3 missed
Phase 1/2 NCT07850973 Mar 2027 → Dec 2029 expected malignant germ cell tumor M.D. Anderson Cancer Center Not yet recruiting No outcome recorded
Phase 1/2 NCT07843940 Oct 2026 → Apr 2030 expected small cell lung carcinoma Boehringer Ingelheim Not yet recruiting No outcome recorded
Phase 1/2 NCT07525466 Apr 2026 → Mar 2028 expected extranodal nasal NK/T cell lymphoma, secondary hemophagocytic lymphohistiocytosis Beijing Tongren Hospital Recruiting No outcome recorded
Phase 1/2 NCT07472647 Feb 2026 → Feb 2029 expected non-small cell lung carcinoma, small cell lung carcinoma Shanghai JMT-Bio Inc. Not yet recruiting No outcome recorded
Phase 1/2 NCT06485908 Oct 2024 → Apr 2026 overdue ependymoma, medulloblastoma Assistance Publique Hopitaux De Marseille Not yet recruiting No outcome recorded
Phase 1/2 NCT06477523 May 2024 → Dec 2026 expected small cell lung carcinoma Sichuan University Active not recruiting No outcome recorded
Phase 1/2 NCT06110572 Apr 2024 → Jun 2027 expected small cell lung carcinoma Vanderbilt-Ingram Cancer Center Recruiting No outcome recorded
Phase 1/2 NCT05882630 Jun 2023 → Jun 2025 small cell lung carcinoma Fujian Cancer Hospital Unknown No outcome recorded
Phase 1/2 NCT05664971 Feb 2023 → Oct 2025 lung cancer Shanghai Junshi Bioscience Co., Ltd. Completed No outcome recorded
Phase 1/2 NCT05590572 Jan 2023 → Dec 2026 expected osteosarcoma Second Affiliated Hospital, School of Medicine, Zhejiang University Not yet recruiting No outcome recorded
Phase 2527 trials · 8 met primary · 19 missed
Phase 2 NCT07699237 Nov 2026 → Jun 2031 expected small cell lung carcinoma University of Cologne Not yet recruiting No outcome recorded
Phase 2 NCT07258147 Oct 2026 → Dec 2027 expected small cell lung carcinoma Sichuan University Not yet recruiting No outcome recorded
Phase 2 NCT07856069 Oct 2026 → Oct 2030 expected medulloblastoma Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Not yet recruiting No outcome recorded
Phase 2 NCT07583550 Jul 2026 → Oct 2027 expected lung disorder Jiangmen Central Hospital Recruiting No outcome recorded
Phase 2 NCT06738368 May 2026 → Jan 2028 B-cell acute lymphoblastic leukemia, T-cell acute lymphoblastic leukemia University of Washington Suspended No outcome recorded
Phase 2 NCT07001995 May 2026 → Dec 2027 expected non-small cell lung carcinoma, small cell lung carcinoma Hunan Province Tumor Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07538271 Apr 2026 → Sep 2027 expected small cell lung carcinoma Yayi He Not yet recruiting No outcome recorded
Phase 2 NCT07538258 Apr 2026 → Sep 2027 expected small cell lung carcinoma Yayi He Not yet recruiting No outcome recorded
Phase 2 NCT07227584 Apr 2026 → Jul 2030 expected acute lymphoblastic leukemia Dana-Farber Cancer Institute Not yet recruiting No outcome recorded
Phase 2 NCT07361133 Apr → Aug 2026 overdue head and neck cancer, squamous cell carcinoma National Cancer Institute, Egypt Not yet recruiting No outcome recorded
Show all 527 trials opens the full record — a long page
Phase 2/320 trials
Phase 2/3 NCT01064466 Jul 2025 → Nov 2026 expected small cell lung carcinoma Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair Active not recruiting No outcome recorded
Phase 2/3 NCT07168980 Jul 2025 → Jun 2030 expected B-cell non-Hodgkin lymphoma Children's Cancer Group, China Recruiting No outcome recorded
Phase 2/3 NCT06563245 Sep 2024 → Nov 2029 expected classic Hodgkin lymphoma Children's Cancer Group, China Recruiting No outcome recorded
Phase 2/3 NCT04681417 Mar 2021 → Jan 2035 expected retinoblastoma Institut Curie Recruiting No outcome recorded
Phase 2/3 NCT04055038 Sep 2019 → Sep 2021 BRCA1-related cancer predisposition, BRCA2-related cancer predisposition, ovarian cancer, serous adenocarcinoma Blokhin's Russian Cancer Research Center Unknown No outcome recorded
Phase 2/3 NCT03733327 Nov 2018 → Oct 2021 disease related to hematopoietic stem cell transplant, primary central nervous system lymphoma Nanfang Hospital, Southern Medical University Unknown No outcome recorded
Phase 2/3 NCT03385096 Jan 2018 → Dec 2020 disease related to hematopoietic stem cell transplant, plasma cell myeloma Nanfang Hospital, Southern Medical University Unknown No outcome recorded
Phase 2/3 NCT03229616 Jul 2017 → Jun 2020 diffuse large B-cell lymphoma, disease related to hematopoietic stem cell transplant Nanfang Hospital, Southern Medical University Unknown No outcome recorded
Phase 2/3 NCT02265770 Jun 2015 → Jun 2028 expected childhood ependymoma Centre Leon Berard Recruiting No outcome recorded
Phase 2/3 NCT02405676 Jan 2015 → Dec 2023 overdue B-cell non-Hodgkin lymphoma Children's Cancer Group, China Active not recruiting No outcome recorded
Phase 3182 trials · 12 met primary · 27 missed
Phase 3 NCT07291102 Jul 2026 → Oct 2034 expected medulloblastoma SHH activated and TP53 wild-type Nationwide Children's Hospital Not yet recruiting No outcome recorded
Phase 3 NCT07497438 Apr 2026 → Dec 2029 expected secondary hemophagocytic lymphohistiocytosis Assistance Publique - Hôpitaux de Paris Not yet recruiting No outcome recorded
Phase 3 NCT07232134 Jul 2025 → Jul 2030 expected Down syndrome, acute myeloid leukemia Federal Research Institute of Pediatric Hematology, Oncology and Immunology Recruiting No outcome recorded
Phase 3 NCT06953739 May 2025 → Dec 2027 expected mature T-cell and NK-cell non-Hodgkin lymphoma The First Affiliated Hospital with Nanjing Medical University Not yet recruiting No outcome recorded
Phase 3 NCT06401330 Apr 2025 → Feb 2031 expected mixed cell type kidney Wilms' tumor Children's Oncology Group Recruiting No outcome recorded
Phase 3 NCT06520163 Aug 2024 → Aug 2026 overdue non-Hodgkin lymphoma The Affiliated People's Hospital of Ningbo University Recruiting No outcome recorded
Phase 3 NCT06520176 Aug 2024 → Dec 2026 expected hemopoietic proliferation, plasma cell myeloma The Affiliated People's Hospital of Ningbo University Recruiting No outcome recorded
Phase 3 NCT02633514 Dec 2023 → Dec 2024 combined thymoma Fudan University Withdrawn No outcome recorded Stop: Enrollment
Phase 3 NCT05711628 Aug 2023 → Jun 2028 classic Hodgkin lymphoma National Cancer Institute (NCI) Withdrawn No outcome recorded
Phase 3 NCT05496166 Aug 2023 → Aug 2027 expected small cell lung carcinoma Shanghai Pulmonary Hospital, Shanghai, China Not yet recruiting No outcome recorded
Show all 182 trials opens the full record — a long page
Phase 419 trials · 1 met primary
Phase 4 NCT06504030 Aug 2024 → Aug 2026 overdue hemophagocytic syndrome The First Affiliated Hospital of Soochow University Not yet recruiting No outcome recorded
Phase 4 NCT05491304 Sep 2022 → Dec 2024 cytokine release syndrome, hemophagocytic syndrome The Children's Hospital of Zhejiang University School of Medicine Unknown No outcome recorded
Phase 4 NCT04999878 May 2021 → Jun 2023 hemophagocytic syndrome, mature T-cell and NK-cell non-Hodgkin lymphoma Zhengzhou University Unknown No outcome recorded
Phase 4 NCT04038411 Apr 2019 → Apr 2021 mature T-cell and NK-cell non-Hodgkin lymphoma Mingzhi Zhang Unknown No outcome recorded
Phase 4 NCT03707847 Oct 2018 → Feb 2020 ALK-positive anaplastic large cell lymphoma Mingzhi Zhang Unknown No outcome recorded
Phase 4 NCT03500133 Oct 2017 → Oct 2027 expected Hodgkins lymphoma Hospital JP Garrahan Recruiting No outcome recorded
Phase 4 NCT03071822 Feb 2017 → Jul 2021 T-cell non-Hodgkin lymphoma The University of Hong Kong Unknown No outcome recorded
Phase 4 NCT04490590 Oct 2016 → Oct 2020 mature T-cell and NK-cell non-Hodgkin lymphoma Mingzhi Zhang Unknown No outcome recorded
Phase 4 NCT02858804 Jan 2016 → Dec 2019 mantle cell lymphoma Institute of Hematology & Blood Diseases Hospital, China Completed No outcome recorded
Phase 4 NCT02875314 Sep 2015 → Dec 2030 expected central nervous system cancer, medulloblastoma Parth Patel Active not recruiting No outcome recorded
Phase not applicable48 trials · 1 met primary · 2 missed
— NCT07389356 Feb 2026 → Oct 2027 expected diffuse large B-cell lymphoma The First Affiliated Hospital with Nanjing Medical University Not yet recruiting No outcome recorded
— NCT06462105 Jul 2024 → Jun 2027 expected small cell lung carcinoma Zhou Chengzhi Not yet recruiting No outcome recorded
— NCT06451302 Apr 2024 → May 2027 expected Ewing sarcoma Yizhuo Zhang Active not recruiting No outcome recorded
— NCT06069830 Dec 2023 → Oct 2026 expected extranodal nasal NK/T cell lymphoma Ruijin Hospital Recruiting No outcome recorded
— NCT05775705 Aug 2023 → Jul 2026 Epstein-Barr virus infection, acquired hemophagocytic lymphohistiocytosis associated with malignant disease, lymphoma Beijing Friendship Hospital Completed No outcome recorded
— NCT05705687 May 2023 → Feb 2031 expected nongerminomatous germ cell tumor Gustave Roussy, Cancer Campus, Grand Paris Recruiting No outcome recorded
— NCT05784987 Apr 2023 → Jan 2024 diffuse large B-cell lymphoma The First Affiliated Hospital with Nanjing Medical University Unknown No outcome recorded
— NCT05681403 Jan 2023 → Dec 2026 expected lymphoma First Affiliated Hospital Xi'an Jiaotong University Not yet recruiting No outcome recorded
— NCT05832320 Jan 2023 → Dec 2024 acute promyelocytic leukemia Peking University People's Hospital Unknown No outcome recorded
— NCT06946407 Dec 2022 → Dec 2027 expected central nervous system non-hodgkin lymphoma FengYan Jin Recruiting No outcome recorded
Phase not stated1 trial · 1 met primary
— NCT00517894 — lymphoma Study Group of Medical Tumour Therapy (AGMT) No longer available Met primary
Comparator or background therapy843 trials
Phase 0 NCT07059975 Background Oct 2025 → Oct 2028 expected childhood acute myeloid leukemia Joanna Yi Recruiting No outcome recorded
Phase 0 NCT04139304 Background May 2021 → Jul 2029 expected plasmablastic lymphoma AIDS Malignancy Consortium Recruiting No outcome recorded
Phase 0 NCT03568994 Background Jul 2018 → Sep 2020 acute myeloid leukemia Baylor College of Medicine Completed No outcome recorded
Phase 0 NCT02653196 Background Sep 2015 → Aug 2017 neuroepithelial neoplasm Montefiore Medical Center Terminated No outcome recorded
Phase 0 NCT01959477 Background Mar 2014 → Jan 2015 Burkitt lymphoma, Hodgkins lymphoma, MALT lymphoma, T-cell large granular lymphocyte leukemia +19 Case Comprehensive Cancer Center Completed No outcome recorded
Show all 843 trials opens the full record — a long page

Evidence & citations 31 cited values

Every value below carries the sentence it was read from. 1,766 sources stand behind the page.

FieldValueCited text
Known as etoposide “including but not limited to DHAP (dexamethasone, cisplatin, high-dose cytarabine), ESHAP (etoposide, methylprednisolone, high-dose cytarabine and cisplatin), DICE...” NCT04486391 ↗
1687

“Platinum (cisplatin or carboplatin)+VP-16: Cisplatin for injection 80-100mg/m2, divided into 3 days, the dose depends on tolerability, every 4 weeks as one cycle; carboplatin...” NCT07138001 ↗

“Standard Induction chemotherapy care included: vincristine, doxorubicin, and dexamethasone (VAD) (0.5 mg, 10 mg/m2, and 40 mg, respectively);dexamethasone,...” NCT00577096 ↗

“Control chemotherapy treatment will be chosen from any of the following standard-of-care chemotherapy drugs or combinations: * Carboplatin; * Irinotecan; * Etoposide; *...” NCT03632135 ↗

“The study investigates the tolerance and the efficacy of a new combination of five drugs consisting of propranolol (antiangiogenetic, anti-neuroblastic), Celecoxib (modulating...” NCT02641314 ↗

“standard EAP mobilization chemotherapy (etoposide 75 mg/m² i.v. d1-2, cytarabine 200 mg/m² q12h i.v. d1-2; pegfilgrastim is administered subcutaneously on day 6 after...” NCT07848672 ↗

“Drugs:Chidamide and ICE regimen (ifosfamide, Mesna,Carboplatin and etoposide): Chidamide 20mg on d1,4,8,11;ifosfamide 1.2g/ m2,d1-4,ivg during 4 hours; Mesna 0.4g, 0,4,8 hours...” NCT02856997 ↗

“The purpose of this study is to find out what the response is and the side effects are with chemotherapy using a combination of drugs called D.T. PACE (Dexamethasone,...” NCT00107614 ↗

“Acceptable histology-specific PDC regimens include carboplatin plus paclitaxel or nab-paclitaxel (any histology), carboplatin/cisplatin plus pemetrexed (nonsquamous),...” NCT06865339 ↗

“bleomycin 10 units/m\^2 IV on Day 8 etoposide 200 mg/m\^2 IV on Days 1, 2 and 3 doxorubicin 35 mg/m\^2 IV on Day 1 cyclophosphamide 1250 mg/m\^2 IV on Day 1 vincristine 1.4...” NCT01118026 ↗

“All patients will receive 8 cycles of R-CHOEP immunochemotherapy every two weeks with the following doses per cycle: rituximab 375 mg/m², cyclophosphamide 750 mg/m²,...” NCT03399513 ↗

Show 1,677 more sources

Known as Ad2/HIF-1α/VP16 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00117650 ↗
Known as EPI “EPI:etoposide” NCT03201471 ↗
Known as Eto “gemcitabine (Gem) with vinorelbine (Vin), etoposide (Eto), cisplatin (Cis), or carboplatin (Car).” PMID 22031232 ↗ Jan 2012
Known as Etopophos “Etoposide phosphate (Etopophos; Bristol-Myers Squibb Company, Princeton, NJ) is a water-soluble prodrug of etoposide” NCT06356883 ↗
Known as Etoposid ClinicalTrials.gov intervention name — accepted as the source's own label NCT07699237 ↗
Known as Etoposide (E) “Etoposide (E)” NCT01858922 ↗
Known as Etoposide (VdPesid) “Etoposide (VdPesid)” NCT00856830 ↗
Known as Etoposide (VP-16) (Vepesid) “Etoposide (VP-16) (Vepesid®)” NCT02128230 ↗
Known as Etoposide (VP-16; Vepesid(R) brand only) “Etoposide (VP-16; Vepesid(R) brand only)” NCT00005797 ↗
Known as Etoposide - VP-16, Etopophos, Toposar, VePesid “Etoposide - VP-16, Etopophos, Toposar, VePesid” NCT00613223 ↗
Known as Etoposide 20 mg/ml Concentrate for solution for infusion “Etoposide 20 mg/ml Concentrate for solution for infusion” NCT06418087 ↗
Known as Etoposide Capsule “Etoposide Capsule” NCT03707847 ↗
Known as Etoposide Capsules “Etoposide Capsules is given orally at a dosage of 50mg or 25mg daily, day 1 to 14 of a 21-day cycle” NCT07141264 ↗
1

“Apatinib Combined With Temozolomide and Etoposide Capsules” NCT04501718 ↗

Known as Etoposide injection “etoposide injection interferes with the division process of cancer cells to inhibit their growth and spread” NCT06897579 ↗
2

“Etoposide injection (E): 100mg/m2, ivgtt, d1,d2,d3,Q3W” NCT06614621 ↗

“Drug: Etoposide Injection” NCT06786312 ↗

Known as etoposide phosphate “Patients receive etoposide phosphate IV continuously on days 1-4, high-dose cytarabine IV over 2 hours every 12 hours for a total of 8 doses on days 1-4” NCT01256398 ↗
42

“Patients receive N5 chemotherapy comprising cisplatin IV continuously over 96 hours and etoposide phosphate IV continuously over 96 hours on days 1-4” NCT00410631 ↗

“etoposide phosphate IV over 2 hours” NCT00417053 ↗

“etoposide phosphate (etoposide)” NCT03113500 ↗

NCT00074165 ↗

NCT04663347 ↗

NCT02130869 ↗

NCT03440567 ↗

NCT06188676 ↗

NCT00689845 ↗

NCT01160731 ↗

Show 32 more sources

Known as Etoposide-Etopophos-Toposar-VePesid-VP-16 “Etoposide-Etopophos-Toposar-VePesid-VP-16” NCT00612430 ↗
Known as Etoposide: Eposin, Neoposid, Vepesid, Etopophos “Etoposide: Eposin, Neoposid, Vepesid, Etopophos” NCT01563601 ↗
Known as Etoposide: VP-16, VePesid, VP-16-213, EPEG, epipodophyllotoxin, NSC #141540 “Etoposide: VP-16, VePesid, VP-16-213, EPEG, epipodophyllotoxin, NSC #141540” NCT00958022 ↗
Known as NSC-141540 “CVP: Cyclophosphamide, CTX, NSC-26271; Etoposide, VP-16, NSC-141540; Cisplatin, CDDP, NSC-119875.” NCT00002488 ↗
8

“Etoposide, VP-16, NSC-141540.” NCT00002588 ↗

“Etoposide, VP-16, NSC-141540” NCT00002567 ↗

“Etoposide, VP-16, NSC-141540” NCT00002510 ↗

“Etoposide, VP-16, NSC-141540” NCT00002471 ↗

“VP-16 Etoposide, NSC-141540” NCT00002691 ↗

“VP-16 Etoposide, NSC-141540” NCT00001339 ↗

“VP-16 Etoposide, NSC-141540” NCT00002565 ↗

“VP-16 Etoposide, NSC-141540” NCT00002557 ↗

Known as NSC-301739 “NSC-301739 VP-16 Etoposide” NCT00002688 ↗
Known as VePesid “Etoposide (VePesid)” NCT00514540 ↗
Known as vepesid (etoposide) “vepesid (etoposide)” NCT01756989 ↗
Known as Vepesid(R), VP-16 (etoposide) “Vepesid(R), VP-16 (etoposide)” NCT00602667 ↗
Known as Vepeside ClinicalTrials.gov intervention name — accepted as the source's own label NCT02104986 ↗