Etoposide
Small molecule targets HIF1A via activation
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | VEPESID | — | 1986-09-04 | fda.gov ↗ |
| Approved | US (FDA) | VEPESID | — | 1983-11-10 | fda.gov ↗ |
Trials 916 · started per year
Also used as a comparator or background therapy in 836 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 07 trials | ||||||
| Phase 0 | NCT07059975 Background | Oct 2025 → Oct 2028 expected | childhood acute myeloid leukemia | Joanna Yi | Recruiting | No outcome recorded |
| Phase 0 | NCT04139304 Background | May 2021 → Jul 2029 expected | plasmablastic lymphoma | AIDS Malignancy Consortium | Recruiting | No outcome recorded |
| Phase 0 | NCT03568994 Background | Jul 2018 → Sep 2020 | acute myeloid leukemia | Baylor College of Medicine | Completed | No outcome recorded |
| Phase 0 | NCT02653196 Background | Sep 2015 → Aug 2017 | neuroepithelial neoplasm | Montefiore Medical Center | Terminated | No outcome recorded |
| Phase 0 | NCT01959477 Background | Mar 2014 → Jan 2015 | Burkitt lymphoma, Hodgkins lymphoma, MALT lymphoma, T-cell large granular lymphocyte leukemia +19 | Case Comprehensive Cancer Center | Completed | No outcome recorded |
| Phase 0 | NCT01331590 Background | Jul 2011 → Oct 2014 | precursor lymphoblastic lymphoma/leukemia | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 0 | NCT00515138 Background | May 2007 → Nov 2011 | B-cell non-Hodgkin lymphoma | University of California, San Francisco | Terminated | No outcome recorded |
| Phase 1144 trials | ||||||
| Phase 1 | NCT07688252 Background | Jul 2026 → Dec 2032 expected | neuroblastoma | Chang Gung Memorial Hospital | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT07381829 Background | Oct 2025 → Dec 2026 expected | — | HC Biopharma Inc. | Recruiting | No outcome recorded |
| Phase 1 | NCT07009457 Background | Jun 2025 → Sep 2027 expected | small cell lung carcinoma | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Active not recruiting | No outcome recorded |
| Phase 1 | NCT06719973 Background | May 2025 | cancer | EMD Serono Research & Development Institute, Inc. | Withdrawn | No outcome recorded |
| Phase 1 | NCT06732258 Background | Jan 2025 → Feb 2026 | small cell lung carcinoma | Sichuan University | Withdrawn | No outcome recorded |
| Show all 144 trials opens the full record — a long page | ||||||
| Phase 1/2114 trials | ||||||
| Phase 1/2 | NCT07227597 Comparator | Jan 2026 → Nov 2030 expected | small cell lung carcinoma | Merck Sharp & Dohme LLC | Recruiting | No outcome recorded |
| Phase 1/2 | NCT07141771 Background | Dec 2025 → Jun 2030 expected | small cell lung carcinoma | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Not yet recruiting | No outcome recorded |
| Phase 1/2 | NCT06937866 Background | Nov 2025 → Mar 2030 expected | germ cell tumor | Indiana University | Recruiting | No outcome recorded |
| Phase 1/2 | NCT06771622 Background | Mar 2025 → Jan 2028 expected | — | FBD Biologics Limited | Active not recruiting | No outcome recorded |
| Phase 1/2 | NCT06741644 Background | Feb 2025 → Jan 2027 expected | cancer | CStone Pharmaceuticals | Recruiting | No outcome recorded |
| Show all 114 trials opens the full record — a long page | ||||||
| Phase 2319 trials | ||||||
| Phase 2 | NCT07662928 Background | Sep 2026 → May 2031 expected | Burkitt lymphoma | AIDS Malignancy Consortium | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07698054 Background | Aug 2026 → Jan 2030 expected | small cell lung carcinoma | Henan Cancer Hospital | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06406465 Background | Jul 2026 → Jul 2027 expected | small cell carcinoma | National Cancer Institute (NCI) | Recruiting | No outcome recorded |
| Phase 2 | NCT07321912 Background | Jun 2026 → Jun 2031 expected | Ewing sarcoma, osteosarcoma | Milton S. Hershey Medical Center | Recruiting | No outcome recorded |
| Phase 2 | NCT07510594 Background | May → Dec 2026 expected | pulmonary large cell neuroendocrine carcinoma | Tianjin Medical University Cancer Institute and Hospital | Not yet recruiting | No outcome recorded |
| Show all 319 trials opens the full record — a long page | ||||||
| Phase 2/322 trials | ||||||
| Phase 2/3 | NCT06820957 Background | Nov 2025 → Dec 2027 expected | CIC-rearranged sarcoma, Ewing sarcoma, round cell sarcoma with EWSR1-non-ETS fusion, sarcoma with BCOR genetic alterations +1 | Children's Oncology Group | Active not recruiting | No outcome recorded |
| Phase 2/3 | NCT06756152 Background | Jul 2024 → Jul 2026 overdue | acute biphenotypic leukemia, bilineal acute myeloid leukemia, myelodysplastic syndrome | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | Recruiting | No outcome recorded |
| Phase 2/3 | NCT05991388 Background | May 2024 → May 2031 expected | B-cell non-Hodgkin lymphoma | University of Birmingham | Recruiting | No outcome recorded |
| Phase 2/3 | NCT05058651 Background | Jun 2022 → Oct 2028 | neuroendocrine carcinoma | National Cancer Institute (NCI) | Suspended | No outcome recorded |
| Phase 2/3 | NCT04254471 Background | Nov 2019 → May 2022 | small cell lung carcinoma | Haihe Biopharma Co., Ltd. | Unknown | No outcome recorded |
| Phase 2/3 | NCT03984448 Background | Oct 2019 → Apr 2028 expected | high grade B-cell lymphoma, high grade B-cell lymphoma with MYC and/ or BCL2 and/or BCL6 rearrangement | National Cancer Institute (NCI) | Active not recruiting | No outcome recorded |
| Phase 2/3 | NCT03992911 Comparator | Jun 2019 → Jun 2022 | neuroendocrine carcinoma | Peking University | Unknown | No outcome recorded |
| Phase 2/3 | NCT06105619 Comparator | Oct 2018 → Apr 2023 overdue | glioblastoma | Beijing Pearl Biotechnology Limited Liability Company | Active not recruiting | No outcome recorded |
| Phase 2/3 | NCT03588494 Background | Aug 2018 → Sep 2019 | — | Affiliated Hospital of North Sichuan Medical College | Unknown | No outcome recorded |
| Phase 2/3 | NCT03117751 Background | Mar 2017 → Sep 2026 expected | lymphoblastic leukemia, acute, with lymphomatous features | St. Jude Children's Research Hospital | Active not recruiting | No outcome recorded |
| Phase 2/3 | NCT03564704 Background | Feb 2016 → May 2021 | T-cell leukemia, adult acute lymphoblastic leukemia, lymphoblastic lymphoma | Nanfang Hospital, Southern Medical University | Unknown | No outcome recorded |
| Phase 2/3 | NCT03553238 Background | Feb 2016 → May 2020 | T lymphoblastic leukemia/lymphoma, T-cell leukemia, acute leukemia | Nanfang Hospital, Southern Medical University | Unknown | No outcome recorded |
| Phase 2/3 | NCT02772107 Background | Dec 2015 → Jun 2017 | small cell lung carcinoma | Chinese PLA General Hospital | Unknown | No outcome recorded |
| Phase 2/3 | NCT01228331 Comparator | Oct 2010 → Dec 2019 | leukemia | University Medical Center Hamburg-Eppendorf | Completed | No outcome recorded |
| Phase 2/3 | NCT01197560 Comparator | Sep 2010 → Jul 2013 | diffuse large B-cell lymphoma | Celgene Corporation | Completed | No outcome recorded |
| Phase 2/3 | NCT00930891 Background | Sep 2009 → Jul 2012 | small cell lung carcinoma | French Cooperative Thoracic Intergroup | Completed | No outcome recorded |
| Phase 2/3 | NCT00720109 Background | Jul 2008 → Dec 2014 | B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2), acute lymphoblastic leukemia | National Cancer Institute (NCI) | Completed | No outcome recorded |
| Phase 2/3 | NCT00539500 Background | Oct 2007 → Sep 2012 | neuroblastoma | M.D. Anderson Cancer Center | Terminated | No outcome recorded |
| Phase 2/3 | NCT00630565 Background | Jul 2006 → Jul 2022 | leukemia | Masonic Cancer Center, University of Minnesota | Terminated | No outcome recorded |
| Phase 2/3 | NCT00151242 Background | Jul 2004 → Aug 2011 | acute myeloid leukemia | University of Ulm | Completed | No outcome recorded |
| Phase 2/3 | NCT00070187 Background | Nov 2003 → Jun 2005 | lymphoma | Children's Oncology Group | Completed | No outcome recorded |
| Phase 2/3 | NCT00003643 Background | Oct 1998 → ? | extragonadal germ cell tumor, teratoma, testicular germ cell tumor | European Organisation for Research and Treatment of Cancer - EORTC | Unknown | No outcome recorded |
| Phase 3188 trials | ||||||
| Phase 3 | NCT07544654 Background | Jul 2026 → Dec 2029 expected | neuroendocrine carcinoma | Boehringer Ingelheim | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07678229 Comparator | Jul 2026 → Dec 2031 expected | mature T-cell and NK-cell non-Hodgkin lymphoma | Rong Tao | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07625644 Comparator | Jun 2026 → Jan 2030 expected | small cell lung carcinoma | SystImmune Inc. | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07472517 Background | Apr 2026 → Sep 2028 expected | small cell lung carcinoma | Boehringer Ingelheim | Recruiting | No outcome recorded |
| Phase 3 | NCT07502300 Comparator | Apr 2026 → Dec 2029 expected | small cell lung carcinoma | Sichuan Baili Pharmaceutical Co., Ltd. | Not yet recruiting | No outcome recorded |
| Show all 188 trials opens the full record — a long page | ||||||
| Phase 412 trials | ||||||
| Phase 4 | NCT06931145 Background | Apr 2025 → Apr 2027 expected | small cell lung carcinoma | Peking Union Medical College Hospital | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT05518383 Background | May 2022 → May 2025 overdue | Burkitt lymphoma, primary central nervous system lymphoma, primary mediastinal large B-cell lymphoma | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | Recruiting | No outcome recorded |
| Phase 4 | NCT04134247 Background | Nov 2019 → Nov 2021 | non-Hodgkin lymphoma | Shandong Provincial Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT04152577 Background | Jun 2019 → Oct 2021 | B-cell non-Hodgkin lymphoma | Shandong Provincial Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT03558412 Background | Jun 2018 → Dec 2019 | T-lymphoblastic lymphoma | Mingzhi Zhang | Unknown | No outcome recorded |
| Phase 4 | NCT02526823 Comparator | Aug 2015 → Dec 2019 | lymphoma | Shandong Provincial Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT01873807 Background | May 2013 → Dec 2015 | adult acute lymphoblastic leukemia | Nanfang Hospital, Southern Medical University | Unknown | No outcome recorded |
| Phase 4 | NCT01211002 Background | Oct 2010 → Dec 2011 | non-small cell lung carcinoma | Simcere Pharmaceutical Co., Ltd | Unknown | No outcome recorded |
| Phase 4 | NCT02319486 Background | Jan 2009 → Apr 2014 | retinoblastoma | Sun Yat-sen University | Completed | No outcome recorded |
| Phase 4 | NCT00199004 Background | Apr 2004 → Mar 2009 | adult acute lymphoblastic leukemia | Johann Wolfgang Goethe University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00198991 Background | Apr 2003 → Jun 2011 | adult acute lymphoblastic leukemia | Goethe University | Completed | No outcome recorded |
| Phase 4 | NCT00199147 Background | Jan 2000 → ? | acute myeloid leukemia | Johann Wolfgang Goethe University Hospital | Unknown | No outcome recorded |
| Phase not applicable29 trials | ||||||
| — | NCT07498959 Comparator | Mar 2026 → Mar 2031 expected | testicular seminoma | Sahlgrenska University Hospital | Recruiting | No outcome recorded |
| — | NCT06857747 Background | Mar → Dec 2025 | breast cancer | QIAO LI | Unknown | No outcome recorded |
| — | NCT06649448 Background | Oct 2024 → Dec 2025 overdue | neutropenia | Shandong Cancer Hospital and Institute | Not yet recruiting | No outcome recorded |
| — | NCT06480864 Background | Aug 2024 → Aug 2025 overdue | small cell lung carcinoma | Yunpeng Liu | Recruiting | No outcome recorded |
| — | NCT05922384 Background | Jul 2023 → Sep 2025 | HIV infectious disease, lymphoma | Affiliated Hospital of Guangdong Medical University | Unknown | No outcome recorded |
| — | NCT05863845 Background | Jun 2023 → Nov 2024 | diffuse large B-cell lymphoma | Ruijin Hospital | Unknown | No outcome recorded |
| — | NCT05936086 Comparator | Apr 2023 → Apr 2026 overdue | hemophagocytic syndrome | shifeng Lou | Recruiting | No outcome recorded |
| — | NCT05814718 Background | Apr 2023 → Dec 2025 | disease related to hematopoietic stem cell transplant | First Affiliated Hospital Xi'an Jiaotong University | Unknown | No outcome recorded |
| — | NCT05813132 Comparator | Nov 2022 → Dec 2023 | lymphoma | Rehab Werida | Completed | No outcome recorded |
| — | NCT05137522 Background | Jul 2021 → Jul 2023 | hemophagocytic syndrome | Beijing Friendship Hospital | Unknown | No outcome recorded |
| — | NCT04690231 Background | Dec 2020 → Mar 2021 | poisoning | Peking University People's Hospital | Completed | No outcome recorded |
| — | NCT03514849 Background | Aug 2018 → Mar 2021 | small cell lung carcinoma | Peng Zhang | Unknown | No outcome recorded |
| — | NCT02701231 Background | Nov 2015 → Dec 2020 | lung cancer | Chinese PLA General Hospital | Unknown | No outcome recorded |
| — | NCT01769911 Background | Feb 2015 → Feb 2019 | Burkitt lymphoma, Hodgkins lymphoma, MALT lymphoma, T-cell large granular lymphocyte leukemia +20 | Fred Hutchinson Cancer Center | Withdrawn | No outcome recorded |
| — | NCT02208583 Comparator | Jun 2014 → Dec 2016 | hormone-resistant prostate carcinoma | Tianjin Medical University Cancer Institute and Hospital | Unknown | No outcome recorded |
| — | NCT02015728 Background | Dec 2013 → Nov 2016 | brain cancer | Seattle Children's Hospital | Unknown | No outcome recorded |
| — | NCT01526603 Background | Mar 2012 → May 2023 | neuroblastoma | Masonic Cancer Center, University of Minnesota | Completed | No outcome recorded |
| — | NCT01408043 Background | Oct 2011 → May 2016 | Burkitt lymphoma, MALT lymphoma, T-cell large granular lymphocyte leukemia, Waldenstrom macroglobulinemia +18 | Case Comprehensive Cancer Center | Terminated | No outcome recorded |
| — | NCT02549261 Background | Mar 2011 → Apr 2012 | non-small cell lung carcinoma | Biotech Pharmaceutical Co., Ltd. | Unknown | No outcome recorded |
| — | NCT01184898 Background | Jul 2010 → Jan 2012 | acute myeloid leukemia | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | Completed | No outcome recorded |
| — | NCT00187096 Background | Sep 2005 → Feb 2012 | acute myeloid leukemia | St. Jude Children's Research Hospital | Completed | No outcome recorded |
| — | NCT00066482 Background | Jul 2004 → Apr 2007 | childhood germ cell tumor, extragonadal germ cell tumor | Children's Oncology Group | Completed | No outcome recorded |
| — | NCT00253552 Background | May 2004 → May 2006 | graft versus host disease, leukemia, myelodysplastic syndrome, myelodysplastic/myeloproliferative disease +3 | OHSU Knight Cancer Institute | Terminated | No outcome recorded |
| — | NCT00276640 Comparator | Apr 2004 → Dec 2015 | central nervous system neoplasm | International Society of Pediatric Oncology | Completed | No outcome recorded |
| — | NCT00049569 Background | Jan 2003 → Mar 2006 | T-cell childhood acute lymphocytic leukemia | National Cancer Institute (NCI) | Completed | No outcome recorded |
| — | NCT01702961 Background | Jun 2002 → Aug 2014 | Hodgkins lymphoma | Baylor College of Medicine | Completed | No outcome recorded |
| — | NCT00577096 Comparator | Oct 2001 → Jun 2004 | plasma cell myeloma | University of Arkansas | Completed | No outcome recorded |
| — | NCT00042367 Background | Apr 2000 → Dec 2005 | brain cancer | Baylor College of Medicine | Completed | No outcome recorded |
| — | NCT00006056 Background | Mar 2000 → ? | Chediak-Higashi syndrome, X-linked lymphoproliferative syndrome, graft versus host disease, secondary hemophagocytic lymphohistiocytosis | Fairview University Medical Center | Unknown | No outcome recorded |
| Phase not stated1 trial | ||||||
| — | NCT01085617 Background | Dec 2010 → Feb 2025 | leukemia, mouth disorder, mucositis | University College, London | Completed | No outcome recorded |
Evidence & citations 32 cited values
Every value below carries the sentence it was read from. 1,757 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | etoposide | “including but not limited to DHAP (dexamethasone, cisplatin, high-dose cytarabine), ESHAP (etoposide, methylprednisolone, high-dose cytarabine and cisplatin), DICE...” NCT04486391 ↗1677“Platinum (cisplatin or carboplatin)+VP-16: Cisplatin for injection 80-100mg/m2, divided into 3 days, the dose depends on tolerability, every 4 weeks as one cycle; carboplatin...” NCT07138001 ↗ “Standard Induction chemotherapy care included: vincristine, doxorubicin, and dexamethasone (VAD) (0.5 mg, 10 mg/m2, and 40 mg, respectively);dexamethasone,...” NCT00577096 ↗ “Control chemotherapy treatment will be chosen from any of the following standard-of-care chemotherapy drugs or combinations: * Carboplatin; * Irinotecan; * Etoposide; *...” NCT03632135 ↗ “The study investigates the tolerance and the efficacy of a new combination of five drugs consisting of propranolol (antiangiogenetic, anti-neuroblastic), Celecoxib (modulating...” NCT02641314 ↗ “Drugs:Chidamide and ICE regimen (ifosfamide, Mesna,Carboplatin and etoposide): Chidamide 20mg on d1,4,8,11;ifosfamide 1.2g/ m2,d1-4,ivg during 4 hours; Mesna 0.4g, 0,4,8 hours...” NCT02856997 ↗ “The purpose of this study is to find out what the response is and the side effects are with chemotherapy using a combination of drugs called D.T. PACE (Dexamethasone,...” NCT00107614 ↗ “Acceptable histology-specific PDC regimens include carboplatin plus paclitaxel or nab-paclitaxel (any histology), carboplatin/cisplatin plus pemetrexed (nonsquamous),...” NCT06865339 ↗ “bleomycin 10 units/m\^2 IV on Day 8 etoposide 200 mg/m\^2 IV on Days 1, 2 and 3 doxorubicin 35 mg/m\^2 IV on Day 1 cyclophosphamide 1250 mg/m\^2 IV on Day 1 vincristine 1.4...” NCT01118026 ↗ “All patients will receive 8 cycles of R-CHOEP immunochemotherapy every two weeks with the following doses per cycle: rituximab 375 mg/m², cyclophosphamide 750 mg/m²,...” NCT03399513 ↗ “Patients with a persistently positive interim-PET scan assigned to arm B2 will receive six blocks of the B-ALL protocol (rituximab, methotrexate, ifosfamide, etoposide,...” NCT00554164 ↗ “This is a phase 1/2 open label study to assess the safety and efficacy of pixantrone in combination with bendamustine, etoposide and , for CD20 positive B-cell lymphomas,...” NCT02678299 ↗ “The investigator prospectively evaluated the combination of Rituximab and Dexa-BEAM (dexamethasone, carmustine, etoposide, cytarabine, melphalan) followed by high dose therapy...” NCT02099292 ↗ “Clinical and safety outcomes of BeEAM (Bendamustine, Etoposide, Cytarabine, Melphalan) versus CEM (Carboplatin, Etoposide, Melphalan) in lymphoma patients as a conditioning...” PMID 39134959 ↗ Aug 2024 “Tucatinib in Combination With Oral Etoposide (VP16) - Trastuzumab in Patients With Metastatic HER2+ Breast Cancer After Progression Under Tucatinib-Capecitabine-Trastuzumab or...” NCT05955170 ↗ “Subjects will receive Nivolumab 360 mg every 3 weeks (Q3W) first day of each cycle plus Carboplatin AUC5 Q3W first day of each cycle plus Etoposide 100 day 1-3 of each cycle up...” NCT03980925 ↗ “Chemotherapy agents may include doxorubicin, ifosfamide, docetaxel, CHOP regimen, etoposide, cyclophosphamide and vincristine which will be administered as per standard of care...” NCT04570423 ↗ “R-ICE:rituximab 375mg/m\^2 before chemotherapy, ifosfamide 5g/m\^2 24 hours continuous infusion (CI) on Day 2+mesna, carboplatin area under the curve (AUC)5 Day 2, maximum dose...” NCT03391466 ↗ “Chemotherapy is based upon regimes with well known effectiveness in Hodgkin lymphoma. (i.e. ABVD: doxorubicin, bleomycin, vinblastine and dacarbazine and ESHAP: Etoposide,...” NCT03500133 ↗ “Patients received a maximum of 2 cycles of the intravenous (IV) 5-drug regimen (clofarabine, etoposide,cyclophosphamide, PEG-asparaginase, and vincristine) plus intrathecal...” NCT00991133 ↗ “Radiotherapy Technique: IMRT Total dose: 50 Gy Per fraction: 2 Gy Chemotherapy: q3w Dexamethasone 40 mg d1-4 Ifosfamide 1200mg/m2 d1-4 Etoposide 60 mg/m2 d1-4 Cisplatin 20mg/m2...” NCT01667302 ↗ “The chemotherapy entails the administration of multiple cycles of infusional doxorubicin, etoposide and vincristine chemotherapy (total of 3), alternating with cycles of...” NCT00001430 ↗ “Six cycles of standard induction chemotherapy consisting of cyclophosphamide, vincristine, doxorubicin (or epirubicin), etoposide, and cisplatin administered according to the...” NCT07688252 ↗ “Topo II inhibitor Etoposide (VP-16) can reduce cell survival, enhance DNA damage, and delay resistance in Osimertinib-resistant cells, suggesting a potential combination...” NCT06436144 ↗ “Induction treatment with: 4 cycle of Vincristine (9mg/,2), Dactinomycin (6mg/m2), Doxorubicin (160mg/m2), Cyclophosphamide (2.4g/m2), Ifosfamide (18g/M2) and Etoposide...” NCT02063022 ↗ “If the postoperatively pathological examination of the patient is confirmed to be in pT1-2N0 stage, a single postoperative adjuvant chemotherapy (combining etoposide with...” NCT03514849 ↗ “Dosing of chemotherapy is etoposide 90mg/m² body surface area (BSA) day 1-3 in combination with cisplatin 75mg/m² BSA on day 1 or carboplatin area under the curve (AUC) 5 mg/ml...” NCT06223711 ↗ “Chemotherapy agents for consolidation include dexamethasone, vincristine, methotrexate, PEG-asparaginase (Erwinia asparaginase when PEG-asparaginase is not available),...” NCT04501614 ↗ “Used drugs are rituximab,cyclophosphamide, prednisone, dexamethasone, vincristine, methotrexate, iphosphamide, teniposide, etoposide, dexamethasone, cytarabine,adriamycin,...” NCT01290120 ↗ “This trial is to evaluate the efficacy of concurrent chemoradiotherapy with cisplatin followed by VIPD (etoposide, ifosfamide, cisplatin, dexamethasone) in localized NK/T-cell...” NCT00418535 ↗ “The other drug must contain one of the following: etoposide, vinorelbine, vinblastine, pemetrexed, taxanes (e.g., paclitaxel, docetaxel, albumin paclitaxel, paclitaxel...” NCT06424899 ↗ “Etoposide is given at a dose of 100 mg/m2 intravenous infusion over a 2 hour period every 12 hours on treatment days -5, -4, -3, and -2, for a total of 8 doses (Day 0 = stem...” NCT00058292 ↗ “Participants on mitoxantrone, etoposide, cytarabine(MEC) will receive 8 mg/m\^2 of mitoxantrone daily by IV for 3 days (day 1 to 3), 100 mg/m2 of etoposide daily by IV for 7...” NCT05876832 ↗ “Rituximab combined with Chemotherapy (Rituximab, Cyclophosphamide, doxorubicin, Vincristine, Prednisone, Ifosfamide, Gemcitabine, cisplatin, Carboplatin, Etoposide, MESNA,...” NCT07187960 ↗ “Patients will be treated with carboplatin or cisplatin with etoposide, paclitaxel, albumin-bound paclitaxel or pemetrexed at the discretion of the treating thoracic medical oncologist.” NCT04905316 ↗ “Other drugs are administered at starting doses (Etoposide 50 mg/m2 (Days 1-4), Doxorubicin 10 mg/m2 (Days 1-4), Vincristine 0,4 mg/m2 (Days 1-4) and Cyclophosphamide 750 mg/m2 (Day 5).” NCT06871007 ↗ “Day 1 of each cycle will consist of an infusion of rituximab followed by the initiation of a 96-hour continuous infusion of etoposide, doxorubicin, and vincristine and oral prednisone.” NCT00799136 ↗ “Etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab (EPOCH-R) followed by idiotype vaccine and granulocyte-macrophage colony-stimulating factor (GM-CSF).” NCT00005780 ↗ “Rituximab 375 mg/m2 d0; Lenalidomide 25mg/d d1-10; Ifosfamide 5g/m2 d2; Carboplatin calculate according to AUC=5 (single dose ≤800 mg); Etoposide 100mg/m2 d1-3; Tirelizumab 200mg d6.” NCT05050630 ↗ “Concurrent chemoradiation will be with platinum-based chemotherapy (cisplatin or carboplatin, with etoposide, taxane, or pemetrexed) selected at the treating physician's discretion.” NCT04364048 ↗ “Rituximab (500 mg/m2 IV once)+ Ifosfamide (1500 mg/m2 IV daily over 3 hours)+ Etoposide (60 mg/m2 IV daily over 1 hour), and Cytarabine (2 grams/m2 IV over 3 hours for 4 doses)” NCT00392990 ↗ “High intensity: intermediate or high dose cytarabine (HiDAC); mitoxantrone, etoposide, and cytarabine (MEC); or fludarabine, cytarabine, G-CSF, +/- idarubicin (FLAG/FLAG-Ida).” NCT02920008 ↗ “Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas With Secondary Involvement of the Central Nervous System (CNS)” NCT03964090 ↗ “Rituximab 375mg/m2 at day 0, Meththylprednisolone 500mg IV at days 1 to 5, Etoposide 40mg/m2 at days 1 to 4, Cisplatin 25mg/m2 at days 1 to 4, Cytarabine 2000mg/m2 at day 5.” NCT01278602 ↗ “IP: cisplatin 50mg/m2 and etoposide 100mg/m2, weekly, 4 times; 14 days later IV: paclitaxel 175mg/m2 plus carboplatin AUC 5 or docetaxel 60-75mg/m2 plus carboplatin AUC 5” NCT01669226 ↗ “Vincristine 1.4 mg/m2 (2 mg cap) IV on Day 1, Doxorubicin 10 mg/m2/day CIVI on Days 1-4, Etoposide 50 mg/m2/day CIVI on Days 1-4, Cyclophosphamide 750 mg/m2 IV on Day 5.” NCT04002947 ↗ “Gemcitabine 1.0 g/m² on day 1, etoposide 60 mg/m² on days 1-3, pegaspargase 2000 IU/m² on day 4, and dexamethasone 40 mg on days 1-4, repeated every 21 days for 1 cycle.” NCT07678229 ↗ “Vincristine, etoposide, carboplatin, and cyclophosphamide have been used in many protocols for brain tumors but the result was very poor in refractory or relapsed cases.” NCT01535183 ↗ “Temozolomide, etoposide, doxil, dexamthasone, ibrutinib (TEDDI) given every 21 days for cycles 2-6 (Arm 1-A); given every 21 days for cycles 1-6 (Arms 1-B, 2, 3 and 4)” NCT02203526 ↗ “Concurrent with standard of care platinum doublet based chemotherapy (cisplatin + etoposide), radiation treatment plan will be delivered in three sequential phases” NCT04952480 ↗ “Intensive chemotherapy Cladribine-cytarabine-etoposide -venetoclax sequential with fludarabine, busulfan and melphalan or fludarabine and total marrow irradiation” NCT05870995 ↗ “Platinum based chemotherapy including cisplatin and etoposide, carboplatin and paclitaxel or cisplatin and pemetrexed (for patients with non-squamous histology).” NCT03663166 ↗ “Clofarabine intravenously 2-hour infusion,dose 40 mg/m2, followed by Etoposide (VP 16)100 mg/m2 i.v. over 2 hours and Cyclophosphamide 440 mg/m2 i.v. over 1 hour” NCT01385891 ↗ “Radiochemotherapy: Cisplatin (75 mg/m² (BSA) D1#) or alternatively Carboplatin (AUC 5 D1) and Etoposide (100 mg/m² (BSA) D1-3) once every 3 weeks for 4-6 cycles” NCT04602533 ↗ “Etoposide will be administered by IV infusion over 60 minutes following carboplatin administration, during the induction phase on Day 1 through 3 of each cycle.” NCT04028050 ↗ “* EA±Mitox regimen: etoposide injection 100 mg/m2, cytarabine injection 100-150 mg/m2, mitoxantrone injection 8 mg/m2 QD IV for 5 consecutive days (Days 1-5).” NCT06387069 ↗ “Ifosfamide (day 1-3: 1.900mg/m² iv), epirubicin (day 1: 75 mg/m² iv), etoposide (day 1-3: 120 mg/m² iv) and G-CSF (day 5 until end of apheresis: 5µg/kg sc)” NCT02288741 ↗ “Each cycle of NICE consists of four doses of hu3F8, five doses of GM-CSF, one dose of carboplatin, and 3 doses each of ifosfamide and etoposide (table 2).” NCT06438614 ↗ “Standard Chemotherapy (which includes cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate, 6-mercaptopurine, etoposide, and cytarabine” NCT03319901 ↗ “This study aimed to investigate the efficacy and safety of Chidamide together with Etoposide and methylprednisolone for hemophagocytic lymphohistiocytosis” NCT05137522 ↗ “Methotrexate 3g/m2, 3-hour infusion Day 1; Etoposide 100mg/m2, Days 4 to 5; Ifosfamide 800 mg/m2, Days 1 to 5; Cytarabine 150 mg/m2, q12h Days 4 to 5;” NCT04881838 ↗ “The 5 chemotherapy drugs used in the Induction part of treatment are vincristine, cisplatin, cyclophosphamide, etoposide and high-dose methotrexate.” NCT02875314 ↗ “Patients take prednisone by mouth on days 1 to 5 and etoposide, doxorubicin, and vincristine as a 96-hour infusion through a vein over days 1 to 5.” NCT00114738 ↗ “first-line chemotherapy must be platinum-based: cisplatin(75mg/m2 for d1) or carboplatin(AUC 5 for d1) combined with etoposide(100mg/m2 for d1-d3)” NCT02772107 ↗ “Dose Adjusted - Etoposide Prednisone Vincristine Cyclophosphamide Doxorubicin - Rituximab (DA-EPOCH-R) and nivolumab are both feasible treatments.” NCT03620578 ↗ “MK-0646 should be given 1st followed within 30-60 minutes by cisplatin and then etoposide for cycles which include both MK-0646 and chemotherapy.” NCT00869752 ↗ “R-HDS : Rituximab supplemented high-dose (Cyclophosphamide,Ara-C, Methotrexate, Etoposide, Cis-Platin) sequential chemotherapy with autografting.” NCT00355199 ↗ “Mitoxantrone hydrochloride liposome, carmostine, etoposide and cytarabine will be used as conditioning regimen for ASCT in the lymphoma patients.” NCT05681403 ↗ “This phase II study aimed to evaluate the efficacy and safety of oral niraparib plus etoposide in platinum resistant/refractory ovarian cancer.” PMID 39074931 ↗ Nov 2024 “Carmustine (B) also known as BCNU Etoposide (E) Cytarabine (A) also known as Ara-C and cytosine arabinoside Melphalan (M) also known as alkeran” NCT00574509 ↗ “platinum-based chemotherapy (carboplatin \[area under the curve (AUC) 5 mg/mL per min, IV\] and etoposide \[100 mg/m2, IV, D1-D3\] for ES-SCLC)” NCT06620796 ↗ “ADE chemotherapy Cytarabine (100mg/m2 d1-d10 BD), Daunorubicin (50mg/m2 d1-d3) and Etoposide (100 mg/m2 d1-5) over a period of 10 days” NCT03053206 ↗ “The recommended chemotherapy is based on the current reference combination of platinum (cisplatin or carboplatin) and etoposide (VP16).” NCT04268121 ↗ “A Phase II Trial of High-dose Bendamustine, Etoposide, Cytarabine, and Melphalan (BeEAM) in the Up-front Treatment of Multiple Myeloma” NCT02416206 ↗ “Etoposide 50 (50-150) mg/m2 IV daily for 3-5 days every 21 to 28 days OR 100 (50 300) mg/m2 PO daily for 3-5 days every 21 to 28 days” NCT00117598 ↗ “Etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin (EPOCH) plus rituximab and campath every 3 weeks for up to 6 cycles” NCT01030900 ↗ “Etoposide 75mg/m2/iv over 90min through day 1 to day 4 and cisplatin 25mg/m2/iv over 30min through day 1 to day 3, repeat Q 3weeks.” NCT02738723 ↗ “Etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin (EPOCH) + Alemtuzumab (Campath) every 3 weeks for up to 6 cycles.” NCT00069238 ↗ “In course one with cytarabine and etoposide either mitoxantrone (standard) or DaunoXome (experimental) is given as anthracycline.” NCT01828489 ↗ “Bevacizumab 15mg/kg IVF on D1, Etoposide 70 mg/m2 IVF QD, D2-4, Cisplatin 70 mg/m2 IVF on D2, repeat every 3 weeks, for 3 cycles” NCT02185352 ↗ “Cisplatin 50 mg/m2 administered on days 1,8, 29, 36; Etoposide 50 mg/m2 administered on days 1-5 and then again days 29-33” NCT01416961 ↗ “short-course etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin with dose-dense rituximab (SC-EPOCH-RR)” PMID 20130244 ↗ Feb 2010 “Semustine, 300 mg/m2,-6d; Etoposide, 100 mg/m2,-5~-2d; Cytarabine, 100mg/m2,q12h,-5~-2d; Cyclophosphamide, 1.5g/m2,-5~-2d” NCT04880746 ↗ “conventional chemotherapy (cyclophosphamide, doxorubicin, vincristine, etoposide, prednisone) and rituximab (R-CHOEP-14)” PMID 23168367 ↗ Nov 2012 “alternating cyclophosphamide, vincristine and idarubicin alternating with another 3 cycles of carboplatin and etoposide” NCT03475121 ↗ “IVE, ifosfamide 2000 mg/m2 on days 1-3, epirubicin 70 mg/m2 on day 1, and etoposide 100 mg/m2 on days 1-3 every 21 days” PMID 32349779 ↗ Apr 2020 “etoposide (100 mg per square meter of body-surface area, administered intravenously on days 1 through 3 of each cycle)” NCT04487756 ↗ “Etoposide 50mg/m2, ivgtt, d1-d5; cisplatin 50mg/m2, ivgtt, d1 and d8, every 28 days for a cycle, a total of 2 cycles” NCT02215356 ↗ “6 courses of platinum/etoposide/bevacizumab/camrelizumab and a total period of 12 months bevacizumab/camrelizumab” NCT04635956 ↗ “initiation : etoposide 100mg/m2/d i.v. + cyclosporine 2mg/kg i.v. q 12hours + dexamethasone 20mg/m2/d i.v. (D1-3)” NCT01547143 ↗ “serplulimab 300mg, d1, q3w, iv. etoposide 100 mg/m2, d1-3, q3w, iv. carboplatin AUC 5 (up to 750mg), d1, q3w, iv.” NCT05957510 ↗ “Chemotherapy:vincristine,1.5mg/m2;carboplatin,560mg/ m2;etoposide,150 mg/ m2.monthly for the first three months.” NCT05080010 ↗ “The first Peripheral Blood Stem Cell Rescue will consist of Etoposide, Carboplatin, Cyclophosphamide, and Mesna.” NCT00179816 ↗ “3 cycles of lenalidomide 5mg, etoposide, methylprednisolone, cisplatin, cytarabine and rituximab every 3 weeks.” NCT02340936 ↗ “R-DA-EPOCH (rituximab and dose adjusted-etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin)” NCT03023878 ↗ “Carboplatin AUC 5 d1 + Etoposide 100 mg/m² d1-3 + thoracic involved-field radiotherapy (IFRT), q3w × 4 cycles.” NCT07559786 ↗ “Immuno-chemotherapy regimen included etoposide, cisplatin, iparomlimab and tuvonralimab, and thymosin alpha 1.” NCT07103408 ↗ “Chemotherapy:vincristine,1.5mg/m2;carboplatin,560mg/ m2;etoposide,150 mg/ m2.monthly for the first six months” NCT02137928 ↗ “Patients will receive three cycles of atezolizumab in combination with carboplatin/cisplatin plus etoposide.” NCT06768307 ↗ “semustine 250mg/m2 PO d1; etoposide 200mg/m2 IV d2-5; cytarabine 400mg/m2 IV d2-5; melphalan 140mg/m2 IV d6.” NCT05504603 ↗ “R-HDS (cyclophosphamide, cytarabine, and etoposide) supported by autologous stem-cell transplantation (ASCT)” PMID 26282634 ↗ Aug 2015 “Etoposide combined with cisplatin or carboplatin, administered every three weeks for a total of four cycles.” NCT06719700 ↗ “Etoposide: total 100 mg/m2, once a day, continuous intravenous drip for more than 3 hours, days 1 to 3, q3w” NCT05668767 ↗ “dose-adjusted etoposide, doxorubicin, cyclophosphamide, vincristine, prednisone, and rituximab (DA-EPOCH-R)” PMID 32453640 ↗ May 2020 “Induction therapy: TQB2450 1200mg, d1+carboplatin (AUC5) , d1+ etoposide 100mg/m2, d1,d2,d3, q3w, 4 cycles.” NCT04539977 ↗ “Etoposide 100 mg/m2/d d 1 - 4 CI Cisplatin 25 mg/m2/d d 1 - 4 CI Ara C l g/m2 d 5 Dexamethasone 40 mg d 1-5” NCT00580372 ↗ “bleomycin, etoposide, adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone (BEACOPPesc)” NCT01652261 ↗ “infused etoposide, doxorubicin, and cyclophosphamide with vincristine, prednisone, and rituximab (EPOCH-R)” PMID 24224624 ↗ Nov 2013 “ifosfamide 1500 mg/m² iv days 1 - 4, etoposide 125 mg/m² iv days 1 and 4, and adriamycin 50 mg/m² iv day 1” NCT01382030 ↗ “Chemotherapy: Cisplatin (50 mg/m2) on days 1, 8, 29, and 36 and etoposide (50mg/m2) on days 1~5 and 29~33.” NCT03588494 ↗ “ESHAP (etoposide, methylprednisolone, cisplatin, cytosine arabinoside) chemotherapy was invented in 1994.” NCT00930605 ↗ “SHR-1316(Adebrelimab),20mg/kg,+Cisplatin 75mg/m2, d1+ etoposide 100mg/m2, d1,d2,d3, q3w, iv, 4 cycles.” NCT05496166 ↗ “Etoposide - 100 mg/m\^2 IV over approximately 1 hour each day for 3 days every 21 days for 2-6 cycles.” NCT03264131 ↗ “Etoposide: 80-100mg/m², intravenous infusion, given at week 1, 4, 7, 10, 13, 16, a total of 6 cycles.” NCT06371482 ↗ “Chemotherapy options include carboplatin/ paclitaxel and cisplatin/etoposide per standard of care.” NCT03745222 ↗ “Etoposide will be administered intravenously at a dose of 100 mg/m² on days 1 to 3 of each cycle.” NCT06784206 ↗ “Etoposide: (100 mg/m2) administered intravenously on Days 1, 2, and 3 of each cycle for 4 cycles” NCT04952597 ↗ “One bridging chemotherapy cycle consists of five days of therapy using Carboplatin and etoposide” NCT07291102 ↗ “ETOPOSIDE Dosage: total 900 mg/m2, IV, which is 150 mg/m2 during 12 hours (days +1, +2 and +3).” NCT01361191 ↗ “50 mg/m2 per day as a continuous intravenous infusion from day 1 to day 4 (96 h) for etoposide” PMID 37011643 ↗ Mar 2023 “PD-1 inhibitor (tirelizumab) combined with ifosfamide, carboplatin and etoposide (ICE) regimen” NCT04860674 ↗ “BCNU, etoposide, cytarabine and melphalan (BEAM) chemotherapy are given after 90Y-daclizumab” NCT01468311 ↗ “neoadjuvant chemotherapy is based on the combination of etoposide and cisplatin/carboplatin.” NCT03523234 ↗ “Etoposide, Prednisone, Doxorubicin, Cyclophosphamide, Vincristine, Rituximab, Pegfilgrastim” NCT02142049 ↗ “dose-adjusted etoposide, doxorubicin, and cyclophosphamide with vincristine and prednisone” NCT05996185 ↗ “CE: Carboplatin AUC=8 IV daily days -4 to -2, Etoposide 400mg/m\^2 IV daily days -4 to -2” NCT06418789 ↗ “CYVE Consolidation (2 cycles): Cytarabine, High-Dose Ara-C, Etoposide, Rituximab, G-CSF.” NCT01046825 ↗ “etoposide, methotrexate, actinomycin D/cyclophosphamide, vincristine, alternate weekly” NCT05139095 ↗ “Drug: Etoposide Etoposide (60 mg/ m2) will be administered by an intravenous infusion” NCT06433362 ↗ “Brentuximab Vedotin Etoposide Cyclophosphamide Doxorubicin Dacarbacine Dexamethasone” NCT06919679 ↗ “NOVE-HiDAC consists of mitoxantrone, etoposide, and modified high-dose cytarabine.” NCT01222143 ↗ “Etoposide 100 mg once daily orally d 1-7 + cisplatin 60-75 mg/m2 d1 every 3 weeks.” NCT04055038 ↗ “BeEAC (Bendamustine, Cytarabine, Etoposide, Cyclophosphamide) conditioning regimen” NCT03315520 ↗ “Fludarabine 150mg/m2, busulfan 6.4mg/kg, melphalan 100mg/m2 and etoposide 600mg/m2” NCT04897139 ↗ “followed by high dose chemotherapy with treosulfan, etoposide and cisplatin (TEC)” NCT00384553 ↗ “etoposide: 100mg/m2/d vgtt q12h D-7-D-4 cytarabine: 200mg/m2/d vgtt q12h D-7-D-4” NCT06652165 ↗ “2. PE (Cisplatin 50mg/m2 on days 1,8,29,36 Etoposide 80mg/m2 days 1-3 and 29-31)” NCT01336543 ↗ “vincristine, cyclophosphamide, cisplatin, etoposide with or without methotrexate” NCT06193759 ↗ “Etoposide :50 mg/m(2) per day continuous IV infusion over 24 hours on days 1-4” NCT00520130 ↗ “Etoposide (E), intravenous infusion, 100mg/m2, D1-5, even cycle administration” NCT06699472 ↗ “For cycle 1/4/5/6. Etoposide 100mg/m2, d1-3, q3w; Cisplatin 25mg/m2 d1-3, q3w.” NCT04882033 ↗ “chemotherapy:vincristine,1.5mg/m2;carboplatin,560mg/ m2;etoposide,150 mg/ m2.” NCT01899066 ↗ “rituximab, cyclophosphamide, doxorubicin, etoposide, vincristine, prednisone” NCT03293173 ↗ “Adebrelimab (1200 mg, Day 1) + Etoposide (100 mg/m2, Days 1-3) + Carboplatin” NCT06764368 ↗ “Etoposide (100 mg/m\^2) should be administered intravenously over 60 minutes” NCT04878016 ↗ “vincristine 1.4 mg/m2 day 1 etoposide 100mg/m2 days 1,2,3 Prednison 100 mg” NCT01502982 ↗ “During Cycle 2, participants will receive etoposide and cyclophosphamide.” NCT05326516 ↗ “2 cycles of IV P-ICE (pembrolizumab, ifosfamide, carboplatin, etoposide)” NCT04838652 ↗ “Mitoxantrone 8mg/m2 d1-5, etoposide 100mg/m2 d1-5, cytarabine 1g/m2 d1-5” NCT05657639 ↗ “Etoposide 100mg/m\^2 d1-3+ cisplatin 75mg/m\^2 d1-3 or Carboplatin AUC5” NCT07172412 ↗ “etoposide 100 mg/m² on Days 1-3 of each of the first four 21-day cycles” NCT00403403 ↗ “Etoposide 100 mg/m2 i.v. every 12 hours in 250 ml dextrose 5% solution” NCT01827605 ↗ “6 cycles of CEV chemotherapy (carboplatin, etoposide, and vincristine)” PMID 39432296 ↗ Nov 2024 “Etoposide 200 mg/m2/day intravenously once daily from day -5 to day -2” NCT03187210 ↗ “Etoposide: 50 mg/m2/day, in continuous 24-hour infusion, days 1 to 4.” NCT01066429 ↗ “Polatuzumab Vedotin x 1; Rituximab x 1; Cytarabine x 5; Etoposide x4;” NCT05253495 ↗ “Regimen 1: etoposide 75mg/m2 d1-5 + cisplatin 75 mg/m2 day1/ day1-2.” NCT02883543 ↗ “Etoposide 200 mg/m2 and Cytarabine 400 mg/m2 for 4 days (D-6 to D-3)” NCT02008006 ↗ “Etoposide 50mg/ m2, Epirubicin 15mg/ m2, Vincristine 0.4mg/ m2, d1-4” NCT05164770 ↗ “R-ICE consists of rituximab, etoposide, carboplatin and ifosfamide.” NCT03450343 ↗ “Tislelizumab in Combination With Chemotherapy(etoposide/cisplatin )” NCT06851819 ↗ “Etoposide: 100 mg/m², intravenous infusion, Days 1-3, every 3 weeks” NCT07381543 ↗ “alternating prolonged exposure to topotecan and etoposide (VP-16)” NCT00250094 ↗ “SCLC patients will receive six cycles of cisplatin and etoposide.” NCT02701231 ↗ “etoposide 100mg/m\<2\> IV day 1 and 200mg/m\<2\> orally days 2, 3” NCT00388960 ↗ “Etoposide, 300 mg/m²/d in two daily injections at 12-h intervals” NCT01966913 ↗ “ESHAP (etoposide, methylprednisolone, cytarabine, and cisplatin)” NCT00568815 ↗ “vincristine,1.5mg/m2;carboplatin,560mg/ m2;etoposide,150 mg/ m2” NCT02319486 ↗ “plus etoposide 100 mg/m2 1-3q21- for 4 cycles (Induction Phase)” NCT05623319 ↗ “etoposide, 200 mg/m2 intravenously daily from day -5 to day -2” NCT02278796 ↗ “Drug: Etoposide Etoposide (65 mg/m2) on day 2-4, every 3 weeks” NCT06953739 ↗ “* Etoposide 100 mg/mq, e.v. days 1,2,3 (if ≥70 years 75 mg/mq)” NCT02371161 ↗ “IE: ifosfamide 1.8 g/m2/d d1-3; etoposide 100 mg/m2/d d1-3 Q2w” NCT04824352 ↗ “VECP(Vindesine Sulfate, Etoposide, Carboplatin, Prednisolone)” NCT01173887 ↗ “Either irinotecan or temozolomide or carboplatin or etoposide” NCT05718466 ↗ “Etoposide 100 mg/m² IV infusion over 1 hour on day 1,2 and 3” NCT04325425 ↗ “Belinostat at 400 mg/m\^2/day plus Cisplatin plus Etoposide” NCT06406465 ↗ “VIA: VP-16 (Etoposide),Ifosfamide,Mesna, Cytarabine (ara-C)” NCT01083342 ↗ “50 mg per day of Etoposide orally for 21 consecutive days.” NCT00176605 ↗ “Etoposide 75 mg/m²/d, Day 1-4 Ifosfamide 3 g/m²/d, Day 1-4” NCT03643133 ↗ “Drug: etoposide Given IV Other Names: EPEG VP-16 VP-16-213” NCT05922384 ↗ “Etoposide, IV infusion for 96 hours on days 1, 2, 3, and 4” NCT02700022 ↗ “Chidemide,carmustine, etoposide, cytarabine, and melphalan” NCT05931263 ↗ “etoposide - 100 mg/m\^2 on days 1, 2 and 3 of dosing cycle” NCT00823719 ↗ “etoposide (Day1-3 100mg/m2 for squamous cell lung cancer)” NCT02947113 ↗ “vinca alkaloids, steroids, etoposide or alkylating agents” NCT02013167 ↗ “IV Etoposide 100 mg/m\^2 on Days 1-3 of each 21-day cycle” NCT03212937 ↗ “Etoposide (VP-16) 100 mg/m2 twice a day (Days -5 to -2)” NCT00329030 ↗ “Patients treated with bevacizumab and VP-16 (etoposide)” NCT00613028 ↗ “Etoposide (IV, 200 mg/m2 every 12 h on days -5 and -4)” NCT00336843 ↗ “Oral Etoposide Combined With Anlotinib and Envafolimab” NCT05685550 ↗ “Idarubicin, Etoposide, Cytarabine, ATRA, Pegfilgrastim” NCT00893399 ↗ “Prednisone, Cyclophosphamide, Etoposide, Procarbazine” NCT00151281 ↗ “Etoposide 100mg/m2 D1-3 of each 21-day cycle IV drip;” NCT05760053 ↗ “Chemoimmunotherapy: Etoposide 80-100mg/m2 day 1, 2, 3” NCT06479473 ↗ “Etoposide 100 mg / m² / day for 4 days (J-12 to J-9)” NCT03035422 ↗ “etoposide 100 mg/m² IV D1-3 + carboplatin AUC 5-6 IV” NCT07001995 ↗ “Etoposide (200 mg/m2 once daily i.v. on days -8, -6)” NCT01342237 ↗ “2. etoposide 60mg/m\^2 on day 1-3, intravenous drip;” NCT06314334 ↗ “Etoposide injection: 100mg/m2, IV infusion, day 1\~3” NCT02800447 ↗ “Etoposide 100 mg/m\^2 by vein, Over 1 Hour x 5 Days” NCT00500890 ↗ “1 cycle of Etoposide Cisplatine (EP) chemotherapy.” NCT05529251 ↗ “cytarabine and/or etoposide and/or pegasparaginase” NCT03236857 ↗ “apatinib po; ifosfamide ivgtt ; etoposide ivgtt .” NCT05277480 ↗ “procarbazine, etoposide and prednisone (BEACOPP)” PMID 28601705 ↗ Jun 2017 “Etoposide 100 mg/m²/day for 4 days (J-12 to J-9)” NCT03079089 ↗ “etoposide (100 mg/m²) infusion (1 hr) for 3 days” NCT02172872 ↗ “standard-dose etoposide 80-100 mg/m² on days 1-3” NCT06597513 ↗ “Regimen B :IVAC:ifosfamide,etoposide,cytarabine.” NCT03558412 ↗ “Etoposide 200mg/m2 intravenous infusion, day2-5” NCT06682130 ↗ “Cisplatin, Carboplatin, Flourouracil, Etoposide” NCT01525927 ↗ “Etoposide 150 mg/m2/day iv over 3 hours (d1-4)” NCT00844298 ↗ “Etoposide 100 mg/m2/day IV x 5 days (D1 to D5)” NCT05705687 ↗ “Etoposide 165 mg/m2 IV infusion - days 1, 2, 3” NCT01726374 ↗ “etoposide 200 mg/m2 intravenously on days 1-3” PMID 30658935 ↗ Jan 2019 “plus Etoposide 60mg/m2 OR on Day15 through 19” NCT03576378 ↗ “BEAM (BCNU, Etoposide, Cytarabine, Melphalan)” NCT02858258 ↗ “Etoposide 2 x 100 mg/m², iv, day -6 to day -3” NCT00946374 ↗ “etoposide infusion100 mg/m2/day on day 1 - 3” NCT02684708 ↗ “Etoposide: 100 mg/m² infused over 60 minutes” NCT02265770 ↗ “etoposide 100mg/M2 BID on days -5 through -2” NCT00572013 ↗ “Etoposide-cisplatin-doxorubicin or mitotane” NCT06333314 ↗ “Mitoxantrone - Etoposide - Cytarabine (MEC)” NCT06713837 ↗ “Etoposide 50 mg/m2 D1-5, D29-33,IV infusion” NCT03945227 ↗ “Etoposide 40 mg/m2, Continuous infusion 1-4” NCT00113919 ↗ “topotecan, cyclophosphamide, and etoposide” NCT03042429 ↗ “Etoposide: 50 mg/m2 given CIV from day 1-4” NCT04992377 ↗ “Etoposide 200 mg/m2 from day -5 to day -2” NCT01296256 ↗ “Etoposide: 100 mg/m2 (days 1, 2, 3, 4, 5)” NCT05827549 ↗ “etoposide 100 mg/m2 was administered day1” NCT05315336 ↗ “Etoposide: 100mg/m2/d ivgtt q12h D-7-D-4” NCT06652139 ↗ “etoposide 150 mg/m(2) i.v. Days -5 to -3” PMID 23242601 ↗ Dec 2012 “etoposide 100 mg/m2 on Days 1, 2, and 3)” NCT01453205 ↗ “Drug: Etoposide 4-6 cycles every 3 weeks” NCT04449861 ↗ “Etoposide: 100mg/m2/d ivgtt q12h D-6-D-3” NCT05367856 ↗ “Etoposide: 100mg/m2 IV d1,Q3W ,2 cycles” NCT05904015 ↗ “3. etoposide: 40mg/m2 D1-4, intravenous” NCT04065308 ↗ “Etoposide 100mg/ms iv from day +1 to +3” NCT02223208 ↗ “etoposide IV on day 1 of weeks 3 and 7” NCT00846742 ↗ “Etoposide (E) 125mg/m2/day IV over 1hr” NCT01858922 ↗ “etoposide 100 mg/m2/D IV from D1 to D3” NCT00970385 ↗ “BCNU, Etoposide, Cytarabine, Melphalan” NCT03113162 ↗ “Etoposide, 1.7 mg/kg p.o. qd x 21 days” NCT00042367 ↗ “Etoposide, 100mg/m2 iv, day 2 to day 4” NCT02764281 ↗ “Etoposide, 60mg/m2 IV, day 1 to day 3” NCT02733458 ↗ “Etoposide 150mg/m\^2/d qd IVD d-5\~-2” NCT03629873 ↗ “Etoposide 75 mg/m² D1 to D3, 4 cycles” NCT00930891 ↗ “Etoposide, IV, D15 to D19, 100mg/m²/d” NCT03011528 ↗ “High dose etoposide, Cyclophosphamide” NCT00460421 ↗ “Etoposide 100 mg/m2/day IV 4, 5 days” NCT02842931 ↗ “etoposide 50 mg 2, ivgt, D1-5, 29-33” NCT04182698 ↗ “Etoposide 100 mg/m2/day IV 4, 5 days” NCT03479918 ↗ “Etoposide, 100mg /m², D1-3, IV, Q3W.” NCT07069270 ↗ “Etoposide (100 mg/m² IV on Days 1-3)” NCT06554535 ↗ “Chemotherapy (Carboplatin-Etoposide)” NCT06812260 ↗ “Etoposide \[40 mg/m2/ day IV, D1-4\]” NCT04378647 ↗ “Etoposide: 100 mg/(m2•d),ivgtt,D1-3;” NCT02526823 ↗ “Etoposide: 100mg/m2, IV, D1-D3, Q3W” NCT07357623 ↗ “cisplatin/carboplatin and etoposide” NCT06306560 ↗ “Etoposide: 100 mg/m² IV on Days 1-3” NCT07091305 ↗ “Estramustine, Etoposide, Exemestane” NCT02788201 ↗ “Etoposide 100 mg/m² IV on Days 1-3” NCT07358676 ↗ “Etoposide 50 mg/m2/day CI24h d1-d4” NCT01818908 ↗ “etoposide (50 mg/m2 day1-5, 29-33)” NCT01211002 ↗ “etoposide (100 mg/sqm on days 1-3)” NCT06418087 ↗ “etoposide (VP-16) IV over 4 hours” NCT00550992 ↗ “Etoposide: 100 mg/m2 i.v. day 1-3” NCT00791947 ↗ “Etoposide 100 mg/m² i.v. days 1-5” NCT00151255 ↗ “Daily oral Etoposide (50 mg/m2/d)” NCT01858571 ↗ “Etoposide 100 mg/m²/d i.v. (d1-3)” NCT02531841 ↗ “Etoposide: 100 mg/m2, ivgtt, d1-3” NCT06462105 ↗ “Etoposide 200mg/m2 Day 1 to Day 3” NCT01304849 ↗ “etoposide 100 mg/m2 i.v. d 15-17” NCT00517894 ↗ “etoposide (total dose 450 mg/m2)” NCT04499573 ↗ “etoposide 50mg/m2/d CIV days 1-4” NCT01914718 ↗ “etoposide 100 mg/m 2 days 1 - 3” NCT03154918 ↗ “etoposide 100mg/ m2,VD d2,d3,d4” NCT01933282 ↗ “etoposide, 100mg/m² IV day1\~3” NCT02445404 ↗ “Erlotinib Etoposide Everolimus” NCT02551718 ↗ “Etoposide, 100mg/m2, day 1\~3.” NCT06978153 ↗ “etoposide (100 mg/m2 per day)” PMID 31175001 ↗ Jun 2019 “Vepesid(R), VP-16 (etoposide)” NCT00602667 ↗ “etoposide: 100 mg/m2 days 1-3” NCT01576692 ↗ “Etoposide IV (100 mg/m²) day2” NCT00863460 ↗ “* Etoposide 60 mg/m2 Days 1-4” NCT00577512 ↗ “Etoposide 60mg/m2, ivg. d1-4.” NCT03105596 ↗ “etoposide, 200mg, p.o., d2-d4” NCT06069830 ↗ “etoposide(200mg/ m2.d, d3-d5)” NCT06933394 ↗ “Etoposide (VP-16) (Vepesid®)” NCT02128230 ↗ “Etoposide 100 mg/m2 on D2-4” NCT04066920 ↗ “etoposide 40 mg/m2 days 1-4” NCT00670631 ↗ “Etoposide 100 mg/m2 IV D1-3” NCT05348213 ↗ “Etoposide 40 mg/m2, D1-4” NCT01300156 ↗ “etoposide IV on days 1-3” NCT00433433 ↗ “Etoposide 100 mg/m2 day1” NCT05164978 ↗ “etoposide 40 mg/m2 D1-4” NCT05244642 ↗ “Etoposide 50mg/m2 ,d1-4” NCT04134247 ↗ “etoposide 75 mg/m2 day1” NCT05775705 ↗ “Etoposide 0.1 g,qd,d1-5” NCT06328179 ↗ “etoposide 100 mg/m2 d1” NCT06504030 ↗ “Etoposide 40mg/m2 D1-4” NCT02431403 ↗ “etoposide(100mg/m2)D1” NCT03841136 ↗ “etoposide + platinum” NCT00391586 ↗ “Etoposide (VdPesid)” NCT00856830 ↗ “Etoposide 50mg/ m2” NCT05097443 ↗ “Drug: Etoposide” NCT03206671 ↗ “Drug: etoposide” NCT03533790 ↗ “EPI:etoposide” NCT03201471 ↗ “Etoposide” NCT02665065 ↗ “Etoposide” NCT03793478 ↗ “Etoposide” NCT06667167 ↗ “Etoposide” NCT01468740 ↗ “Etoposide” NCT03837873 ↗ “Etoposide” NCT00592111 ↗ “Etoposide” NCT00734877 ↗ “Etoposide” NCT01873807 ↗ “Etoposide” NCT01703910 ↗ |
| Known as | Ad2/HIF-1α/VP16 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00117650 ↗ |
| Known as | EPI | “EPI:etoposide” NCT03201471 ↗ |
| Known as | Eto | “gemcitabine (Gem) with vinorelbine (Vin), etoposide (Eto), cisplatin (Cis), or carboplatin (Car).” PMID 22031232 ↗ Jan 2012 |
| Known as | Etopophos | “Etoposide phosphate (Etopophos; Bristol-Myers Squibb Company, Princeton, NJ) is a water-soluble prodrug of etoposide” NCT06356883 ↗ |
| Known as | Etoposid | ClinicalTrials.gov intervention name — accepted as the source's own label NCT07699237 ↗ |
| Known as | Etoposide (E) | “Etoposide (E)” NCT01858922 ↗ |
| Known as | Etoposide (VdPesid) | “Etoposide (VdPesid)” NCT00856830 ↗ |
| Known as | Etoposide (VP-16) (Vepesid) | “Etoposide (VP-16) (Vepesid®)” NCT02128230 ↗ |
| Known as | Etoposide (VP-16; Vepesid(R) brand only) | “Etoposide (VP-16; Vepesid(R) brand only)” NCT00005797 ↗ |
| Known as | Etoposide - VP-16, Etopophos, Toposar, VePesid | “Etoposide - VP-16, Etopophos, Toposar, VePesid” NCT00613223 ↗ |
| Known as | Etoposide 20 mg/ml Concentrate for solution for infusion | “Etoposide 20 mg/ml Concentrate for solution for infusion” NCT06418087 ↗ |
| Known as | Etoposide Capsule | “Etoposide Capsule” NCT03707847 ↗ |
| Known as | Etoposide Capsules | “Etoposide Capsules is given orally at a dosage of 50mg or 25mg daily, day 1 to 14 of a 21-day cycle” NCT07141264 ↗1“Apatinib Combined With Temozolomide and Etoposide Capsules” NCT04501718 ↗ |
| Known as | Etoposide Injection | “etoposide injection interferes with the division process of cancer cells to inhibit their growth and spread” NCT06897579 ↗2“Etoposide injection (E): 100mg/m2, ivgtt, d1,d2,d3,Q3W” NCT06614621 ↗ “Drug: Etoposide Injection” NCT06786312 ↗ |
| Known as | etoposide phosphate | “Patients receive etoposide phosphate IV continuously on days 1-4, high-dose cytarabine IV over 2 hours every 12 hours for a total of 8 doses on days 1-4” NCT01256398 ↗43“Patients receive N5 chemotherapy comprising cisplatin IV continuously over 96 hours and etoposide phosphate IV continuously over 96 hours on days 1-4” NCT00410631 ↗ “etoposide phosphate IV over 2 hours” NCT00417053 ↗ “etoposide phosphate (etoposide)” NCT03113500 ↗ |
| Known as | Etoposide-Etopophos-Toposar-VePesid-VP-16 | “Etoposide-Etopophos-Toposar-VePesid-VP-16” NCT00612430 ↗ |
| Known as | Etoposide: Eposin, Neoposid, Vepesid, Etopophos | “Etoposide: Eposin, Neoposid, Vepesid, Etopophos” NCT01563601 ↗ |
| Known as | Etoposide: VP-16, VePesid, VP-16-213, EPEG, epipodophyllotoxin, NSC #141540 | “Etoposide: VP-16, VePesid, VP-16-213, EPEG, epipodophyllotoxin, NSC #141540” NCT00958022 ↗ |
| Known as | Lastet | “Lastet, dosing regimen: 50 mg/day orally, every 28 days in a cycle, two weeks of continuous oral administration, two weeks off.” NCT06463171 ↗ |
| Known as | NSC-141540 | “CVP: Cyclophosphamide, CTX, NSC-26271; Etoposide, VP-16, NSC-141540; Cisplatin, CDDP, NSC-119875.” NCT00002488 ↗8“Etoposide, VP-16, NSC-141540.” NCT00002588 ↗ “Etoposide, VP-16, NSC-141540” NCT00002567 ↗ “Etoposide, VP-16, NSC-141540” NCT00002471 ↗ “Etoposide, VP-16, NSC-141540” NCT00002510 ↗ “VP-16 Etoposide, NSC-141540” NCT00002565 ↗ “VP-16 Etoposide, NSC-141540” NCT00001339 ↗ “VP-16 Etoposide, NSC-141540” NCT00002691 ↗ “VP-16 Etoposide, NSC-141540” NCT00002557 ↗ |
| Known as | NSC-301739 | “NSC-301739 VP-16 Etoposide” NCT00002688 ↗ |
| Known as | VePesid | “Etoposide (VePesid)” NCT00514540 ↗ |
| Known as | vepesid (etoposide) | “vepesid (etoposide)” NCT01756989 ↗ |
| Known as | Vepesid(R), VP-16 (etoposide) | “Vepesid(R), VP-16 (etoposide)” NCT00602667 ↗ |
| Known as | Vepeside | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02104986 ↗ |
| Known as | VP 16,213 | “mitoxantrone and etoposide (VP 16,213) to overcome resistance to chemotherapy” NCT00002688 ↗ |
| Known as | VP-16 | “Phase II Study of IV Busulfan Combined With 12 cGy of Fractionated Total Body Irradiation (FTBI) and Etoposide (VP-16) as a Preparative Regimen for Allogeneic Bone Marrow...” NCT00534430 ↗93“Tucatinib in Combination With Oral Etoposide (VP16) - Trastuzumab in Patients With Metastatic HER2+ Breast Cancer After Progression Under Tucatinib-Capecitabine-Trastuzumab or...” NCT05955170 ↗ “Those without an MSD (n = 22) underwent mobilization with Cy, RTX, and filgrastim and received a conditioning regimen of either CBV (Cy, carmustine, Etoposide [VP16]) or total...” PMID 21073974 ↗ Nov 2010 “Topo II inhibitor Etoposide (VP-16) can reduce cell survival, enhance DNA damage, and delay resistance in Osimertinib-resistant cells, suggesting a potential combination...” NCT06436144 ↗ “Explore the relationship between drug target topoisomerase II gene single nucleotide polymorphisms and Etoposide (VP-16) therapeutic-effects in patients with small cell lung cancer” NCT01064466 ↗ “Patients were randomly assigned to receive either high-dose etoposide (VP16; 1.2 g/m2) or high-dose cyclophosphamide (CTX; 3.0 g/m2) before mobilization.” PMID 41927700 ↗ Apr 2026 “Before initiating ThisCART19A infusion, subjects will be administered lymphodepletion chemotherapy composed of fludarabine、cyclophosphamide and VP-16.” NCT05679687 ↗ “The recommended chemotherapy is based on the current reference combination of platinum (cisplatin or carboplatin) and etoposide (VP16).” NCT04268121 ↗ “regimen 1: CTX 1.2mg/m2 D1 + ADM 50mg / m2 D1 + VCR 1.4mg/m2 D1 and regimen 2: IFO 1.5g/m2 D1-5 + VP-16 100mg / m2 D1-5, IV drip” NCT04589754 ↗ “Autologous bone marrow (ABM) is harvested and two-thirds of the ABM is treated in vitro with etoposide (VP-16).” NCT00002461 ↗ “etoposide (VP-16) IV over 1 hour (beginning after CTX infusion) on days 1-5 of weeks 3, 9, 15, and 21” NCT00002611 ↗ “CVP: Cyclophosphamide, CTX, NSC-26271; Etoposide, VP-16, NSC-141540; Cisplatin, CDDP, NSC-119875.” NCT00002488 ↗ “Cladribine combined with cytarabine and VP16 sequential with Fludarabine combined with busulifan” NCT03882203 ↗ “Etoposide (VP-16) is administered after carboplatin by 30 minute IV infusions” NCT00003158 ↗ “Esc.BEACOPP Bleomicine10 mg/m2/ev/die 8° VP-16 200 mg/m2/ev/die1°- 3°” NCT00795613 ↗ “alternating prolonged exposure to topotecan and etoposide (VP-16)” NCT00250094 ↗ “patients receive etoposide (VP-16) IV over 2 hours on days 1-3” NCT00040872 ↗ “Etoposide (VP-16) 200 mg/m2/day on Days 2-4 (total of 3 days)” NCT00187070 ↗ “Cyclophosphamide, Etoposide (VP16) and TBI (Pediatric only)” NCT00281879 ↗ “VIA: VP-16 (Etoposide),Ifosfamide,Mesna, Cytarabine (ara-C)” NCT01083342 ↗ “scheme 2: IFO 1.5g/m2 D1-5 + vp-16 90mg / m2 D1-5, IV drip” NCT04589741 ↗ “apatinib 250mg qd continuously combined with VP-16 50mg qd” NCT03805399 ↗ “regimen2: IFO 1.5g/m2 D1-5 + VP-16 90mg/m2 D1-5, IV drip” NCT04589741 ↗ “Etoposide (VP-16) 100 mg/m2 twice a day (Days -5 to -2)” NCT00329030 ↗ “etoposide (VP-16) every 12 hours on days 3-5 (5 doses)” NCT01117441 ↗ “oral etoposide (VP-16) on days 15-19, 43-47, and 71-75” NCT00003815 ↗ “high-dose etoposide (VP-16) IV over 4 hours on day -3.” NCT00002514 ↗ “Etoposide (VP-16) is given over 1-2 hours on day 2.” NCT00002788 ↗ “etoposide (VP-16) IV over 1 hour on days 2-4” NCT00017368 ↗ “Etoposide (VP 16)100 mg/m2 i.v. over 2 hours” NCT01385891 ↗ “etoposide (VP-16) IV over 1 hour on days 6-8” NCT00002517 ↗ “etoposide (VP-16) IV over 1 hour on days 3-5” NCT00003728 ↗ “VP16 (etoposide) 300 mg/m2 IV over 2 hours” NCT00187005 ↗ “EP(VP-16 100mg/m2 d1-3;DDP 60-75mg/m2 d1)” NCT01737216 ↗ “Etoposide (VP16) 100 mg/m² IV in 1 hour.” NCT05049473 ↗ “etoposide (VP-16) IV over 30-60 minutes” NCT00002596 ↗ “VP-16 (Etoposide) 40 mg/m2 IV Days 1-4” NCT00109928 ↗ “etoposide (VP-16) IV over 2 hours once” NCT00006455 ↗ “Drug: VP-16 Lympho-conditioning Agent” NCT06027853 ↗ “VP16 225 mg/m2/dose days 22, 25, 29” NCT00187057 ↗ “etoposide (VP-16) IV over 4 hours” NCT00550992 ↗ “VP-16 every 12 hours on dd 2-5” NCT01516593 ↗ “etoposide (VP-16) 100 mg/m2/d” PMID 7595741 ↗ Nov 1995 “Etoposide, VP-16, NSC-141540.” NCT00002588 ↗ “weekly oral etoposide (VP-16)” NCT00000660 ↗ “Vp16 200 mg/m2 ,ivgtt,d-5- -2” NCT05814718 ↗ “Etoposide, VP-16, NSC-141540” NCT00002567 ↗ “Etoposide, VP-16, NSC-141540” NCT00002471 ↗ “Etoposide, VP-16, NSC-141540” NCT00002510 ↗ “VP-16 Etoposide, NSC-141540” NCT00002565 ↗ “VP-16 Etoposide, NSC-141540” NCT00002557 ↗ “VP-16 Etoposide, NSC-141540” NCT00002549 ↗ “VP-16 Etoposide, NSC-141540” NCT00002757 ↗ “VP-16 Etoposide, NSC-141540” NCT00002691 ↗ “VP-16(100mg/m2,days 1 to 5)” NCT06084819 ↗ “Drug: Etoposide (VP-16)” NCT03623087 ↗ “Etoposide (VP-16)” NCT03733327 ↗ “Etoposide (VP-16)” NCT03385096 ↗ “Etoposide (VP-16)” NCT00165139 ↗ “Etoposide (VP-16)” NCT03229616 ↗ “VP-16 Etoposide” NCT00002674 ↗ |
| Action | Activate | “encoding constitutively active HIF-1α” PMID 21947297 ↗ Sep 2011 |
| Modality | Small molecule | “Etoposide is a semi-synthetic podophyllotoxin derivative.” NCT03072771 ↗ |
| Route | Oral | “weekly oral etoposide (VP-16)” NCT00000660 ↗ |
| Target | HIF1A | “encoding constitutively active HIF-1α” PMID 21947297 ↗ Sep 2011 |