drugset / Trial / NCT01416961

Integration of Neutron Therapy in the Treatment Plan for Stage III Non-Small Cell Lung Cancer (NSCLC)

NCT01416961

NaSingle-groupOpen-labelTreatment

Summary

This study is needed to assess the feasibility of integrating this therapy with current treatment regimens. If this study shows success a formal phase II test study to conduct feasibility will be the next step. The first dose level chosen for this study is 66Gy of radiation to the tumor between LET and standard photon therapy. This dose is the current standard of care for stage III . If this dose is found to be feasible then the dose of LET will escalate to the total dose of 74Gy.

Timeline

Start
2011-08
Primary completion
2011-12
Completion
2011-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified 50 mg/m2
Subject Cisplatin Other / unclassified 75 mg/m2
Subject Etoposide Small molecule 50 mg/m2
Subject Pemetrexed Small molecule 500 mg/m2

Indications