drugset / Trial / NCT00537511

A Phase I/II Study to Determine the Maximum Tolerated Dose (MTD) and Safety of CC-4047 (Pomalidomide) Administered in Conjunction With Cisplatin and Etoposide

NCT00537511

Phase 1/2 Terminated 22 enrolled Celgene Corporation
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine the maximum tolerated dose and safety of CC-4047 (pomalidomide) given in combination with cisplatin and etoposide in patients with extensive disease small cell lung cancer.

Timeline

Start
2008-02-01
Primary completion
2010-11-01
Completion
2010-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified 25 mg/m2 Intravenous
Subject Etoposide Small molecule 100 mg/m2 Intravenous
Subject Pomalidomide Other / unclassified 1 mg Oral
Subject Pomalidomide Other / unclassified 3 mg Oral
Subject Pomalidomide Other / unclassified 4 mg Oral
Subject Pomalidomide Other / unclassified 5 mg Oral

Indications