drugset / Trial / NCT05384821
Metronomic Chemotherapy in Wilms Tumor (MetroWilms-1906)
NaSingle-groupOpen-labelTreatment
Summary
This is a multicenter, interventional, non-randomized study among patients with a relapsed or refractory Wilms tumor. The study will aim to assess efficacy of metronomic chemotherapy, in terms of disease control after two cycles of metronomic chemotherapy.
Timeline
- Start
- 2022-09-14
- Primary completion
- 2028-05
- Completion
- 2028-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cis-Retinoic acid | Unknown | — | Oral |
| Subject | Etoposide | Small molecule | — | Oral |
| Subject | Irinotecan | Small molecule | — | Oral |
| Subject | Temozolomide | Small molecule | — | Oral |
| Subject | Vincristine | Small molecule | — | Intravenous |