drugset / Trial / NCT03509012

Immunotherapy in Combination With Chemoradiation in Patients With Advanced Solid Tumors

NCT03509012

Phase 1 Completed 105 enrolled AstraZeneca
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is an open-label, multicenter, phase I study to evaluate the safety and tolerability of durvalumab ± tremelimumab in combination with chemoradiation in patients with advanced solid tumors

Timeline

Start
2018-05-02
Primary completion
2020-12-31
Completion
2025-01-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule
Subject Cisplatin Other / unclassified
Subject Durvalumab Monoclonal antibody Intravenous
Subject Etoposide Small molecule
Subject Paclitaxel Small molecule
Subject Pemetrexed Small molecule
Subject Tremelimumab Monoclonal antibody