Paclitaxel
Small molecule targets TLR4 via activation
Regulatory milestones approvals, filings & regulatory actions · 14 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | PACLITAXEL | — | 2023-11-21 | fda.gov ↗ |
| Label expansions (4) | US (FDA) | ABRAXANE | — | 2007-02-15 – 2019-12-06 | fda.gov ↗ |
| Label expansions (7) | US (FDA) | TAXOL | — | 1994-04-13 – 2000-06-20 | fda.gov ↗ |
| Approved | EU (EMA) | Paxene | — | 1999-07-19 | europa.eu ↗ |
| Approved | US (FDA) | TAXOL | — | 1992-12-29 | fda.gov ↗ |
Trials 2,049 · started per year
Press releases naming this drug 137 releases
Evidence & citations 76 cited values
Every value below carries the sentence it was read from. 3,705 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | paclitaxel | “Option 1: Docetaxel and carboplatin once every 3 weeks for 6 cycles; Option 2: Doxorubicin plus cyclophosphamide once every 3 weeks for 4 cycles, followed by a taxane...” NCT05415215 ↗3637“Patients with stage IV non-small cell lung cancer and stable disease after two cycles of cisplatin (P) and gemcitabine (G) (P day1 (d(1)): 75 mg/m(2), G: 1250 mg/m(2) d(1) and...” PMID 19155999 ↗ Mar 2009 “Camrelizumab 200 mg (Day 1) intravenous infusion (IV) and Paclitaxel Albumin - bound 125 mg/m² (Day 1, Day 8) IV and Carboplatin AUC 4 (Day 1) IV, with a 21-day cycle for 2...” NCT07432087 ↗ “The SAVAL trial is a prospective, multicenter, randomized trial of patients with CLTI and infrapopliteal artery lesions with total lesion length ⩽ 140 mm, stenosis ⩾ 70%, and...” PMID 37844137 ↗ Oct 2023 “We performed a prospective, randomized, phase III, intergroup trial to compare carboplatin plus paclitaxel (TC; area under the curve [AUC] 5 and 175 mg/m(2), respectively) with...” PMID 20733132 ↗ Aug 2010 “Any of the following single-agent chemotherapy may be given at the discretion of the investigator, with a cycle length not to exceed four weeks: Capecitabine, Vinorelbine,...” NCT01156753 ↗ “Squamous cell carcinoma: Paclitaxel (175mg/m²) or Docetaxel (60-75 mg/m²) or Nab-paclitaxel (260mg/m²) plus Carboplatin (AUC=5)/Cisplatin (75 mg/m²) (to be determined by...” NCT07608159 ↗ “Acceptable histology-specific PDC regimens include carboplatin plus paclitaxel or nab-paclitaxel (any histology), carboplatin/cisplatin plus pemetrexed (nonsquamous),...” NCT06865339 ↗ “Treatment with LV5FU2 (5-FU, Calcium Levofolinate) - paclitaxel, regular tumor evaluation, best supportive care Other authorized treatment : usual paclitaxel pre-treatment...” NCT03301454 ↗ “platinum-based doublet chemotherapy (carboplatin [area under the curve ≤700 mg] plus pemetrexed [500 mg/m2 intravenous infusion every 3 weeks] or carboplatin [on day 1; area...” PMID 39486424 ↗ Oct 2024 “All patients will receive a one-cycle lead-in of carboplatin (with or without) paclitaxel followed by three cycles of carboplatin, paclitaxel, and pembrolizumab prior to...” NCT05952453 ↗ |
| Known as | ABI-007 | “ABI-007 \[Abraxane™ (paclitaxel protein-bound particles for injectable suspension) (albumin-bound)\] is the first in its class of biologically interactive albumin-bound forms...” NCT00284752 ↗7“Patients receive oral lapatinib on days 1, 2, 8, 9, 15, and 16 and paclitaxel (albumin-stabilized nanoparticle formulation) (ABI-007; Abraxane™) IV over 30 minutes on days 3,...” NCT00313599 ↗ “The 130 nm albumin bound paclitaxel (nab-paclitaxel, ABI-007) delivers more paclitaxel to tumor than conventional paclitaxel without cremophor related toxicities.” PMID 24318901 ↗ Dec 2013 “ABI-007 is an albumin-bound formulation of paclitaxel that has demonstrated single-agent activity against metastatic melanoma.” PMID 21472717 ↗ Nov 2010 “ABI-007 (brand name Abraxane™) is a form of the chemotherapy drug called paclitaxel.” NCT00585689 ↗ “paclitaxel albumin-stabilized nanoparticle formulation (ABI-007; Abraxane\^®)” NCT00404404 ↗ “paclitaxel (albumin-stabilized Nanoparticle formulation) (ABI-007)” NCT00077246 ↗ “ABI-007 (Abraxane, Nanoparticle Albumin-Bound Paclitaxel)” NCT00397761 ↗ |
| Known as | Abraxane | “Abraxane (nab-pac, Celgene) is a novel 130 nm, albumin-bound (nab) nanoparticle formulation of paclitaxel which has noteworthy single-agent activity and a favourable toxicity...” NCT03304210 ↗17“Abraxane is a new agent in pancreatic cancer. This albumin-bound nanoparticle form of paclitaxel increases tumor accumulation of paclitaxel though binding of albumin to SPARC...” NCT01744353 ↗ “ABI-007 \[Abraxane™ (paclitaxel protein-bound particles for injectable suspension) (albumin-bound)\] is the first in its class of biologically interactive albumin-bound forms...” NCT00284752 ↗ “neoadjuvant treatment with nanoparticle albumin bound paclitaxel (Abraxane) every week for 12 weeks followed by 5-FU, epirubicin, and cyclophosphamide (FEC) every 3 weeks for 4 cycles” NCT00110695 ↗ “Investigational" means that the Albumin bound paclitaxel (Abraxane) is still being studied and that research doctors are trying to find out more about it.” NCT01698710 ↗ “Abraxane, an albumin-bound formulation of paclitaxel has shown significant single-agent activity in breast cancer and in head and neck cancer.” NCT00319839 ↗ “Abraxane® (nanoparticle albumin-bound paclitaxel) compared to standard paclitaxel improves efficacy and tolerability.” NCT01207102 ↗ “The 130-nm albumin-bound formulation of paclitaxel ([Abraxane, ABX ];Celgene,Summit,NJ) is a promising new agent” NCT01735409 ↗ “ABI-007 (brand name Abraxane™) is a form of the chemotherapy drug called paclitaxel.” NCT00585689 ↗ “paclitaxel albumin-stabilized nanoparticle formulation (ABI-007; Abraxane\^®)” NCT00404404 ↗ “paclitaxel protein-bound particles (Abraxane) 260 mg/m\^2 IV every 3 weeks” NCT00281697 ↗ |
| Known as | Abraxane (albumin-bound paclitaxel) | “Abraxane (albumin-bound paclitaxel)” NCT01667211 ↗ |
| Known as | Abraxane(Albumin-bound paclitaxel,nab-P) | “Abraxane(Albumin-bound paclitaxel,nab-P)” NCT01236716 ↗ |
| Known as | ABX | “The 130-nm albumin-bound formulation of paclitaxel ([Abraxane, ABX ];Celgene,Summit,NJ) is a promising new agent” NCT01735409 ↗1“Albumin-Bound Paclitaxel(ABX) intravenous drip” NCT06330337 ↗ |
| Known as | Albumin bound (nab)-paclitaxel | “Albumin bound (nab)-paclitaxel combined with carboplatin followed by epirubicin and cyclophosphamide” NCT04067102 ↗ |
| Known as | Albumin paclitaxel | “Regorafenib combined with Toripalimab and Albumin paclitaxel as the third line treatment for patients with advanced pancreatic cancer” NCT07040228 ↗1“Albumin paclitaxel: 100mg per bottle, 125mg/m2 IV Days 1, 8, cycled every 21 days” NCT05244993 ↗ |
| Known as | albumin-binding paclitaxel | “All enrolled patients received carrilizumab combined with albumin-binding paclitaxel.” NCT05886140 ↗ |
| Known as | Albumin-bound paclitaxel | “BACKGROUND: For patients with untreated pancreatic ductal adenocarcinoma (PDAC), chemotherapy before surgery ("neoadjuvant therapy") has shown benefit in reducing recurrence...” PMID 42268676 ↗ Jun 202621“The purpose of this study was to investigate the use of systemic intracoronary administration of albumin-bound paclitaxel, ABI-007, for the prevention and reduction of...” NCT00124943 ↗ “Albumin-bound paclitaxel is a novel, solvent-free, albumin-bound, 130 nanometer particle form of paclitaxel designed to avoid the problems associated with solvents used in...” NCT00398086 ↗ “this study aims to observe and explore the efficacy and safety of the combination of albumin-bound paclitaxel (keaili) and liposomal doxorubicin (duomeisu) in the treatment of...” NCT04859465 ↗ “Albumin-bound paclitaxel(nab-paclitaxel) has been used to treat a variety of malignancies such as non-small cell lung cancer, pancreatic cancer, breast cancer, melanoma,...” NCT04077983 ↗ “Paclitaxel Powder For Injectable Suspension Nanoparticle, Albumin-bound Paclitaxel is an albumin-stabilized nanoparticle formulation of the natural taxane paclitaxel with...” NCT06783140 ↗ “Efficacy and safety of albumin-bound paclitaxel combined with simvastatin in the second-line treatment of small cell lung cancer: a phase II randomized controlled trial.” PMID 41937137 ↗ Apr 2026 “Albumin-bound paclitaxel is a novel, solvent-free, albumin-bound nanoparticle form of paclitaxel designed to avoid problems associated with solvents used in Taxol.” NCT01667211 ↗ “A Phase Ib/II Clinical Study of Regorafenib Combined With Toripalimab and Albumin-bound Paclitaxel for the Third-line Treatment of Advanced Pancreatic Cancer” NCT07040228 ↗ “Investigational" means that the Albumin bound paclitaxel (Abraxane) is still being studied and that research doctors are trying to find out more about it.” NCT01698710 ↗ “Patients were treated with albumin-bound paclitaxel 100 mg/m2 and carboplatin at area under the curve (AUC) = 2 on days 1, 8, and 15 of a 28-day cycle.” PMID 20705560 ↗ Aug 2010 |
| Known as | Anzatax | “Anzatax” NCT06323460 ↗ |
| Known as | Asotax | “Asotax” NCT07281417 ↗ |
| Known as | DHP107 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03326102 ↗ |
| Known as | EndoTAG-1 | “This is a prospective, multicenter, open-label, randomized, and controlled trial to test the superiority of EndoTAG®-1 in combination with paclitaxel and gemcitabine versus...” NCT03002103 ↗ |
| Known as | Genexol | “D1, D8 Genexol (Paclitaxel) 80 mg/m2 + D5W 500mL MIV over 3hrs” NCT00816634 ↗ |
| Known as | Genexol-PM | “This is a phase I trial to determine the maximum tolerated dose and recommended phase II dose of the combination therapy with Genexol®-PM and Carboplatin and to evaluate the...” NCT00877253 ↗10“To evaluate the efficacy and safety Genexol-PM(CrEL-free polymeric micelle formulated paclitaxel)and gemcitabine in untreated metastatic NSCLC patients” NCT01770795 ↗ “Genexol-PM is a novel Cremophor® EL (CrEL)-free polymeric micelle formulation of paclitaxel.” PMID 22012004 ↗ Oct 2011 “Paclitaxel loaded polymeric micelle (Genexol-PM®)” NCT01023347 ↗ |
| Known as | keaili | “this study aims to observe and explore the efficacy and safety of the combination of albumin-bound paclitaxel (keaili) and liposomal doxorubicin (duomeisu) in the treatment of...” NCT04859465 ↗ |
| Known as | Kealil | “albumin-bound paclitaxel injection (Kealil)” NCT06078670 ↗ |
| Known as | LDE-paclitaxel | “Paclitaxel carried by a lipid nanoparticle (LDE-Paclitaxel)” NCT04148833 ↗ |
| Known as | LEP-ETU | “LEP-ETU is a new formulation of the anti-cancer agent paclitaxel for injection or Taxol (paclitaxel and Cremophor EL).” NCT00080418 ↗1“Liposome Entrapped Paclitaxel Easy to Use (LEP-ETU) is being compared to Taxol®” NCT00100139 ↗ |
| Known as | Lipid Complexed Paclitaxel | “Weekly Infusions of Gemcitabine and Twice Weekly Administration of Lipid Complexed Paclitaxel (EndoTAG-1)” NCT00377936 ↗ |
| Known as | Micellar Paclitaxel | “using intravenous Micellar Paclitaxel (75 mg/m(2) every 4 weeks) for six months.” NCT00006276 ↗ |
| Known as | Nab-P | “At baseline, patients receive the Nab-P+HP regimen (albumin-bound paclitaxel plus trastuzumab and pertuzumab).” NCT07239271 ↗ |
| Known as | nab-pac | “Abraxane (nab-pac, Celgene) is a novel 130 nm, albumin-bound (nab) nanoparticle formulation of paclitaxel which has noteworthy single-agent activity and a favourable toxicity...” NCT03304210 ↗ |
| Known as | nab-paclitaxel | “This phase II trail will evaluate the efficacy and safety of combining gemcitabine hydrochloride, cisplatin, nab-paclitaxel (paclitaxel albumin-stabilized nanoparticle...” NCT06591650 ↗14“This phase I/II trial studies the side effects, maximum tolerated dose, and effectiveness of paclitaxel albumin-stabilized nanoparticle formulation (nab-paclitaxel) in treating...” NCT01555853 ↗ “Albumin-bound paclitaxel(nab-paclitaxel) has been used to treat a variety of malignancies such as non-small cell lung cancer, pancreatic cancer, breast cancer, melanoma,...” NCT04077983 ↗ “The combination of nab-paclitaxel (now called paclitaxel protein bound) and gemcitabine had a high response and survival in the phase I and II study in advanced pancreatic cancer.” NCT03138720 ↗ “In this phase II trial, carboplatin with nanoparticle albumin-bound (nab)-paclitaxel as first-line therapy for advanced non-small-cell lung cancer (NSCLC) was evaluated.” PMID 26123189 ↗ May 2015 “The 130 nm albumin bound paclitaxel (nab-paclitaxel, ABI-007) delivers more paclitaxel to tumor than conventional paclitaxel without cremophor related toxicities.” PMID 24318901 ↗ Dec 2013 “Nab-paclitaxel is a nanoparticle albumin-bound paclitaxel that showed anti-tumor activity as well as synergistic effect in combination with gemcitabine.” NCT03502343 ↗ “They were given serplulimab 4.5 mg/kg for up to 2 years (35 dosing cycles) plus nab-paclitaxel 260 mg/m2 for up to six cycles once every 3 weeks.” PMID 37153587 ↗ Apr 2023 “A phase II trial of neoadjuvant nab-paclitaxel, carboplatin, and gemcitabine (ACaG) in patients with locally advanced carcinoma of the bladder.” PMID 23706253 ↗ May 2013 “This study aimed to investigate the efficacy and safety of nab-paclitaxel combined with simvastatin as second-line treatment for SCLC patients.” PMID 41937137 ↗ Apr 2026 “Neoadjuvant anthracycline followed by toripalimab combined with nab-paclitaxel” NCT04418154 ↗ |
| Known as | nab-PTX | “We aimed to study the tolerability, safety, pharmacokinetics, and tumour response of nanoparticle albumin bound paclitaxel (NAB-PTX) during PIPAC in a Phase I study.” PMID 35843174 ↗ Jul 20221“Participants received a single dose of albumin-bound paclitaxel (nab-PTX) 270mg/m2/d, administered intravenously (IV) on Day 1” NCT04581265 ↗ |
| Known as | NanoPac | “NanoPac is very small (submicron) particles of the chemotherapy drug, paclitaxel, which is administered intravenously in a number of types of cancer.” NCT04314895 ↗1“NanoPac® (Sterile Nanoparticulate Paclitaxel) for intracystic injection via endoscopic ultrasound-guided injection (EUS-FNI)” NCT03188991 ↗ |
| Known as | Nanoparticle Paclitaxel | “Drug: Nanoparticle Paclitaxel” NCT00124943 ↗ |
| Known as | nanoparticlealbumin-bound paclitaxel | “PURPOSE: This multicenter phase II trial evaluated the efficacy and safety of weekly nanoparticle albumin-bound paclitaxel with carboplatin and weekly trastuzumab as first-line...” PMID 20705560 ↗ Aug 20105“The objective of this single-arm phase II trial was to evaluate the benefit of neoadjuvant chemotherapy with nanoparticle albumin-bound paclitaxel plus 5-fluorouracil in...” NCT02033538 ↗ “Nanoparticle albumin-bound paclitaxel is given at 125 mg/m2 intravenously on day 1 of each 14 day cycle or day 1 and 8 of 21 day cycle.” NCT03636308 ↗ “Take nanoparticlealbumin-bound paclitaxel (125mg/m2, d1) per week for 3 weeks as one cycle for 4 cycles with Toripalimab” NCT04418154 ↗ “Nanoparticle albumin-bound paclitaxel, administered via intracoronary catheter.” NCT00124943 ↗ “nanoparticle albumin-bound paclitaxel (nab (®)-paclitaxel)” PMID 27411683 ↗ Jul 2016 |
| Known as | Nanoxel | “Nanoxel (Paclitaxel Nanoparticle formulation )” NCT00915369 ↗ |
| Known as | NSC # 673089 | “A Dose-Escalating Phase I Study With an Expanded Cohort to Assess the Feasibility of Intraperitoneal Carboplatin (NSC #214240) and Intravenous Paclitaxel (NSC # 673089) and...” NCT00079430 ↗4“Evaluation of Paclitaxel (Taxol, NSC #673089), Carboplatin (Paraplatin, NSC #241240), and BSI-201 (NSC #746045, IND #71,677) in the Treatment of Advanced, Persistent, or...” NCT00687687 ↗ “A Limited Access Phase II Trial of Weekly Topotecan (NSC #609699), Paclitaxel (NSC #673089), and Cisplatin (NSC #119875) in the Treatment of Advanced, Persistent, or Recurrent...” NCT00276796 ↗ “OUTLINE: Single-Agent Chemotherapy. Paclitaxel, TAX, NSC-673089.” NCT00002562 ↗ “Paclitaxel (Taxol, NSC # 673089)” NCT00112489 ↗ |
| Known as | NSC-125973 | “OUTLINE: Single-Agent Chemotherapy. Paclitaxel (Bristol-Myers), Taxol, TAX, NSC-125973.” NCT00002632 ↗3“Paclitaxel, TAX, NSC-125973; Cisplatin, CDDP, NSC-119875” NCT00001499 ↗ “plus Paclitaxel (Bristol-Myers), Taxol, TAX, NSC-125973.” NCT00001442 ↗ “Paclitaxel (Bristol-Myers), Taxol, NSC-125973.” NCT00002568 ↗ |
| Known as | oPac | “oral paclitaxel plus E (oPac + E)” PMID 35858154 ↗ Jul 2022 |
| Known as | Oral Paclitaxel Solution | “Oral Paclitaxel Solution: 200 mg/m² administered on a 21-day cycle, with oral doses given on Day 1 and Day 8 of each cycle, taken twice daily (morning and evening).” NCT07599163 ↗ |
| Known as | PAB | “This study aimed to compare SYHX2011 and paclitaxel for injection (albumin-bound) (PAB) in patients with breast cancer.” PMID 42368972 ↗ Jun 2026 |
| Known as | PAC | “with the EGFR signaling inhibitor gefitinib (GEF) combined with weekly intravenous paclitaxel (PAC) and radiation therapy (RT).” PMID 19879702 ↗ Oct 20092“ipatasertib (ipat) in combination with atezolizumab (atezo) and paclitaxel (pac) or nab-paclitaxel” NCT03800836 ↗ “paclitaxel (PAC)” NCT07546812 ↗ |
| Known as | Paclimer | “A phase I trial of intraperitoneal sustained-release paclitaxel microspheres (Paclimer) in recurrent ovarian cancer: a Gynecologic Oncology Group study.” PMID 16626792 ↗ Apr 2006 |
| Known as | Paclitaxcel | “Neoadjuvant therapy with Paclitaxcel of 260mg/m2, iv, qd, on day 1, 22” NCT04473716 ↗ |
| Known as | paclitaxel (albumin-bound) | “Compare the effectiveness and safety of paclitaxel (albumin-bound) combined with radiotherapy and cisplatin combined with radiotherapy in the treatment of early nasopharyngeal...” NCT04766359 ↗5“All patients enrolled in the study will accept Paclitaxel (Albumin Bound),Bleomycin combined with Cisplatin or Carboplatin as their firstline chemotherapy” NCT03830385 ↗ “Paclitaxel (albumin-bound) 130 mg/m2, i.v., d1, 8; Carboplatin AUC 5, i.v. d1; repeat every 21days, 6 cycles.” NCT04661696 ↗ “Paclitaxel (albumin bound), intravenously, over 30 min on day 1, day 8 and day 15 of every 28-day cycle” NCT05047991 ↗ “Paclitaxel (albumin-bound)” NCT07392346 ↗ “Paclitaxel (albumin-bound)” NCT04443036 ↗ |
| Known as | Paclitaxel (Taxol, Abraxane) | “Paclitaxel (Taxol, Abraxane)” NCT00659269 ↗ |
| Known as | paclitaxel albumin-stabilized nanoparticle formulation | “To determine the maximum tolerated dose and recommended phase II dose of dovitinib (dovitinib lactate) when administered concurrently with gemcitabine (gemcitabine...” NCT02048943 ↗2“nab-paclitaxel (paclitaxel albumin-stabilized nanoparticle formulation)” NCT02194829 ↗ “Drug: paclitaxel albumin-stabilized nanoparticle formulation” NCT00662129 ↗ |
| Known as | Paclitaxel for Injection | “Paclitaxel for Injection” NCT07229586 ↗ |
| Known as | Paclitaxel for injection (albumin binding) | “Paclitaxel for injection (albumin binding)260mg/m2，I.v., d1” NCT04067102 ↗ |
| Known as | Paclitaxel for injection (albumin-bound) | “Paclitaxel for injection (albumin-bound) uses human serum albumin as the carrier to avoid the use of organic solvents for intravenous injection of paclitaxel, reducing the...” NCT04766827 ↗3“Paclitaxel for Injection (Albumin-bound): 125 mg/m² on Days 1 and 8, every 3 weeks per cycle.” NCT07240766 ↗ “Drug: Paclitaxel for Injection（Albumin Bound）” NCT01494415 ↗ “Paclitaxel for injection(Albumin Bound)” NCT04443036 ↗ |
| Known as | Paclitaxel Injection | “Paclitaxel Injection: 50mg/m², iv, D1, D8; Q3W;” NCT07304258 ↗ |
| Known as | Paclitaxel Micelles | “Paclitaxel Micelles: 230 mg/m² (C1), then 300 mg/m² if tolerated, IV (≥3h), D8, Q3W.” NCT07359053 ↗ |
| Known as | Paclitaxel Polymeric Micelles for Injection | “Paclitaxel Polymeric Micelles for Injection：150mg / m2 intravenously over 3 hours on Days1,8 of each 21-day cycle.” NCT06706895 ↗ |
| Known as | Paclitaxel protein-bound | “Paclitaxel Protein Bound (Abraxane)” NCT03138720 ↗ |
| Known as | Paclitaxel(Sawai),(NK) | “Paclitaxel(Sawai),(NK), Paraplatin(BMS), Carboplatin(SANDOZ)” NCT01506856 ↗ |
| Known as | Paclitaxel: Taxol | “Paclitaxel (Taxol®)” NCT02983045 ↗3“paclitaxel (Taxol)” NCT02059876 ↗ “Paclitaxel: Taxol” NCT00840450 ↗ “Paclitaxel, Taxol” NCT00873119 ↗ |
| Known as | paclitaxol | “Epirubicin 100mg/m2 and cyclophosphamine 600mg/m2 for four cycles followed by paclitaxol 175mg/m2 for four cycles” NCT03242551 ↗1“Apatinib: 500mg, po, qd, every 4 weeks Paclitaxol: 80mg/m2, d1, d8, d15, every 4 weeks” NCT03144843 ↗ |
| Known as | PAX | “Preclinical and clinical investigation of the combination of the antiangiogenesis/anti-invasion agent carboxyamido-triazole (CAI) administered with the cytotoxic agent paclitaxel (PAX).” PMID 11410496 ↗ Jun 2001 |
| Known as | Phyxol | “Paclitaxel (Phyxol) , Cisplatin” NCT00154882 ↗1“Phyxol(Paclitaxel)” NCT00823186 ↗ |
| Known as | PICS | “Paclitaxel Injection Concentrate for Suspension (PICS)” NCT04332549 ↗ |
| Known as | pm-Pac | “Polymeric micellar paclitaxel (pm-Pac) is a novel Cremophor EL-free,” PMID 33130217 ↗ Oct 2020 |
| Known as | PNU-93914 | “PNU-93914 (Liposome Encapsulated Paclitaxel)” NCT00016900 ↗ |
| Known as | Polymeric micellar paclitaxel | “Polymeric micellar paclitaxel (pm-Pac) is a novel Cremophor EL-free,” PMID 33130217 ↗ Oct 2020 |
| Known as | PTX | “To investigate the efficacy and safety of apatinib in combination with paclitaxel (PTX) alone or POF (PTX, oxaliplatin, and 5-fluorouracil) in patients with taxane-resistant...” PMID 33178765 ↗ Oct 202016“By detecting the blood concentration of paclitaxel (PTX), Investigator assume this research can identify the individual differences of PTX pharmacokinetics (PK) parameters” NCT02737709 ↗ “Paclitaxel plus Carboplatin (TC) therapy; Paclitaxel (PTX) 175 mg/m2 + Carboplatin(CBDCA) area under curve(AUC) 6 q3weeks day1, 3 to 6 cycles” NCT04063527 ↗ “BACKGROUND: NK105 is a novel nanoparticle drug delivery formulation that encapsulates paclitaxel (PTX) in polymeric micelles.” PMID 30745582 ↗ Feb 2019 “Paclitaxel (PTX), the most widely used anticancer drug, is applied for the treatment of various types of malignant diseases.” NCT05966441 ↗ “Paclitaxel (PTX) is one of the most potent and commonly used chemotherapies for breast and pancreatic cancer.” PMID 35552677 ↗ Jul 2022 “paclitaxel (PTX) (20 mg/m2 intraperitoneally and 50 mg/m2 intravenously on days 1 and 8)” NCT05204173 ↗ “Patient was first treated with paclitaxel (PTX) chemotherapy 3 cycles (2 weeks regimen).” NCT03544047 ↗ “paclitaxel (PTX) 175 mg/m2 every 3 weeks or paclitaxel (PTX) 80 mg/m2 every week” NCT04172259 ↗ “Drug: Paclitaxel (PTX). Name of Device: Advance PTX” NCT05173857 ↗ “Paclitaxel (PTX) is a common chemotherapeutic agent” NCT06818331 ↗ |
| Known as | S-8184 | “S-8184 Paclitaxel Injectable Emulsion” NCT00034151 ↗2“S-8184 Paclitaxel Injectable Emulsion” NCT00034177 ↗ “S-8184 Paclitaxel Injectable Emulsion” NCT00034190 ↗ |
| Known as | S-8184 Paclitaxel Injectable Emulsion | “A Phase 2 Multicenter Evaluation of the Safety and Efficacy of TOCOSOL(TM) Paclitaxel (S-8184 Paclitaxel Injectable Emulsion) in Patients With Metastatic or Locally Advanced,...” NCT00077688 ↗ |
| Known as | sb-Pac | “solvent-based paclitaxel (sb-Pac) plus cisplatin” PMID 33130217 ↗ Oct 2020 |
| Known as | sb-paclitaxel | “PURPOSE: This phase III trial compared the efficacy and safety of albumin-bound paclitaxel (nab-paclitaxel) plus carboplatin with solvent-based paclitaxel (sb-paclitaxel) plus...” PMID 22547591 ↗ Apr 2012 |
| Known as | solvent-based paclitaxel | “PURPOSE: This phase III trial compared the efficacy and safety of albumin-bound paclitaxel (nab-paclitaxel) plus carboplatin with solvent-based paclitaxel (sb-paclitaxel) plus...” PMID 22547591 ↗ Apr 20121“solvent-based paclitaxel (sb-Pac) plus cisplatin” PMID 33130217 ↗ Oct 2020 |
| Known as | SOR007 | “This Phase 1/2 study evaluated safety and efficacy of a topical submicron particle paclitaxel (SPP) in an anhydrous ointment base (SOR007), primarily in breast cancer patients...” PMID 35471470 ↗ Apr 20221“SOR007 (Uncoated Nanoparticulate Paclitaxel) Ointment” NCT03083470 ↗ |
| Known as | SPP | “This Phase 1/2 study evaluated safety and efficacy of a topical submicron particle paclitaxel (SPP) in an anhydrous ointment base (SOR007), primarily in breast cancer patients...” PMID 35471470 ↗ Apr 2022 |
| Known as | SYHX2011 | “Albumin-Bound Paclitaxel (SYHX2011) in Patients with Advanced Breast Cancer: A Multicenter, Randomized, Double-Blind, Phase III Study.” PMID 42368972 ↗ Jun 2026 |
| Known as | TAX | “OBJECTIVES: I. Determine a safe weekly dose of intravenous estramustine (EM) in combination with paclitaxel (TAX) and carboplatin (CBDCA) in patients with advanced prostate cancer.” NCT00003394 ↗6“Patients also receive paclitaxel (TAX) as a weekly 3 hour infusion on days 1, 8, 15, and 29” NCT00002984 ↗ “OUTLINE: Single-Agent Chemotherapy. Paclitaxel (Bristol-Myers), Taxol, TAX, NSC-125973.” NCT00002632 ↗ “Paclitaxel, TAX, NSC-125973; Cisplatin, CDDP, NSC-119875” NCT00001499 ↗ “plus Paclitaxel (Bristol-Myers), Taxol, TAX, NSC-125973.” NCT00001442 ↗ “TAX Paclitaxel (Bristol-Myers)” NCT00002711 ↗ “TAX(Taxol)” NCT05871918 ↗ |
| Known as | Taxol | “Dose-dense weekly paclitaxel (Taxol) and carboplatin (dd-TC) improved survival compared with conventional tri-weekly paclitaxel and carboplatin (c-TC) as a first-line...” PMID 24356636 ↗ Jan 201482“The purpose of this study is to determine whether a new chemotherapy schedule using biweekly combination of paclitaxel (Taxol®), gemcitabine (Gemzar®) and Avastin would help to...” NCT00618826 ↗ “The purpose of this study is to compare the objective response rates of patients randomized to receive either TOCOSOL(R) Paclitaxel or Taxol(R) (paclitaxel injection)...” NCT00251095 ↗ “The purpose of this study is to find out what effects, good and bad, the chemotherapy drugs gemcitabine (Gemzar) and paclitaxel (Taxol) have in combination with twice daily...” NCT00226746 ↗ “ABI-007 is a new anticancer medication containing the same active ingredient as Taxol, paclitaxel, but formulated as a protein-stabilized material that is suspended in salt...” NCT00046527 ↗ “Evaluation of Paclitaxel (Taxol, NSC #673089), Carboplatin (Paraplatin, NSC #241240), and BSI-201 (NSC #746045, IND #71,677) in the Treatment of Advanced, Persistent, or...” NCT00687687 ↗ “The front-line treatment consists in a combination of epirubicin, (100 mg/m² in a 30-minute infusion), and paclitaxel (Taxol, 250 mg/m² given in a 3-hour infusion),...” NCT00231582 ↗ “A Phase II Study of Weekly Paclitaxel(Taxol)and 24-Hour Infusion High-Dose 5-Fluorouracil and Leucovorin(HDFL)in the Treatment Locally Advanced and Recurrent/Metastatic Gastric Cancers” NCT00154726 ↗ “Randomized, Crossover, Pharmacokinetic Study Of Paclitaxel (Taxol) And ABI-007 (A Cremophor EL-Free, Protein Stabilized, Nanoparticle Paclitaxel) In Patients With Advanced Solid Tumors” NCT00095914 ↗ “A Phase II Study of Carboplatin (CBDCA), Paclitaxel (TAXOL), and Everolimus (RAD001) in Previously Untreated Patients With Measurable Disease With Cancer of Unknown Primary (CUP)” NCT00936702 ↗ “BACKGROUND: To evaluate the activity and safety of nonanthracycline-containing weekly PCb [paclitaxel (Taxol) plus carboplatin] regimen in neoadjuvant treatment of breast cancer.” PMID 20211870 ↗ Mar 2010 |
| Known as | Taxol (paclitaxel) | “Taxol (paclitaxel)” NCT01653912 ↗3“Taxol (Paclitaxel)” NCT02195973 ↗ “taxol (paclitaxel)” NCT00518583 ↗ “Taxol (Paclitaxel)” NCT00249964 ↗ |
| Known as | Taxol (Registered Trademark) | “infusional Taxol® (Registered Trademark) (paclitaxel)” NCT00001384 ↗ |
| Known as | Taxol R | “This is a Phase II study of paclitaxel (Taxol R) administered as a 96-hour (4 day) continuous infusion followed by a bolus of cisplatin for previously untreated patients with...” NCT00001450 ↗ |
| Known as | TOCOSOL | “Experimental Arm: TOCOSOL Paclitaxel” NCT00034177 ↗ |
| Action | Inhibit | “Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop tumor cells from dividing so they stop growing or die.” NCT00091039 ↗ |
| Modality | Small molecule | “Chemotherapy with a platinum agent and a taxane (paclitaxel) is considered the standard of care for treatment of ovarian carcinoma.” PMID 15547181 ↗ Nov 2004 |
| Route | Intravenous | “continuous IV infusion of 120 mg/m(2) over 120 hours” NCT00001442 ↗ |
| Target | TLR4 | “paclitaxel functions as a Toll-like receptor 4 (TLR4) agonist” NCT06845319 ↗ |