drugset / Trial / NCT04889768
HIPEC Combined With Camrelizumab, Paclitaxel and S-1 for Conversion Therapy in Patients With Advanced Gastric Cancer With Peritoneal Metastasis
NaSingle-groupOpen-labelTreatment
Summary
There is no currently available treatment for peritoneal metastasis of gastric cancer. Hyperthermic intraperitoneal chemotherapy (HIPEC) can not only maintain the high concentration of drugs in the abdominal cavity, but also improve the anti-tumor efficacy of chemotherapy drugs through the thermo-thermal effect. In recent years, immunotherapy has made great progress in the treatment of gastric cancer. We want to explore the hyperthermic intraperitoneal chemotherapy (HIPEC) combined with Camrelizumab (SHR-1210) and intravenous chemotherapy for Creating the Operation Chance in advanced gastric cancer with peritoneal metastasis.
Timeline
- Start
- 2021-07-31
- Primary completion
- 2023-07-31
- Completion
- 2025-07-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Camrelizumab | Monoclonal antibody | 200 mg | Intravenous |
| Subject | Paclitaxel | Small molecule | 75 mg/m2 | Other |
| Subject | Paclitaxel | Small molecule | 150 mg/m2 | Other |
| Subject | S-1 | Small molecule | 80 mg/m2 | Oral |
| Subject | S-1 | Small molecule | 120 mg/m2 | Oral |
Indications
No indication recorded.