drugset / Trial / NCT01994031
Dose Escalation and Pharmacokinetic Study of Paclitaxel Liposome Injection in Treating Patients With Advanced Solid Tumor After Failure From Conventional Treatments
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to determine the maximum tolerated dose (MTD)of paclitaxel liposome injection and to compare the pharmacokinetic characters between paclitaxel liposome injection and paclitaxel injection and to value the effectiveness for cancer treatment.
Timeline
- Start
- 2014-08
- Primary completion
- 2015-07
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Paclitaxel | Small molecule | 135 mg/m2 | — |
| Subject | Paclitaxel | Small molecule | 175 mg/m2 | — |
| Subject | Paclitaxel | Small molecule | 210 mg/m2 | — |
| Subject | Paclitaxel | Small molecule | 250 mg/m2 | — |
| Subject | Paclitaxel | Small molecule | 300 mg/m2 | — |