drugset / Trial / NCT05489848

Chemotherapy vs Chemoradiotherapy for Post-operative Endometrial Cancer Patients With P53-mutation

NCT05489848

Phase 2/3 Not yet recruiting 294 enrolled Fudan University
RandomizedParallel-groupOpen-labelTreatment

Summary

Aim to compare chemotherapy alone or chemoradiotherapy for post-operative endometrial cancer (stage I-IVA) with p53 mutation.

Timeline

Start
2022-08-20
Primary completion
2028-08-20
Completion
2030-08-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule Intravenous
Comparator Cisplatin Other / unclassified 50 mg/m2 Intravenous
Subject Paclitaxel Small molecule 135 mg/m2 Intravenous
Subject Paclitaxel Small molecule 175 mg/m2 Intravenous

Indications