drugset / Trial / NCT05338541
Tucidinostat Plus Etoposide in the Treatment of Neuroblastoma in Childhood.
NaSingle-groupOpen-labelTreatment
Summary
Neuroblastoma is a malignant tumor that develops in infants and kids. Dysregulation of histone acetylation is associated with a series of malignant tumors. Neuroblastoma is caused by defective neural crest differentiation due to abnormal gene regulation.
Timeline
- Start
- 2022-05-27
- Primary completion
- 2024-06-30
- Completion
- 2024-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Etoposide | Small molecule | 50 mg/m2 | — |
| Subject | Tucidinostat | Small molecule | 14 mg/m2 | — |
| Subject | Tucidinostat | Small molecule | 17.5 mg/m2 | — |
| Subject | Tucidinostat | Small molecule | 23 mg/m2 | — |