drugset / Trial / NCT05510089

Etoposide+Cytarabine+PEG-rhG-CSF for Hematopoietic Stem Cell Mobilization in Patients With Hematological Malignancies

NCT05510089

NaSingle-groupOpen-labelTreatment

Summary

This is a single-arm, multicenter, exploratory clinical study to evaluate the safety and efficacy of the combination of etoposide, cytarabine and PEG-rhG-CSF (EAP regimen) on hematopoietic stem cell mobilization in poor mobilization patients with hematological malignancies. All eligible patients will receive EAP regimen treatment, then the number of CD34+ cells and white blood cells will be monitoring. When the collection standard is met, hematopoietic stem cell collection will be started.

Timeline

Start
2022-09-01
Primary completion
2024-05-31
Completion
2024-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Cytarabine Small molecule 300 mg/m2
Subject Etoposide Small molecule 75 mg/m2
Subject Pegfilgrastim Protein / enzyme biologic 6 mg