drugset / Trial / NCT03385096
Mel vs BUCY+VP-16 Conditioning Regimen for MM Undergoing Auto-HSCT
Phase 2/3
Unknown
122 enrolled
Nanfang Hospital, Southern Medical University
Guangzhou First People's Hospital · collabSun Yat-Sen Memorial Hospital of Sun Yat-Sen University · collabThird Affiliated Hospital, Sun Yat-Sen University · collabZhujiang Hospital · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the safety and efficacy of Melphalan and BUCY+VP-16 myeloablative conditioning regimens in multiple myeloma undergoing autologous hematopoietic stem cell transplantation.
Timeline
- Start
- 2018-01-02
- Primary completion
- 2020-12
- Completion
- 2021-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Busulfan | Small molecule | 3.2 mg/kg | — |
| Subject | Cyclophosphamide | Other / unclassified | 60 mg/kg | — |
| Subject | Etoposide | Small molecule | 10 mg/kg | — |
| Comparator | Melphalan | Small molecule | 200 mg/m2 | — |