Drugs / Daunorubicin
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Daunorubicin

Small molecule

Developed for
acute myeloid leukemia · leukemia · acute lymphoblastic leukemia · myelodysplastic syndrome · lymphoblastic lymphoma · childhood acute myeloid leukemia · lymphoma · therapy related acute myeloid leukemia and myelodysplastic syndrome
+56 more · myeloid leukemia · acute myeloblastic leukemia with maturation · acute myeloblastic leukemia without maturation · acute myelomonocytic leukemia M4 · acute promyelocytic leukemia · adult acute lymphoblastic leukemia · childhood acute lymphoblastic leukemia · lymphoid leukemia · myelodysplastic/myeloproliferative neoplasm · acute basophilic leukemia · acute erythroid leukemia · acute monocytic leukemia · acute myeloid leukemia with multilineage dysplasia · acute myeloid leukemia, inv(16)(p13.1;q22) · childhood acute megakaryoblastic leukemia · childhood myelodysplastic syndrome · refractory anemia with excess blasts in transformation · sarcoma · acquired polycythemia vera · acute leukemia · acute leukemia of ambiguous lineage · acute myeloid leukemia and myelodysplastic syndromes related to alkylating agent · acute myeloid leukemia with 11q23 abnormalities · acute myeloid leukemia with minimal differentiation · acute myeloid leukemia with t(8;21)(q22;q22) translocation · acute myeloid leukemia, biallelic CEBPA gene mutation · acute myeloid leukemia, FLT3 internal tandem duplication · acute myeloid leukemia, t(16;16)(p13.1;q22) · acute myeloid leukemia, t(8;21)(q22; q22.1) · acute myeloid leukemia, t(9;11)(p21.3;q23.3) · adult acute monocytic leukemia · anaplastic large cell lymphoma · B-cell acute lymphoblastic leukemia · B-cell lymphoma, unclassifiable, with features intermediate between diffuse large b-cell lymphoma and classical Hodgkin lymphoma · breast cancer · Burkitt lymphoma · childhood malignant neoplasm · chronic myeloid leukemia · diffuse large B-cell lymphoma · essential thrombocythemia · hematopoietic and lymphoid cell neoplasm · Hodgkins lymphoma · Kaposi's sarcoma · mixed phenotype acute leukemia · myelofibrosis · myeloid leukemia associated with down syndrome · non-Hodgkin lymphoma · precursor B-cell acute lymphoblastic leukemia · T-cell acute lymphoblastic leukemia · urinary bladder cancer · urothelial carcinoma · acute megakaryoblastic leukemia in adult · acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) · acute myeloid leukemia with mutated NPM1 · acute myeloid leukemia, del(5q31-q32) · early T cell progenitor acute lymphoblastic leukemia
Investigated by
National Cancer Institute (NCI) · Children's Oncology Group · PETHEMA Foundation · St. Jude Children's Research Hospital · Institute of Hematology & Blood Diseases Hospital, China · Jazz Pharmaceuticals
+158 more · SWOG Cancer Research Network · GIMEMA Foundation · AbbVie · Assistance Publique - Hôpitaux de Paris · Deutsche Krebshilfe e.V., Bonn (Germany) · First Affiliated Hospital of Zhejiang University · Johann Wolfgang Goethe University Hospital · Medical Research Council · Memorial Sloan Kettering Cancer Center · Technical University Dresden · Acute Leukemia French Association · Alliance for Clinical Trials in Oncology · CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. · Cooperative Study Group A for Hematology · Dutch Childhood Oncology Group · Eastern Cooperative Oncology Group · European Organisation for Research and Treatment of Cancer - EORTC · Federal Research Institute of Pediatric Hematology, Oncology and Immunology · French Innovative Leukemia Organisation · Goethe University · Hannover Medical School · Italian Association of Pediatric Hematology and Oncology · M.D. Anderson Cancer Center · Qilu Hospital of Shandong University · Roswell Park Cancer Institute · The First Affiliated Hospital of Anhui Medical University · Tongji Hospital · University Hospital Schleswig-Holstein · University Medical Center Hamburg-Eppendorf · AIDS Malignancy Consortium · All India Institute of Medical Sciences · Anhui Medical University · Arog Pharmaceuticals, Inc. · Asan Medical Center · Astellas Pharma Global Development, Inc. · Australian and New Zealand Children's Oncology Group · BFM Austria · BFM Germany · Beat AML, LLC · Beijing 302 Hospital · Bhavana Bhatnagar · CLCG France Belgium Portugal · COALL Germany · CORS Monza Italy · CPH, Czech republic · CSPC ZhongQi Pharmaceutical Technology Co., Ltd. · CTI BioPharma · Cancer Research UK · Celgene Corporation · Changzhou Jinyuan Pharmaceutical Manufacturing Co., Ltd. · Children's Cancer Group, China · Children's Hospital Medical Center, Cincinnati · Children's Hospital of Philadelphia · Children's Hospital of Soochow University · Children's Mercy Hospital Kansas City · Copernicus Memorial Hospital · DFCI consortium USA · Dana-Farber Cancer Institute · Emory University · EsPhALL · Ev. Krankenhaus Essen-Werden · FRALLE France · First Affiliated Hospital of Guangxi Medical University · First Affiliated Hospital, Sun Yat-Sen University · First Hospital of China Medical University · Fresenius Kabi · GWT-TUD GmbH · Genzyme, a Sanofi Company · Georgetown University · Gilead Sciences · Grupo Argentino de Tratamiento de la Leucemia Aguda · Guangdong Provincial People's Hospital · H. Lee Moffitt Cancer Center and Research Institute · HOVON Foundation · all 164 on the full record

Regulatory milestones approvals, filings & regulatory actions · 3 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved EU (EMA) Vyxeos liposomal (previously Vyxeos) 2018-08-23 europa.eu
Label expansion US (FDA) CERUBIDINE 1987-03-06 fda.gov
Approved US (FDA) CERUBIDINE 1979-12-19 fda.gov

Trials 151 · started per year

today
US approved 1979
EU approved 2018
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 113 trials
Phase 1 NCT05453903 Oct 2022 → Oct 2026 expected acute myeloid leukemia Janssen Research & Development, LLC Active not recruiting No outcome recorded
Phase 1 NCT05342584 May 2022 → Dec 2028 expected acute myeloid leukemia, myelodysplastic syndrome Montefiore Medical Center Recruiting No outcome recorded
Phase 1 NCT02971397 Nov 2016 → Mar 2018 acute myeloid leukemia Wake Forest University Health Sciences Completed No outcome recorded
Phase 1 NCT02914977 Nov 2016 → Apr 2019 acute lymphoblastic leukemia, acute myeloid leukemia Tara Lin Completed No outcome recorded
Phase 1 NCT02323607 Jan 2016 → Jul 2018 therapy related acute myeloid leukemia and myelodysplastic syndrome Bhavana Bhatnagar Completed No outcome recorded
Phase 1 NCT02632708 Dec 2015 → Dec 2018 overdue therapy related acute myeloid leukemia and myelodysplastic syndrome Servier Active not recruiting No outcome recorded
Phase 1 NCT02236013 Jan 2015 → Jul 2021 acute myeloid leukemia Astellas Pharma Global Development, Inc. Completed No outcome recorded
Phase 1 NCT01943682 Sep 2013 → Mar 2019 B-cell lymphoma, unclassifiable, with features intermediate between diffuse large b-cell lymphoma and classical Hodgkin lymphoma, Burkitt lymphoma, Hodgkins lymphoma, acute lymphoblastic leukemia +4 Children's Hospital Medical Center, Cincinnati Completed No outcome recorded
Phase 1 NCT00427414 Sep 2008 → Nov 2010 sarcoma AIDS Malignancy Consortium Terminated No outcome recorded
Phase 1 NCT00389428 Sep 2006 → Dec 2008 hematopoietic and lymphoid cell neoplasm Jazz Pharmaceuticals Completed No outcome recorded
Phase 1/29 trials
Phase 1/2 NCT04990102 May 2023 → Dec 2026 expected acute myeloid leukemia Georgetown University Recruiting No outcome recorded
Phase 1/2 NCT04109690 Dec 2019 → Jul 2021 myelodysplastic syndrome Yale University Withdrawn No outcome recorded
Phase 1/2 NCT03850535 Mar 2019 → Sep 2020 acute myeloid leukemia Hoffmann-La Roche Terminated No outcome recorded
Phase 1/2 NCT03878199 Feb 2019 → Feb 2025 acquired polycythemia vera, acute myeloid leukemia, essential thrombocythemia, myelofibrosis Ohio State University Comprehensive Cancer Center Terminated No outcome recorded
Phase 1/2 NCT03013998 Nov 2016 → Dec 2028 expected acute myeloid leukemia Beat AML, LLC Recruiting No outcome recorded
Phase 1/2 NCT00219765 May 2001 → Jan 2006 chronic myeloid leukemia Poitiers University Hospital Terminated No outcome recorded
Phase 1/2 NCT00015860 May 2001 → Oct 2003 leukemia Jonsson Comprehensive Cancer Center Completed No outcome recorded
Phase 1/2 NCT00005793 Jul 1999 → Jul 2006 leukemia H. Lee Moffitt Cancer Center and Research Institute Completed No outcome recorded
Phase 1/2 NCT00002925 Feb 1997 → Nov 2003 leukemia National Cancer Institute (NCI) Completed No outcome recorded
Phase 246 trials
Phase 2 NCT06917911 Feb → Nov 2027 expected core binding factor acute myeloid leukemia National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 2 NCT07548710 May 2026 → May 2027 expected acute myeloid leukemia Ruijin Hospital Recruiting No outcome recorded
Phase 2 NCT06770257 Dec 2025 → Dec 2026 acute myeloid leukemia Institute of Hematology & Blood Diseases Hospital, China Withdrawn No outcome recorded
Phase 2 NCT06930105 Sep 2025 → Nov 2027 expected acute lymphoblastic leukemia Xianmin Song, MD Not yet recruiting No outcome recorded
Phase 2 NCT07078591 Jun 2025 → Jun 2030 expected acute myeloid leukemia Beijing 302 Hospital Recruiting No outcome recorded
Phase 2 NCT05554406 Sep 2024 → Mar 2027 expected acute myeloid leukemia with multilineage dysplasia, therapy related acute myeloid leukemia and myelodysplastic syndrome National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 2 NCT05554393 Sep 2024 → Dec 2027 expected acute myeloid leukemia National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 2 NCT05564390 Jun 2024 → May 2029 expected acute myeloid leukemia with multilineage dysplasia, myelodysplastic syndrome, therapy related acute myeloid leukemia and myelodysplastic syndrome National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 2 NCT05904106 Apr 2024 → Sep 2028 expected acute myeloid leukemia Technical University Dresden Recruiting No outcome recorded
Phase 2 NCT05829434 Mar 2024 → Aug 2028 acute myeloid leukemia, myelodysplastic syndrome Uwe Platzbecker Withdrawn No outcome recorded
Phase 2/37 trials
Phase 2/3 NCT07651163 Mar 2026 → Dec 2029 expected acute myeloid leukemia First Affiliated Hospital of Zhejiang University Enrolling by invitation No outcome recorded
Phase 2/3 NCT07651176 Mar 2026 → Dec 2029 expected acute myeloid leukemia First Affiliated Hospital of Zhejiang University Enrolling by invitation No outcome recorded
Phase 2/3 NCT00454480 Aug 2006 → Aug 2012 leukemia, myelodysplastic syndrome The University of New South Wales Completed No outcome recorded
Phase 2/3 NCT00111345 Mar 2004 → Mar 2012 myeloid leukemia University Hospital Muenster Unknown No outcome recorded
Phase 2/3 NCT01015196 Jan 2001 → ? acute myeloid leukemia Nantes University Hospital Completed No outcome recorded
Phase 2/3 NCT00209833 Jan 1999 → Sep 2005 acute myeloid leukemia, refractory anemia with excess blasts in transformation Hannover Medical School Unknown No outcome recorded
Phase 2/3 NCT00002499 Jan 1990 → ? leukemia Grupo Argentino de Tratamiento de la Leucemia Aguda Unknown No outcome recorded
Phase 345 trials
Phase 3 NCT07232134 Jul 2025 → Jul 2030 expected Down syndrome, acute myeloid leukemia Federal Research Institute of Pediatric Hematology, Oncology and Immunology Recruiting No outcome recorded
Phase 3 NCT06182592 Jan 2024 → Feb 2026 overdue acute myeloid leukemia CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. Not yet recruiting No outcome recorded
Phase 3 NCT04184505 Nov 2020 → Mar 2026 overdue myelodysplastic syndrome GIMEMA Foundation Recruiting No outcome recorded
Phase 3 NCT04293562 Jul 2020 → Jun 2029 expected acute myeloid leukemia Children's Oncology Group Recruiting No outcome recorded
Phase 3 NCT03507842 Mar 2018 → Dec 2028 expected acute myeloid leukemia Asan Medical Center Enrolling by invitation No outcome recorded
Phase 3 NCT03007147 Aug 2017 → Sep 2027 expected B-cell acute lymphoblastic leukemia, T-cell acute lymphoblastic leukemia, mixed phenotype acute leukemia Children's Oncology Group Active not recruiting No outcome recorded
Phase 3 NCT02724163 Apr 2016 → Dec 2031 expected acute myeloid leukemia University of Birmingham Active not recruiting No outcome recorded
Phase 3 NCT02845882 Jan 2016 → Dec 2023 overdue lymphoblastic lymphoma Children's Cancer Group, China Active not recruiting No outcome recorded
Phase 3 NCT02521493 Dec 2015 → Jun 2024 overdue Down syndrome, myelodysplastic syndrome, myeloid leukemia associated with down syndrome Children's Oncology Group Active not recruiting No outcome recorded
Phase 3 NCT02072811 Feb 2014 → Feb 2018 acute myeloid leukemia dr hab. n. med. Agnieszka Wierzbowska Unknown No outcome recorded
Phase 413 trials
Phase 4 NCT01987297 Jun 2012 → Dec 2020 acute promyelocytic leukemia Shanghai Jiao Tong University School of Medicine Unknown No outcome recorded
Phase 4 NCT02894645 Oct 2008 → Oct 2018 childhood acute lymphoblastic leukemia National University Hospital, Singapore Unknown No outcome recorded
Phase 4 NCT02036489 Jan 2008 → Dec 2019 acute lymphoblastic leukemia PETHEMA Foundation Completed No outcome recorded
Phase 4 NCT00526409 Jun 2005 → Oct 2014 acute lymphoblastic leukemia PETHEMA Foundation Completed No outcome recorded
Phase 4 NCT00180167 Jan 2005 → Jul 2010 acute myeloid leukemia Technical University Dresden Completed No outcome recorded
Phase 4 NCT00199017 Apr 2004 → Mar 2009 lymphoblastic lymphoma Johann Wolfgang Goethe University Hospital Completed No outcome recorded
Phase 4 NCT00853008 Jan 2003 → Nov 2012 acute lymphoblastic leukemia PETHEMA Foundation Completed No outcome recorded
Phase 4 NCT00526175 Jun 2001 → May 2015 acute lymphoblastic leukemia PETHEMA Foundation Completed No outcome recorded
Phase 4 NCT00180128 Jan 2000 → Nov 2012 acute promyelocytic leukemia Technical University Dresden Unknown No outcome recorded
Phase 4 NCT00526305 Jan 2000 → Apr 2005 acute lymphoblastic leukemia PETHEMA Foundation Completed No outcome recorded
Phase not applicable18 trials
NCT07495631 Apr 2026 → Mar 2028 expected adult acute lymphoblastic leukemia Institute of Hematology & Blood Diseases Hospital, China Recruiting No outcome recorded
NCT07443592 Mar 2026 → Mar 2031 expected acute lymphoblastic leukemia PETHEMA Foundation Not yet recruiting No outcome recorded
NCT06697327 Feb → Aug 2025 overdue acute myeloid leukemia Anhui Medical University Enrolling by invitation No outcome recorded
NCT07131059 May 2024 → May 2026 overdue acute myeloid leukemia Institute of Hematology & Blood Diseases Hospital, China Recruiting No outcome recorded
NCT04179929 Nov 2019 → Nov 2026 expected acute lymphoblastic leukemia PETHEMA Foundation Recruiting No outcome recorded
NCT02551718 Sep 2015 → Jun 2020 acute leukemia of ambiguous lineage, acute lymphoblastic leukemia University of Washington Completed No outcome recorded
NCT02519712 Jul 2015 → Sep 2017 acute myeloid leukemia Memorial Sloan Kettering Cancer Center Terminated No outcome recorded
NCT02432872 Apr 2015 → May 2018 acute myeloid leukemia Jianxiang Wang Unknown No outcome recorded
NCT01156883 Apr 2010 → Oct 2017 leukemia GIMEMA Foundation Completed No outcome recorded
NCT01953770 Feb 2008 → Jan 2015 childhood acute lymphoblastic leukemia Federal Research Institute of Pediatric Hematology, Oncology and Immunology Unknown No outcome recorded
Also used as a comparator or background therapy in 219 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT03568994 Background Jul 2018 → Sep 2020 acute myeloid leukemia Baylor College of Medicine Completed No outcome recorded
Phase 134 trials
Phase 1 NCT07052994 Background May 2026 childhood leukemia M.D. Anderson Cancer Center Withdrawn No outcome recorded
Phase 1 NCT06313437 Background Dec 2024 → Mar 2027 expected acute myeloid leukemia Dana-Farber Cancer Institute Recruiting No outcome recorded
Phase 1 NCT05886049 Background Jun 2024 → Dec 2027 expected acute myeloid leukemia with mutated NPM1, acute myeloid leukemia, MLL gene rearrangement National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 1 NCT06226571 Background May 2024 → Feb 2027 expected acute myeloid leukemia Syndax Pharmaceuticals Active not recruiting No outcome recorded
Phase 1 NCT05735184 Background Jul 2023 → Apr 2030 expected acute myeloid leukemia with mutated NPM1, acute myeloid leukemia, MLL gene rearrangement, myeloid sarcoma Kura Oncology, Inc. Recruiting No outcome recorded
Phase 1/217 trials
Phase 1/2 NCT07585734 Background Apr 2025 → Apr 2026 T-cell acute lymphoblastic leukemia Institute of Hematology & Blood Diseases Hospital, China Withdrawn No outcome recorded
Phase 1/2 NCT06746519 Background Dec 2024 → Dec 2025 overdue acute myeloid leukemia Chen Suning Recruiting No outcome recorded
Phase 1/2 NCT04988555 Background Feb 2022 → Jun 2027 expected acute lymphoblastic leukemia, acute myeloid leukemia, myelodysplastic syndrome, plasma cell myeloma Sumitomo Pharma America, Inc. Recruiting No outcome recorded
Phase 1/2 NCT04817241 Comparator Feb 2022 → Jun 2025 overdue acute myeloid leukemia National Cancer Institute (NCI) Active not recruiting No outcome recorded
Phase 1/2 NCT05445154 Background Aug 2021 → Oct 2024 overdue acute myeloid leukemia CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Recruiting No outcome recorded
Phase 268 trials
Phase 2 NCT07636564 Background Oct 2026 → Apr 2031 expected B-cell acute lymphoblastic leukemia, T-cell acute lymphoblastic leukemia, acute leukemia of ambiguous lineage SWOG Cancer Research Network Not yet recruiting No outcome recorded
Phase 2 NCT07664839 Comparator Jul 2026 → May 2028 expected acute myeloid leukemia with mutated NPM1 Shen yang Not yet recruiting No outcome recorded
Phase 2 NCT07228273 Comparator Dec 2025 → Jun 2029 expected acute myeloid leukemia, myelodysplastic syndrome OHSU Knight Cancer Institute Recruiting No outcome recorded
Phase 2 NCT06918431 Background Oct 2025 → Mar 2029 expected B-cell acute lymphoblastic leukemia, lymphoblastic lymphoma City of Hope Medical Center Recruiting No outcome recorded
Phase 2 NCT07512700 Comparator Sep 2025 → Sep 2028 expected acute monocytic leukemia Chinese PLA General Hospital Recruiting No outcome recorded
Phase 2/310 trials
Phase 2/3 NCT07072585 Background Aug 2026 → Sep 2035 expected T-cell acute lymphoblastic leukemia, T-lymphoblastic lymphoma Children's Oncology Group Not yet recruiting No outcome recorded
Phase 2/3 NCT07255872 Background Mar 2026 → Dec 2027 expected acute myeloid leukemia Sichuan Baili Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 2/3 NCT05939180 Comparator Apr 2024 → Oct 2025 overdue acute myeloid leukemia The First Affiliated Hospital of Soochow University Recruiting No outcome recorded
Phase 2/3 NCT03701308 Background Mar 2019 → Oct 2024 overdue acute myeloid leukemia National Cancer Institute (NCI) Active not recruiting No outcome recorded
Phase 2/3 NCT03117751 Background Mar 2017 → Sep 2026 expected lymphoblastic leukemia, acute, with lymphomatous features St. Jude Children's Research Hospital Active not recruiting No outcome recorded
Phase 374 trials
Phase 3 NCT07407140 Comparator Apr 2026 → Feb 2029 expected acute myeloid leukemia Institute of Hematology & Blood Diseases Hospital, China Not yet recruiting No outcome recorded
Phase 3 NCT07223814 Background Mar 2026 → Jun 2030 expected acute myeloid leukemia HOVON Foundation Recruiting No outcome recorded
Phase 3 NCT07211958 Background Nov 2025 → Jun 2029 expected acute myeloid leukemia Syndax Pharmaceuticals Recruiting No outcome recorded
Phase 3 NCT07007312 Background Sep 2025 → Nov 2031 expected acute myeloid leukemia Kura Oncology, Inc. Recruiting No outcome recorded
Phase 3 NCT07132684 Comparator Aug 2025 → Aug 2027 expected acute myeloid leukemia Institute of Hematology & Blood Diseases Hospital, China Recruiting No outcome recorded
Phase 47 trials
Phase 4 NCT06289673 Background Dec 2024 → May 2034 expected acute lymphoblastic leukemia, lymphoblastic lymphoma, mixed phenotype acute leukemia St. Jude Children's Research Hospital Recruiting No outcome recorded
Phase 4 NCT07561892 Background Apr 2022 → Dec 2026 expected acute myeloid leukemia, chemotherapy-induced toxicity Fujian Medical University Union Hospital Recruiting No outcome recorded
Phase 4 NCT03026842 Comparator Jan 2017 → Dec 2023 acute myeloid leukemia The First Hospital of Jilin University Unknown No outcome recorded
Phase 4 NCT01191541 Background May 2010 → Feb 2017 leukemia Xiaofan Zhu Completed No outcome recorded
Phase 4 NCT01587430 Comparator Jan 2010 → Apr 2014 acute myeloid leukemia National Research Center for Hematology, Russia Unknown No outcome recorded
Phase not applicable7 trials
NCT07454226 Background May 2026 → Mar 2028 expected acute lymphoblastic leukemia, phosphohydroxylysinuria Institute of Hematology & Blood Diseases Hospital, China Recruiting No outcome recorded
NCT06841952 Comparator Feb 2025 → Dec 2028 expected acute myeloid leukemia The First Affiliated Hospital of Soochow University Not yet recruiting No outcome recorded
NCT06529250 Comparator Aug 2024 → Aug 2026 overdue acute myeloid leukemia Institute of Hematology & Blood Diseases Hospital, China Recruiting No outcome recorded
NCT05832320 Comparator Jan 2023 → Dec 2024 acute promyelocytic leukemia Peking University People's Hospital Unknown No outcome recorded
NCT03446638 Comparator May 2019 → Aug 2021 myelodysplastic syndrome University of Florida Withdrawn No outcome recorded
Phase not stated1 trial
NCT01085617 Background Dec 2010 → Feb 2025 leukemia, mouth disorder, mucositis University College, London Completed No outcome recorded

Evidence & citations 17 cited values

Every value below carries the sentence it was read from. 371 sources stand behind the page.

FieldValueCited text
Known as daunorubicin “In the control arm, patients received other physician-directed regimen including fludarabine, cytarabine with/without granulocyte stimulating factor(FLA±G) regimen,cytarabine...” NCT02937662
308

“Standard Chemotherapy includes IA(Idarubicin combined with Cytarabine) or DA(Daunorubicin combined with Cytarabine). IDA is given by venous drip daily at 12mg/m2, or DNR is...” NCT06810791

“Therapy of AML in Patients Older Than 60 Years: Randomized Comparison of a Double Induction With Daunorubicin and AraC (as Continuous Infusion) With a Double Induction With...” NCT00180167

“Patients will receive 100-200 mg/m2 per day intravenously of cytarabine for 7 days, plus either 45-60 mg/m2 per day intravenously of daunorubicin or 9-12 mg/m2 per day...” NCT03446638

“with varied cycles, including Daunorubicin, Vincristine, Prednisone, Pegaspargase, Rituximab, Cytarabine, Mercaptopurine, Cyclophosphamide, Methotrexate, Doxorubicin,...” NCT04845035

“A Phase I-II Study of a Liposomal Formulation of Cytarabine and Daunorubicin (CPX-351) in Patients Treated for Higher-risk Myelodysplastic Syndromes Experiencing...” NCT04109690

“CPX-351 is a formulation of two drugs, cytarabine and daunorubicin, that is administered as the first part of treatment to get rid of as many leukemia cells in your bone marrow...” NCT04209725

“Chemotherapy agents for reinduction include vincristine, dexamethasone, polyethylene glycol (PEG)-asparaginase (Erwinia asparaginase when PEG-asparaginase is not available),...” NCT04501614

“For FLT3/IDH1 wild-type participants who are eligible for chemotherapy, Anthracycline: Daunorubicin (DNR) 45 mg/m² per day on Days 1-3, or Idarubicin (IDA) 6 mg/m² per day on Days 1-3.” NCT07548710

“Multi-agent chemotherapy including vincristine, prednisone, daunorubicin, cyclophosphamide, pegaspargase, cytarabine, 6-MP, MTX, and dexamethasone per protocol phases.” NCT07454226

“Participants will be uniformly treated with four drug-induction: vincristine (VCR), prednisone (PDN), pegylated asparaginase (PegASP), daunorubicin (DNR).” NCT07443592

“CPX-351 is made up of two chemotherapy drugs that patients may have already received called cytarabine and daunorubicin that are now packaged together.” NCT01943682

“Patients will be uniformly treated with four drug-induction: vincristine (VCR), prednisone (PDN), pegylated asparaginase (PegASP), daunorubicin (DNR).” NCT04179929

“VDCLP regimen (vincristine, daunorubicin, cyclophosphamide, L-asparaginase, and prednisone) combined with CM313 at the RP2D during induction therapy.” NCT07585734

Daunorubicin or idarubicin will only be used during induction in patients \<65 with presenting white blood cell count (WBC) ≥ 10 x 10\^9/L.” NCT04687176

“To determine, compared with Daunorubicin(DNR), whether Pegylated liposomal doxorubicin (PLD) inducing higher complete remission (CR) rate” NCT02070523

“high dose ARA-C consolidation together with high cumulative dose of anthracyclines daunorubicin, idarubicin, mitoxantrone(720-660 mg/m2)” NCT01587430

“ADE chemotherapy Cytarabine (100mg/m2 d1-d10 BD), Daunorubicin (50mg/m2 d1-d3) and Etoposide (100 mg/m2 d1-5) over a period of 10 days” NCT03053206

“Along with the study drug/placebo, chemotherapy was given as well: either Daunorubicin or Idarubicin and Cytarabine - all taken by i.v.” NCT03512197

“The patients were then randomly assigned to receive two courses of daunorubicin (DNR, no- Ara-C group) or DNR + Ara-C (Ara-C group).” PMID 29615003 Apr 2018

“Participants will receive commercially available cytarabine (cytosine arabinoside) and anthracycline (daunorubicin or idarubicin).” NCT06578247

“DaunoXome (Liposomal Daunorubicin) Plus Ara-C Versus Daunorubicin Plus Ara-C in Elderly AML Patients.A Randomized Phase III Study.” NCT00589082

“Induction: Participants will receive an intravenous (IV), 2-drug combination of cytarabine and either daunorubicin or idarubicin.” NCT06226571

“First consolidation course: daunorubicin 45 mg/m2 x 1 (iv infusion) day 1-3 and cytarabine 1000 mg/m2 x 2 (iv infusion) day 1-4.” NCT01794169

“Patients with newly diagnosed AML will receive standard induction chemotherapy with daunorubicin and cytarabine (7+3 scheme).” NCT02519712

“During Cycle 1, participants will receive prednisone, vincristine, pegaspargase/calaspargase pegol-mknL, and daunorubicin.” NCT05326516

“Participants will receive an intensive chemotherapy regimen of cytarabine and daunorubicin by intravenous (IV) infusion.” NCT07211958

“Participants will receive commercially available cytarabine (cytosine arabinoside) and anthracycline (daunorubicin).” NCT06841952

“intensive chemotherapy(cytarabine with idarubicin or daunorubicin), which short as"7+3 induction regimen"” NCT06746519

“Vincristine, daunorubicin, cyclophosphamide, pegaspargase, prednisone, and venetoclax.” NCT07495631

“induction chemotherapy with IV daunorubicin 45 mg/m\^2 and cytarabine 100 mg/m\^2/day” NCT00943553

“Either daunorubicin or idarubicin was administered via slow intravenous (IV) push” NCT05020665

“Cycle 1: VDCP regimen (Vincristine, Daunorubicin, Cyclophosphamide, Prednisone).” NCT06930105

Daunorubicin 25 milligrams per square meter per week, intravenously, days 5; 12” NCT02451774

“Cytarabine 200 mg/m2/d civ x 7 days Daunorubicin 90 mg/m2/d civ x 3 days” NCT00474006

Daunorubicin 60mg/m2 daily by i.v. infusion on days 1, 3 and 5 (3 doses)” NCT02272478

“Each vial contains 44 mg of daunorubicin and 100 mg of cytarabine.” NCT04230239

Daunorubicin 90 mg/m2/day by continuous iv infusion (d1-3)” NCT00844298

daunorubicin (60 mg/m²) infusion (15-30 min) for 3 days” NCT02172872

daunorubicin (DNR) on days 8, 15, 22 and 29 (4 doses)” NCT01117441

Daunorubicin 90 mg/m2/day iv daily for 3 days (D 1-3)” NCT01690065

Daunorubicin 90 mg/m2 intravenous piggyback days 1-3” NCT02084563

“Drug :SKLB1028 ;Drug: Cytarabine ;Drug: DaunorubicinNCT05445154

daunorubicin or idarubicin, Rubidomycin or Idamycin” NCT03760445

“Intravenous daunorubicin 60 mg/m2/day from D1 to D3” NCT01455025

Daunorubicin/ Cytarabine or Idarubicin/Cytarabine” NCT04676243

“Idarubicin 8mg/m2 or Daunorubicin 45mg/m2 daily.” NCT01987297

“DA regimen: 1.Daunorubicin(60 mg/m2) for 3 days.” NCT07512700

Daunorubicin at 60 mg/m² on study days 3, 4, 5” NCT05829434

Daunorubicin 8.8mg/m2 + cytarabine 20mg/m2” NCT04990102

daunorubicin,cytarabine,homoharringtonine” NCT04415008

“60 mg/m\^2 daunorubicin i.v. on days 3-5” NCT05904106

“cytarabine + daunorubicin induction, 7+3” NCT04988555

Daunorubicin: 60 mg/m\^2 on days 1 to 3” NCT07514936

“and daunorubicin 60 mg/m2 IV (days 1-3)” NCT04628026

“DAC (Daunorubicin + AraC + Cladribine)” PMID 31661339 Oct 2019

Daunorubicin: (DNR 40mg/㎡/d, day 1-3)” NCT06529250

Daunorubicin(45mg/m2/day,days 1 to 3)” NCT06084819

“Dabrafenib Dasatinib Daunorubicin HCl” NCT02551718

daunorubicin IV on days 1, 8, and 15” NCT00022126

“Dasatinib, Daunorubicin, Decitabine” NCT02788201

Daunorubicin(60 mg/m2) for 3 days.” NCT06068621

Daunorubicin(60 mg/m2) for 3 days.” NCT06928376

Daunorubicin, Cytarabine” NCT03257241

daunorubicinNCT06451861

DaunorubicinNCT06529250

DaunorubicinNCT02665065

NCT00853008

NCT03026842

NCT07228273

NCT00931138

NCT02419469

NCT00927498

NCT01349972

NCT02140242

NCT01382147

NCT06313437

NCT00005823

NCT00002658

NCT07072585

NCT01477606

NCT05832320

NCT00764907

NCT03724084

NCT03591510

NCT03701308

NCT00061945

NCT02632708

NCT02971397

NCT02403310

NCT01253070

NCT02326584

NCT05453903

NCT00022737

NCT00002704

NCT00866749

NCT00003190

NCT04061239

NCT00121303

NCT00039117

NCT02834390

NCT07052994

NCT02668653

NCT01451515

NCT03563560

NCT00002700

NCT00004056

NCT03709758

NCT00866307

NCT03444649

NCT01890746

NCT00005793

NCT00915252

NCT00003728

NCT00002531

NCT02776605

NCT05361057

NCT00004128

NCT03836209

NCT03507842

NCT03897127

NCT00363025

NCT00703820

NCT02845882

NCT01265199

NCT04385290

NCT02303821

NCT00002517

NCT00003783

NCT00002590

NCT02112916

NCT00015860

NCT02582359

NCT03117751

NCT01390337

NCT00268229

NCT02036489

NCT07132684

NCT00372593

NCT03013998

NCT04778397

NCT06697327

NCT00715637

NCT00002093

NCT00550992

NCT00526409

NCT03298984

NCT04817241

NCT06635681

NCT03878199

NCT01999413

NCT01463046

NCT00343369

NCT00003650

NCT02343939

NCT06451861

NCT04801797

NCT03900949

NCT07407140

NCT06210750

NCT00526305

NCT03164057

NCT07131059

NCT00526175

NCT06533748

NCT00066794

NCT00187057

NCT03379727

NCT04326439

NCT00369317

NCT00004207

NCT00458848

NCT00124644

NCT01324063

NCT00023777

NCT05735184

NCT02914977

NCT02198482

NCT01256398

NCT02038777

NCT04659616

NCT06744556

NCT03643276

NCT06744504

NCT00004215

NCT00613457

NCT00002756

NCT00276601

NCT00130195

NCT03390387

NCT02954653

NCT00004217

NCT06770257

NCT00850382

NCT02085408

NCT00389428

NCT00198991

NCT00002499

NCT00002549

NCT00019409

NCT00003437

NCT00004228

NCT01371981

NCT00195871

NCT03416179

NCT00184041

NCT06361329

NCT00187005

NCT01546038

NCT00199004

NCT01696084

NCT05726110

NCT04214249

NCT00199017

NCT00003436

NCT03962465

NCT00005603

NCT07223814

NCT02283177

NCT00131027

NCT02472626

NCT07078591

NCT03286634

NCT00002985

NCT07232134

NCT03568994

NCT00085124

NCT05554393

NCT02894645

NCT04174612

NCT01004497

NCT00129168

NCT05554406

NCT02660762

NCT04562792

NCT00549848

NCT05939180

NCT00111345

NCT07664839

NCT00005942

NCT06262438

NCT00180128

NCT02828358

NCT00018954

NCT05886049

NCT06124157

NCT00558519

NCT00186966

NCT02521493

NCT01953770

NCT01806571

NCT00005945

NCT01228331

NCT02432872

NCT04043494

NCT01920737

NCT00003423

NCT00199056

NCT04293562

NCT00137111

NCT02236013

NCT00101153

NCT06317662

NCT00136084

NCT06390319

NCT07255872

NCT00003671

NCT00046930

NCT02393859

NCT07651163

NCT05342584

NCT00199069

NCT06497062

NCT03135028

NCT00427414

NCT06289673

NCT02560025

NCT00494897

NCT00003700

NCT02416388

NCT07651176

NCT00651261

NCT02523976

NCT05681260

NCT07007312

NCT00109837

NCT06182592

NCT00003934

NCT02013648

NCT00618501

NCT01225874

NCT00005962

NCT01145846

NCT00814164

NCT00049517

NCT00002691

NCT00788892

NCT00266136

NCT00002925

NCT03850535

NCT04440267

NCT02323607

NCT01773408

NCT00002471

NCT03959085

NCT02881086

NCT05660473

NCT02003222

NCT06345365

Known as Adriamycin “Daunorubicin, AdriamycinNCT00199069
Known as Cerubidine ClinicalTrials.gov intervention name — accepted as the source's own label NCT01015196
Known as Daunomycin “Daunorubicin, Daunomycin, DNM, DNR, NSC-82151” NCT01324063
8

Daunomycin 20 mg/m2/week IV days 1,15” NCT00187057

NCT03021330

NCT00187122

NCT00176462

NCT00085709

NCT07561892

NCT00610883

NCT00136448

Known as daunorubicin hydrochloride “Patients receive dasatinib and dexamethasone as in RIT, cyclophosphamide IV on day 1, daunorubicin hydrochloride IV and vincristine sulfate IV on days 1 and 8” NCT01256398
65

daunorubicin hydrochloride IV on days 1, 8, 15, and 22” NCT00558519

daunorubicin hydrochloride (DNR) IV over 1 hour” NCT00550992

daunorubicin hydrochloride IV on days 1-3” NCT00061945

“Drug: daunorubicin hydrochlorideNCT00003700

“Drug: daunorubicin hydrochlorideNCT00046930

“Drug: Daunorubicin HydrochlorideNCT03900949

“Drug: daunorubicin hydrochlorideNCT00022126

“Drug: daunorubicin hydrochlorideNCT00121303

“Drug: daunorubicin hydrochlorideNCT00004056

“Drug: Daunorubicin HydrochlorideNCT02521493

“Drug: daunorubicin hydrochlorideNCT00002756

“Drug: daunorubicin hydrochlorideNCT00002704

“Drug: daunorubicin hydrochlorideNCT00004228

“Drug: Daunorubicin HydrochlorideNCT02323607

“Drug: Daunorubicin HydrochlorideNCT03724084

“Drug: daunorubicin hydrochlorideNCT00022737

“Drug: Daunorubicin HydrochlorideNCT02971397

“Drug: Daunorubicin HydrochlorideNCT01253070

daunorubicin hydrochlorideNCT00002499

NCT06917911

NCT02883049

NCT01627041

NCT00070174

NCT05955261

NCT00002798

NCT00275106

NCT03150693

NCT00840684

NCT01156883

NCT00002766

NCT00002532

NCT00416598

NCT00005863

NCT00002514

NCT07636564

NCT06918431

NCT01238211

NCT00002665

NCT01117441

NCT00544999

NCT00002812

NCT00016302

NCT00408005

NCT00096135

NCT00671034

NCT00075725

NCT00557193

NCT00006363

NCT00005596

NCT05157971

NCT01802333

NCT00005585

NCT00093600

NCT02835222

NCT00002785

NCT00742625

NCT00454480

NCT03007147

NCT00430118

NCT00720109

NCT00003593

NCT01085617

NCT02029950

NCT05564390

NCT00002744

Known as daunorubicin liposomal “Patients receive daunorubicin liposomal IV over a minimum of 2 hours on day 1.” NCT00004207
Known as Daunorubicine “1. cycle (induction): i.v. 3+7 (Citarabine 200 mg/m2 iv continuous infusion (24 h) for 7 days, Daunorubicine 60 mg/mq iv day 1-3)” NCT04184505
7

“3+7 (cytarabine and daunorubicine or idarubicine)” NCT06713837

NCT00449319

NCT00428558

NCT00219765

NCT00537550

NCT00589082

NCT00209833

Known as DaunoXome DaunoXome (Liposomal Daunorubicin) Plus Ara-C Versus Daunorubicin Plus Ara-C in Elderly AML Patients.A Randomized Phase III Study.” NCT00589082
4

“Patients are randomly assigned to receive doxorubicin HCl liposome (Doxil) or daunorubicin (DaunoXome) in a 3:1 ratio.” NCT00002985

“In the first course there will be a randomisation for liposomal daunorubicin (DaunoXome®) to be added or not.” NCT00186966

NCT01828489

NCT01117441

Known as DNM “Daunorubicin, Daunomycin, DNM, DNR, NSC-82151” NCT01324063
Known as DNR “The study included 727 older patients with AML (median age, 67 years) treated in two idarubicin (IDA) versus daunorubicin (DNR) Acute Leukemia French Association trials.” PMID 23248249 Dec 2012
25

“Participants will be uniformly treated with four drug-induction: vincristine (VCR), prednisone (PDN), pegylated asparaginase (PegASP), daunorubicin (DNR).” NCT07443592

“Patients will be uniformly treated with four drug-induction: vincristine (VCR), prednisone (PDN), pegylated asparaginase (PegASP), daunorubicin (DNR).” NCT04179929

“To determine, compared with Daunorubicin(DNR), whether Pegylated liposomal doxorubicin (PLD) inducing higher complete remission (CR) rate” NCT02070523

“The patients were then randomly assigned to receive two courses of daunorubicin (DNR, no- Ara-C group) or DNR + Ara-C (Ara-C group).” PMID 29615003 Apr 2018

“Patients receive daunorubicin (DNR) IV over 15-30 minutes and vincristine (VCR) IV over 3-5 minutes on days 1, 8, 15, and 22” NCT00002514

“Daunorubicin(DNR) induction : 60 mg/m2/day IV (30 min), Days 1,2,3” NCT00927498

“daunorubicin hydrochloride (DNR) once weekly in weeks 2-5” NCT00613457

“daunorubicin hydrochloride (DNR) once weekly in weeks 2-5” NCT00430118

“daunorubicin (DNR) on days 8, 15, 22 and 29 (4 doses)” NCT01117441

“daunorubicin (DNR) IV over 1-4 hours on days 8 and 15” NCT00003728

“Daunorubicin (DNR): 45 mg/m2 IV days 1, 8, 15 and 22.” NCT02776605

“Daunorubicin (DNR): 30 mg/m2, i.v., days 8 and 15.” NCT00526175

“Daunorubicin (DNR): 60 mg/m2 i.v., days 1 and 8.” NCT00526305

“daunorubicin (DNR ) 30 mg/m2 iv on days 1 and 8.” NCT02036489

“daunorubicin hydrochloride (DNR) IV over 1 hour” NCT00550992

“Daunorubicin (DNR): 60 mg/m2 IV d 1, 8, 15, 22” NCT00853008

“Daunorubicin, Daunomycin, DNM, DNR, NSC-82151” NCT01324063

“Daunorubicin (DNR) 30 mg/m2/day IV on D1-3” NCT05660473

“Daunorubicin: (DNR 40mg/㎡/d, day 1-3)” NCT06529250

“Daunorubicin, DNR, NSC-82151” NCT00002499

“Daunorubicin, DNR, NSC-82151” NCT00002471

DNR Daunorubicin, NSC-82151” NCT00002549

DNR Daunorubicin, NSC-82151” NCT00002691

“NSC-34521 DNR Daunorubicin” NCT00002704

“Drug: Daunorubicin (DNR)” NCT02881086

Known as liposomal cytarabine/daunorubicin ClinicalTrials.gov intervention name — accepted as the source's own label NCT03760445
Known as Liposomal daunorubicin “The main purpose of this study is to determine the efficacy and toxicity of liposomal daunorubicin when added to fludarabine, ara-C and G-CSF(FLAG) in children with relapsed...” NCT00186966
2

NCT03860844

NCT02724163

Known as NSC-34521 NSC-34521 DNR Daunorubicin” NCT00002704
Known as NSC-82151 “Daunorubicin, Daunomycin, DNM, DNR, NSC-82151NCT01324063
3

“Daunorubicin, DNR, NSC-82151NCT00002499

“Daunorubicin, DNR, NSC-82151NCT00002471

“DNR Daunorubicin, NSC-82151NCT00002691

Action Inhibit “it inhibits p-beta-catenin S552 in humans.” NCT02914977
Modality Small molecule “Anthracycline” NCT02724163
Route Intravenous “daunorubicin (DNR) IV over 15-30 minutes” NCT00002514