drugset / Trial / NCT00015860

STI571 Plus Combination Chemotherapy in Treating Patients With Chronic Myelogenous Leukemia or Acute Lymphocytic Leukemia

NCT00015860

Treatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. STI571 may stop the growth of leukemia cells. Combining chemotherapy and STI571 may kill more cancer cells. PURPOSE: Phase I/II trial to study the effectiveness of combination chemotherapy plus STI571 in treating patients who have chronic myelogenous leukemia or acute lymphocytic leukemia.

Timeline

Start
2001-05
Primary completion
Completion
2003-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Daunorubicin Small molecule Intravenous
Subject Imatinib Small molecule Oral
Background Prednisone Other / unclassified Oral
Background Vincristine Small molecule Intravenous

Indications