drugset / Trial / NCT00343369
Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia
RandomizedTreatment
Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating acute lymphoblastic leukemia. PURPOSE: This randomized phase III trial is studying different combination chemotherapy regimens to compare how well they work in treating young patients with acute lymphoblastic leukemia.
Timeline
- Start
- 2003-01
- Primary completion
- —
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | — | Intravenous |
| Subject | Cytarabine | Small molecule | — | Intravenous |
| Subject | Daunorubicin | Small molecule | — | Intravenous |
| Subject | Dexamethasone | Small molecule | — | Oral |
| Subject | Doxorubicin | Other / unclassified | — | Intravenous |
| Subject | Methotrexate | Small molecule | — | Intravenous |
| Subject | Pegaspargase | Protein / enzyme biologic | — | Intramuscular |
| Subject | Thioguanine | Small molecule | — | Oral |
| Subject | Vincristine | Small molecule | — | Intravenous |
| Subject | asparaginase | Protein / enzyme biologic | — | Intramuscular |
| Background | MERCAPTOPURINE ANHYDROUS | Small molecule | — | Oral |
| Background | Prednisolone | Other / unclassified | — | Oral |
| Background | Teniposide | Small molecule | — | Intravenous |