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Evidence & citations 21 cited values
Every value below carries the sentence it was read from.
230 sources stand behind the page.
Field
Value
Cited text
Known as
MERCAPTOPURINE ANHYDROUS
ChEMBL registry synonym — accepted as the source's own labelCHEMBL1425 ↗
Known as
6-mercaptopurine
“The delayed-release test drugs are 6-mercaptopurine (at a dose of 40 mg daily) or calcitriol (at a dose of 5 mcg three times a week) versus Purinethol (6-MP at a dose of 1-2...” NCT00287170 ↗62
“continuous CT with 6 mercaptopurine (90 mg/m2/d, orally) and methotrexate (15 mg/m2/wk, oral-ly), according to a 2-by-2 factorial design stratified on the initial induction...” NCT00599937 ↗
“Oral 6-mercaptopurine with a starting dose of 25 mg/m2 and upward adjusted in steps of 25 mg/m2 (i.e. 50 or 75 mg/m2) if unacceptable bone-marrox toxicity is not encountered” NCT00816049 ↗
“Standard Chemotherapy (which includes cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate, 6-mercaptopurine, etoposide, and cytarabine” NCT03319901 ↗
“The longest treatment phase in both protocols is maintenance therapy, which is composed of 6-Mercaptopurine (6MP) and Methotrexate (MTX).” NCT02912676 ↗
“Maintenance therapy with dose-reduced POMP (6-mercaptopurine, vincristine, methotrexate, and prednisone) was given for 3 years.” PMID 37187201 ↗May 2023
“We aimed to compare the rates of POR in patients treated early with prophylactic 6-mercaptopurine (6-MP) or adalimumab.” PMID 38137669 ↗Dec 2023
“Patients randomized to IFX combination therapy will also receive 6-mercaptopurine 1-1.5 mg/kg.” NCT06059989 ↗
“6-Mercaptopurine by mouth daily NOTE: Only high risk patients will receive 6-Mercaptopurine” NCT02670707 ↗
“Initial dosage of 6-Mercaptopurine (6-MP) is stratified based on NUDT15 and TPMT genotypes:” NCT07462299 ↗
“Drug:6-mercaptopurine 60 mg/m2/d，po，d1-d28,during maintenance treatment for 2 years” NCT02042690 ↗
“a medicine called 6-mercaptopurine or "6MP" is taken by mouth every day at home” NCT06639958 ↗
“6-Mercaptopurine 60 milligrams per square meter per dose, orally, days 26-39” NCT02451774 ↗
“The IBD medications being observed are azathioprine and 6-mercaptopurine.” NCT04304950 ↗
“Allopurinol is added to standard oral 6-mercaptopurine and methotrexate” NCT03022747 ↗
ClinicalTrials.gov intervention name — accepted as the source's own labelNCT00136435 ↗
Known as
6-mercaptopurine monohydrate
ChEMBL registry synonym — accepted as the source's own labelCHEMBL1425 ↗
Known as
6MP
“Immunosuppressives, e.g. azathioprine (AZA) and 6-mercaptopurine (6-MP), are important in induction of remission and long term treatment of (ulcerative) colitis and Crohn's...” NCT00521950 ↗28
“Efficacy and myelosuppression of azathioprine/6-mercaptopurine (AZA/6-MP) are correlated with the metabolite 6-thioguanine, while the metabolite 6-methylmercaptopurine...” PMID 36730289 ↗Feb 2023
“The delayed-release test drugs are 6-mercaptopurine (at a dose of 40 mg daily) or calcitriol (at a dose of 5 mcg three times a week) versus Purinethol (6-MP at a dose of 1-2...” NCT00287170 ↗
“The study is designed to evaluate the clinical efficacy and safety of daily treatment for 12 weeks of oral administration of a delayed release, locally delivered 6MP...” NCT01094613 ↗
“Multi-agent chemotherapy including vincristine, prednisone, daunorubicin, cyclophosphamide, pegaspargase, cytarabine, 6-MP, MTX, and dexamethasone per protocol phases.” NCT07454226 ↗
“6MP will be administered orally starting at a dose of 6MP of 50mg/day with escalating doses every 1-2 weeks as tolerated, to a target dose of 1-1.5 mg/kg.” NCT01629628 ↗
“The longest treatment phase in both protocols is maintenance therapy, which is composed of 6-Mercaptopurine (6MP) and Methotrexate (MTX).” NCT02912676 ↗
“Patients should continue azathioprine or 6 MP or methotrexate at their previous doses for 6 months IMM therapy 26 weeks” NCT01802593 ↗
“6-mercaptopurine (6-MP) is a crucial drug in the maintenance phase of acute lymphoblastic leukemia treatment.” NCT06279767 ↗
“Initial dosage of 6-Mercaptopurine (6-MP) is stratified based on NUDT15 and TPMT genotypes:” NCT07462299 ↗
“Mercaptopurine (6MP) is essential to cure childhood acute lymphoblastic leukemia (ALL).” PMID 32519032 ↗Jun 2020
“a medicine called 6-mercaptopurine or "6MP" is taken by mouth every day at home” NCT06639958 ↗
“The study is designed to evaluate the clinical efficacy and safety of daily treatment for 12 weeks of oral administration of a delayed release, locally delivered 6MP...” NCT01094613 ↗
“plus thiopurine (initial dose of azathioprine 2·5 mg/kg or mercaptopurine 1·5 mg/kg, with dose adjustment based on thiopurine metabolite testing)” PMID 34890567 ↗Dec 2021
“Mercaptopurine (6MP) is essential to cure childhood acute lymphoblastic leukemia (ALL).” PMID 32519032 ↗Jun 2020
“Maintenance therapy with dose-reduced POMP (purinethol [6-mercaptopurine], oncovin [vincristine sulfate], methotrexate, and prednisone) was given for 3 years.” PMID 29352703 ↗Jan 20184
“Pharmacokinetics of 50 mg 6MP tablet (Puri-Nethol®) and 20 mg/ml 6MP liquid suspension (Xaluprine®) were compared” PMID 32519032 ↗Jun 2020