drugset / Trial / NCT02212574
Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma
Phase 0
Terminated
6 enrolled
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
The Matthew Larson Foundation for Pediatric Brain Tumors · collab
NaSingle-groupOpen-labelTreatment
Summary
Participants enrolling on this study will receive standard of care chemotherapy for Wnt positive medulloblastoma without the radiation therapy or the weekly chemotherapy that is given during radiation therapy.
Timeline
- Start
- 2017-04-04
- Primary completion
- 2018-11-09
- Completion
- 2018-11-09
Outcome
Outcome not reported
Stopped: “Participant relapses led to abrupt stop of study.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | — | Intravenous |
| Subject | Cyclophosphamide | Other / unclassified | — | Intravenous |
| Subject | Lomustine | Small molecule | — | Oral |
| Subject | Vincristine | Small molecule | — | Intravenous |
| Background | 2-MERCAPTOETHANESULFONIC ACID | Small molecule | — | — |