drugset / Trial / NCT05495893
MMF Versus CYC in the Induction Therapy of Pediatric Active Proliferative LN
Phase 4
Unknown
224 enrolled
Second Xiangya Hospital of Central South University
Beijing Children's Hospital · collabChildren's Hospital of Chongqing Medical University · collabJiangxi Province Children's Hospital · collabPeking Union Medical College Hospital · collabShenzhen Children's Hospital · collabThe Affiliated Hospital of Qingdao University · collabThe Children's Hospital of Zhejiang University School of Medicine · collabThe First Affiliated Hospital of Zhengzhou University · collabThe Second Hospital of Hebei Medical University · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
A prospective, randomized, multicenter, open-label, parallel-arm Study to compare effectiveness of mycophenolate mofetil versus cyclophosphamide in the Induction Therapy of pediatric patients with Active Proliferative Lupus Nephritis in Chinese population
Timeline
- Start
- 2022-07-25
- Primary completion
- 2025-05-31
- Completion
- 2025-05-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | 750 mg/m2 | — |
| Subject | Mycophenolate Mofetil | Small molecule | 30 mg/kg | — |
| Subject | Mycophenolate Mofetil | Small molecule | 40 mg/kg | — |