drugset / Trial / NCT07652879

KCD (Carfilzomib/Cyclophosphamide/Dexamethasone) Regimen for the Treatment of Newly Diagnosed POEMS Syndrome

NCT07652879

Phase 2 Recruiting 20 enrolled Shanghai Changzheng Hospital
NaSingle-groupOpen-labelTreatment

Summary

This study is a single-center, prospective, open-label clinical study to evaluate the efficacy and safety of KCD(Carfilzomib/Cyclophosphamide/Dexamethasone) regimen in subjects with newly diagnosed POEMS Syndrome.

Timeline

Start
2026-06-15
Primary completion
2028-01
Completion
2028-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Carfilzomib Other / unclassified 27 mg/m2 Intravenous
Subject Cyclophosphamide Other / unclassified 200 mg/m2 Intravenous
Subject Dexamethasone Small molecule 10 mg
Subject Dexamethasone Small molecule 20 mg

Indications