drugset / Trial / NCT07590752
"Dexa vs Dexmedetomidine With Bupivacaine in TAP Block for Laparotomy Analgesia
RandomizedParallel-groupDouble-blindTreatment
Summary
Transversus abdominis plane block is a regional anesthetic technique which blocks the abdominal neural afferents by introducing local anesthetic into the neuro-fascial plane between the internal oblique and the transversus abdominis muscle and gives analgesia from the skin to parietal peritoneum. There are studies showing evidence of improved post operative analgesia with addition of adjuvants such as dexmedetomidine or dexamethasone in comparison with plane local anesthesia in terms of time to rescue analgesia and the overall quantity of analgesic used post operatively.
Timeline
- Start
- 2024-03-03
- Primary completion
- 2026-06-03
- Completion
- 2026-07-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | 8 mg | Other |
| Subject | Dexmedetomidine | Other / unclassified | 1 ug/kg | Other |
| Background | Bupivacaine | Other / unclassified | 0.25 % | Other |
| Background | Bupivacaine | Other / unclassified | 18 ml | Other |