Desmopressin and Dexamethasone Adjunctive Treatment for Leptospirosis

Summary

Background: Pulmonary involvement in leptospirosis has been reported to be on the increase and is emerging as the main cause of death due to leptospirosis in many countries, including Thailand. Methods: A prospective randomized controlled trial of desmopressin or high dose dexamethasone as adjunctive therapy in patients with suspected pulmonary hemorrhage associated with leptospirosis was conducted between July 2003 and October 2006 at 5 hospitals in Thailand.

Timeline

Start

2003-07

Primary completion

2006-10

Completion

2006-10

Drugs

Indications