Safety and Efficacy of Early Administration of Dexamethasone in High-risk Sepsis

Phase 1/2 Completed 102 enrolled CHA University

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to investigate the safety and efficacy of early administration of two different doses of dexamethasone in high risk septic patients.

Timeline

Start: 2022-03-01
Primary completion: 2026-02-28
Completion: 2026-02-28

Publications

Choi K, Park JE, Kim A, Hwang S, Bae J, Shin TG, Kim K. The DEXA-SEPSIS study protocol: a phase II randomized double-blinded controlled trial of the effect of early dexamethasone in high-risk sepsis patients. Clin Exp Emerg Med. 2022 Sep;9(3):246-252. doi: 10.15441/ceem.22.276. Epub 2022 Sep 20.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dexamethasone	Small molecule	0.1 mg/kg	Intravenous
Subject	Dexamethasone	Small molecule	0.2 mg/kg	Intravenous

Safety and Efficacy of Early Administration of Dexamethasone in High-risk Sepsis

Summary

Timeline

Publications

Drugs

Indications