drugset / Trial / NCT02204241

Study of Carfilzomib, Cyclophosphamide and Dexamethasone in Newly Diagnosed Multiple Myeloma Patients

NCT02204241

NaSingle-groupOpen-labelTreatment

Summary

This protocol is a phase I/II multicenter study designed to assess the safety and the efficacy of the proposed combinations as up-front treatment in elderly Multiple Myeloma (MM) patients.

Timeline

Start
2014-06
Primary completion
2015-06
Completion
2023-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Carfilzomib Other / unclassified 36 mg/m2 Intravenous
Subject Carfilzomib Other / unclassified 45 mg/m2 Intravenous
Subject Carfilzomib Other / unclassified 56 mg/m2 Intravenous
Subject Carfilzomib Other / unclassified 70 mg/m2 Intravenous
Subject Cyclophosphamide Other / unclassified 300 mg/m2 Oral
Subject Dexamethasone Small molecule 20 mg Oral
Subject Dexamethasone Small molecule 40 mg Oral

Indications