drugset / Trial / NCT00953303
The Effects of Glucocorticoids on Mortality and Renal Function in Patients With Acute Decompensated Heart Failure
RandomizedParallel-groupOpen-labelTreatment
Summary
Evidence showed that glucocorticoids could induce potent diuretic actions and improve renal functions in patients with decompensated congestive heart failure. Thus we design this study to determine the efficacy of glucocorticoids on cardiovascular mortality in the 30 days following randomization.
Timeline
- Start
- 2009-01
- Primary completion
- 2011-09
- Completion
- 2012-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | 20 mg | — |
| Subject | Prednisone | Other / unclassified | 1 mg/kg | — |
| Comparator | Dobutamine | Small molecule | — | — |
| Comparator | Dopamine | Small molecule | — | — |
| Comparator | Furosemide | Other / unclassified | — | — |
| Comparator | Nitroglycerin | Unknown | — | — |
| Comparator | Torsemide | Other / unclassified | — | — |